YWHAH-AS1

Summary

YWHAH-AS1 (YWHAH antisense RNA 1, HGNC:23051) is a long non-coding RNA gene on chromosome 22q12.3.

Predicted to be located in membrane.

Source: NCBI Gene 25775 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:23051
Approved symbol	YWHAH-AS1
Name	YWHAH antisense RNA 1
Location	22q12.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	HSN44A4A
Ensembl gene	ENSG00000128254
Ensembl biotype	lncRNA
Entrez	25775
RNAcentral	URS0002123254 — lncRNA, 1186 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000484682, ENST00000486651, ENST00000623735, ENST00000641789, ENST00000654264, ENST00000667186, ENST00000670472, ENST00000676309, ENST00000819534, ENST00000819535, ENST00000819536

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000484682 — 5 exons

Exon	Start	End
ENSE00001490923	31945233	31945346
ENSE00001900611	31937989	31938115
ENSE00003874445	31933336	31934449
ENSE00003899359	31928163	31928268
ENSE00003899879	31925519	31926551

Expression profiles

Bgee: expression breadth ubiquitous, 162 present calls, max score 74.55.

Top tissues by expression

280 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
tibialis anterior	UBERON:0001385	74.55	silver quality
cortical plate	UBERON:0005343	73.03	gold quality
Brodmann (1909) area 10	UBERON:0013541	72.27	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	72.05	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	71.57	gold quality
prefrontal cortex	UBERON:0000451	68.39	gold quality
ganglionic eminence	UBERON:0004023	66.99	gold quality
ileal mucosa	UBERON:0000331	66.32	silver quality
bone marrow cell	CL:0002092	66.23	gold quality
cingulate cortex	UBERON:0003027	64.29	gold quality
anterior cingulate cortex	UBERON:0009835	64.13	gold quality
right frontal lobe	UBERON:0002810	63.75	gold quality
colonic epithelium	UBERON:0000397	63.61	silver quality
ventricular zone	UBERON:0003053	63.48	gold quality
endometrium epithelium	UBERON:0004811	63.38	gold quality
Brodmann (1909) area 9	UBERON:0013540	62.67	gold quality
neocortex	UBERON:0001950	62.28	gold quality
nucleus accumbens	UBERON:0001882	62.24	gold quality
frontal cortex	UBERON:0001870	62.14	gold quality
frontal pole	UBERON:0002795	61.89	gold quality
paraflocculus	UBERON:0005351	61.10	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	60.89	gold quality
pancreatic ductal cell	CL:0002079	60.88	silver quality
stromal cell of endometrium	CL:0002255	60.63	gold quality
skin of hip	UBERON:0001554	60.62	silver quality
granulocyte	CL:0000094	59.97	gold quality
embryo	UBERON:0000922	59.51	gold quality
deltoid	UBERON:0001476	59.49	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.40	gold quality
cerebral cortex	UBERON:0000956	59.14	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.22

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.