WWTR1-IT1

Summary

WWTR1-IT1 (WWTR1 intronic transcript 1, HGNC:41469) is a long non-coding RNA gene on chromosome 3q25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41469
Approved symbol	WWTR1-IT1
Name	WWTR1 intronic transcript 1
Location	3q25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000241985
Ensembl biotype	lncRNA
Entrez	106478977
RNAcentral	URS00025E354C — lncRNA, 2312 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000463167

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000463167 — 2 exons

Exon	Start	End
ENSE00001874523	149648997	149649102
ENSE00001936941	149649840	149650184

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 80.23.

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.23	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.26	silver quality
colonic epithelium	UBERON:0000397	77.89	gold quality
sural nerve	UBERON:0015488	75.30	gold quality
ventricular zone	UBERON:0003053	67.69	gold quality
skeletal muscle tissue	UBERON:0001134	67.10	gold quality
cortical plate	UBERON:0005343	67.05	gold quality
adrenal tissue	UBERON:0018303	66.83	gold quality
tonsil	UBERON:0002372	65.75	gold quality
urinary bladder	UBERON:0001255	63.62	gold quality
muscle tissue	UBERON:0002385	63.47	gold quality
calcaneal tendon	UBERON:0003701	62.38	gold quality
uterine cervix	UBERON:0000002	61.56	gold quality
gall bladder	UBERON:0002110	61.45	gold quality
mucosa of stomach	UBERON:0001199	60.56	gold quality
corpus callosum	UBERON:0002336	60.33	gold quality
lung	UBERON:0002048	60.03	gold quality
descending thoracic aorta	UBERON:0002345	59.81	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.80	gold quality
endometrium	UBERON:0001295	59.73	gold quality
superior frontal gyrus	UBERON:0002661	59.63	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	59.55	gold quality
ovary	UBERON:0000992	59.54	gold quality
bone marrow	UBERON:0002371	59.37	gold quality
ascending aorta	UBERON:0001496	59.08	gold quality
ectocervix	UBERON:0012249	58.95	gold quality
primary visual cortex	UBERON:0002436	58.93	gold quality
thoracic aorta	UBERON:0001515	58.91	gold quality
tibial artery	UBERON:0007610	58.85	gold quality
left ovary	UBERON:0002119	58.83	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.87

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.