XIAP-AS1

Summary

XIAP-AS1 (XIAP antisense RNA 1, HGNC:40078) is a long non-coding RNA gene on chromosome Xq25.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40078
Approved symbol	XIAP-AS1
Name	XIAP antisense RNA 1
Location	Xq25
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237331
Ensembl biotype	lncRNA
Entrez	106480735
RNAcentral	URS000021CBC1 — lncRNA, 482 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000458331

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000458331 — 2 exons

Exon	Start	End
ENSE00001607069	123872626	123872983
ENSE00001680275	123873809	123873932

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 80.70.

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.70	silver quality
colonic epithelium	UBERON:0000397	76.95	gold quality
skeletal muscle tissue	UBERON:0001134	72.12	gold quality
urinary bladder	UBERON:0001255	67.71	gold quality
muscle tissue	UBERON:0002385	67.40	gold quality
bone marrow cell	CL:0002092	65.98	silver quality
tonsil	UBERON:0002372	65.91	silver quality
sural nerve	UBERON:0015488	65.79	gold quality
adrenal tissue	UBERON:0018303	63.17	gold quality
liver	UBERON:0002107	61.48	silver quality
blood	UBERON:0000178	58.07	gold quality
calcaneal tendon	UBERON:0003701	57.02	gold quality
stromal cell of endometrium	CL:0002255	56.69	gold quality
leukocyte	CL:0000738	55.99	gold quality
uterine cervix	UBERON:0000002	55.14	silver quality
monocyte	CL:0000576	54.43	gold quality
prefrontal cortex	UBERON:0000451	54.14	gold quality
islet of Langerhans	UBERON:0000006	53.09	gold quality
kidney	UBERON:0002113	52.66	gold quality
primary visual cortex	UBERON:0002436	52.37	gold quality
muscle of leg	UBERON:0001383	51.30	gold quality
pancreas	UBERON:0001264	51.20	gold quality
adrenal gland	UBERON:0002369	51.12	gold quality
gastrocnemius	UBERON:0001388	50.55	gold quality
lung	UBERON:0002048	50.27	gold quality
superior frontal gyrus	UBERON:0002661	50.11	gold quality
heart left ventricle	UBERON:0002084	49.35	gold quality
placenta	UBERON:0001987	49.33	gold quality
left uterine tube	UBERON:0001303	49.27	gold quality
endometrium	UBERON:0001295	49.10	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.24

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Results show that XIAP-AS enhances XIAP transcription via interacting with Sp1 and that XIAP-AS may be a potential therapeutic target for gastric cancer. (PMID:28792527)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.