ZBED5-AS1

Summary

ZBED5-AS1 (ZBED5 antisense RNA 1, HGNC:48646) is a long non-coding RNA gene on chromosome 11p15.4.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48646
Approved symbol	ZBED5-AS1
Name	ZBED5 antisense RNA 1
Location	11p15.4
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000247271
Ensembl biotype	lncRNA
Entrez	729013
RNAcentral	URS000075D0BB — lncRNA, 1113 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 19 — 19 lncRNA

ENST00000501079, ENST00000529014, ENST00000530344, ENST00000654337, ENST00000658394, ENST00000664153, ENST00000664276, ENST00000666098, ENST00000669704, ENST00000702629, ENST00000702973, ENST00000837193, ENST00000837194, ENST00000837195, ENST00000837196, ENST00000837197, ENST00000837198, ENST00000837199, ENST00000837200

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000501079 — 3 exons

Exon	Start	End
ENSE00001978070	10865261	10865327
ENSE00004257430	10878381	10879278
ENSE00004257443	10858213	10858351

Expression profiles

Bgee: expression breadth ubiquitous, 239 present calls, max score 97.24.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 14.1894 / max 147.9559, expressed in 1803 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
113075	13.6035	1801
113076	0.3391	154
206188	0.2468	87

Top tissues by expression

249 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
oviduct epithelium	UBERON:0004804	97.24	gold quality
corpus epididymis	UBERON:0004359	97.05	gold quality
bronchial epithelial cell	CL:0002328	94.22	gold quality
bronchus	UBERON:0002185	93.47	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	93.41	gold quality
kidney epithelium	UBERON:0004819	93.30	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	93.07	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	92.56	gold quality
sperm	CL:0000019	92.53	gold quality
ileal mucosa	UBERON:0000331	92.25	gold quality
caput epididymis	UBERON:0004358	92.24	gold quality
left testis	UBERON:0004533	91.64	gold quality
testis	UBERON:0000473	91.62	gold quality
right testis	UBERON:0004534	91.57	gold quality
parotid gland	UBERON:0001831	91.47	gold quality
right uterine tube	UBERON:0001302	90.59	gold quality
islet of Langerhans	UBERON:0000006	90.28	gold quality
renal medulla	UBERON:0000362	90.11	gold quality
upper arm skin	UBERON:0004263	90.05	gold quality
cauda epididymis	UBERON:0004360	89.93	gold quality
pancreatic ductal cell	CL:0002079	89.59	silver quality
adult organism	UBERON:0007023	89.55	gold quality
mucosa of paranasal sinus	UBERON:0005030	88.42	gold quality
pituitary gland	UBERON:0000007	88.28	gold quality
fallopian tube	UBERON:0003889	88.13	gold quality
adenohypophysis	UBERON:0002196	87.99	gold quality
right adrenal gland cortex	UBERON:0035827	87.37	gold quality
left ventricle myocardium	UBERON:0006566	87.33	gold quality
right adrenal gland	UBERON:0001233	87.22	gold quality
left adrenal gland cortex	UBERON:0035825	87.09	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	7.23

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long Noncoding RNA ZBED5-AS1 Facilitates Tumor Progression and Metastasis in Lung Adenocarcinoma via ZNF146/ATR/Chk1 Axis. (PMID:37762228)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.