YTHDF3-DT

Summary

YTHDF3-DT (YTHDF3 divergent transcript, HGNC:48728) is a long non-coding RNA gene on chromosome 8q12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48728
Approved symbol	YTHDF3-DT
Name	YTHDF3 divergent transcript
Location	8q12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000270673
Ensembl biotype	lncRNA
Entrez	101410533
RNAcentral	URS000075BFB1 — lncRNA, 736 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000603538

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000603538 — 1 exons

Exon	Start	End
ENSE00004205270	63167485	63169063

Expression profiles

Bgee: expression breadth ubiquitous, 161 present calls, max score 89.86.

FANTOM5 (CAGE): breadth broad, TPM avg 0.9650 / max 25.0981, expressed in 540 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
93331	0.9650	540

Top tissues by expression

247 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.86	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	87.47	gold quality
pancreatic ductal cell	CL:0002079	84.88	silver quality
tendon of biceps brachii	UBERON:0008188	74.87	gold quality
right adrenal gland	UBERON:0001233	73.48	gold quality
right adrenal gland cortex	UBERON:0035827	72.99	gold quality
adenohypophysis	UBERON:0002196	72.08	gold quality
left adrenal gland	UBERON:0001234	71.87	gold quality
left adrenal gland cortex	UBERON:0035825	71.84	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	71.77	gold quality
right lobe of liver	UBERON:0001114	70.96	gold quality
granulocyte	CL:0000094	70.89	gold quality
left testis	UBERON:0004533	70.76	gold quality
mucosa of transverse colon	UBERON:0004991	70.70	gold quality
right testis	UBERON:0004534	70.54	gold quality
adrenal cortex	UBERON:0001235	69.87	gold quality
bone marrow cell	CL:0002092	69.58	gold quality
pituitary gland	UBERON:0000007	69.35	gold quality
testis	UBERON:0000473	68.75	gold quality
adrenal gland	UBERON:0002369	68.59	gold quality
gastrocnemius	UBERON:0001388	68.48	gold quality
muscle of leg	UBERON:0001383	68.11	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.88	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	67.36	gold quality
mucosa of stomach	UBERON:0001199	66.46	gold quality
leukocyte	CL:0000738	65.92	gold quality
monocyte	CL:0000576	65.70	gold quality
skin of leg	UBERON:0001511	65.46	gold quality
metanephros cortex	UBERON:0010533	65.37	gold quality
tibialis anterior	UBERON:0001385	65.29	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.87

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.