XPC-AS1

Summary

XPC-AS1 (XPC antisense RNA 1, HGNC:55014) is a long non-coding RNA gene on chromosome 3p25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55014
Approved symbol	XPC-AS1
Name	XPC antisense RNA 1
Location	3p25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228242
Ensembl biotype	lncRNA
Entrez	107986063
RNAcentral	URS0000812092 — lncRNA, 1514 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000420253, ENST00000428681, ENST00000626655, ENST00000627116, ENST00000627385, ENST00000627997, ENST00000628412, ENST00000628446, ENST00000628760, ENST00000628785, ENST00000628791, ENST00000628978, ENST00000629301, ENST00000629708, ENST00000629796, ENST00000630173, ENST00000630772

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000420253 — 3 exons

Exon	Start	End
ENSE00001705822	14145322	14145456
ENSE00001765475	14144637	14145095
ENSE00003773960	14147951	14148423

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 96.80.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.5768 / max 51.1582, expressed in 147 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
35442	0.4340	121
35441	0.1428	50

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	96.80	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	92.59	gold quality
blood	UBERON:0000178	90.59	gold quality
fallopian tube	UBERON:0003889	89.70	gold quality
pituitary gland	UBERON:0000007	88.79	gold quality
left lobe of thyroid gland	UBERON:0001120	88.74	gold quality
thyroid gland	UBERON:0002046	88.60	gold quality
right lobe of thyroid gland	UBERON:0001119	88.55	gold quality
endocervix	UBERON:0000458	88.45	gold quality
skin of leg	UBERON:0001511	88.34	gold quality
zone of skin	UBERON:0000014	88.13	gold quality
adenohypophysis	UBERON:0002196	88.10	gold quality
skin of abdomen	UBERON:0001416	87.94	gold quality
right ovary	UBERON:0002118	87.64	gold quality
left ovary	UBERON:0002119	87.54	gold quality
mucosa of stomach	UBERON:0001199	87.41	gold quality
body of uterus	UBERON:0009853	87.34	gold quality
body of pancreas	UBERON:0001150	87.31	gold quality
tibial nerve	UBERON:0001323	87.23	gold quality
metanephros cortex	UBERON:0010533	86.93	gold quality
spleen	UBERON:0002106	86.82	gold quality
right lung	UBERON:0002167	86.79	gold quality
left uterine tube	UBERON:0001303	86.78	gold quality
small intestine Peyer’s patch	UBERON:0003454	86.69	gold quality
uterine cervix	UBERON:0000002	86.68	gold quality
ovary	UBERON:0000992	86.46	gold quality
right lobe of liver	UBERON:0001114	86.05	gold quality
muscle layer of sigmoid colon	UBERON:0035805	86.02	gold quality
sural nerve	UBERON:0015488	85.91	gold quality
descending thoracic aorta	UBERON:0002345	85.89	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.66

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.