ZBTB11-AS1

Summary

ZBTB11-AS1 (ZBTB11 antisense RNA 1, HGNC:48573) is a long non-coding RNA gene on chromosome 3q12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48573
Approved symbol	ZBTB11-AS1
Name	ZBTB11 antisense RNA 1
Location	3q12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256628
Ensembl biotype	lncRNA
Entrez	100009676
RNAcentral	URS0000759C0C — lncRNA, 2788 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000609682, ENST00000851071

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000609682 — 1 exons

Exon	Start	End
ENSE00004158771	101676421	101679217

Expression profiles

Bgee: expression breadth ubiquitous, 163 present calls, max score 72.59.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 5.8429 / max 75.2944, expressed in 1725 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
37647	5.8429	1725

Top tissues by expression

243 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	72.59	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	70.94	gold quality
stromal cell of endometrium	CL:0002255	70.90	gold quality
granulocyte	CL:0000094	70.87	gold quality
leukocyte	CL:0000738	70.57	gold quality
monocyte	CL:0000576	70.55	gold quality
bone marrow cell	CL:0002092	68.56	silver quality
descending thoracic aorta	UBERON:0002345	68.35	gold quality
thoracic aorta	UBERON:0001515	67.46	gold quality
left coronary artery	UBERON:0001626	67.46	gold quality
ascending aorta	UBERON:0001496	67.27	gold quality
aorta	UBERON:0000947	66.86	gold quality
gastrocnemius	UBERON:0001388	66.85	gold quality
popliteal artery	UBERON:0002250	66.69	gold quality
tibial artery	UBERON:0007610	66.67	gold quality
right atrium auricular region	UBERON:0006631	66.60	gold quality
left adrenal gland	UBERON:0001234	66.51	gold quality
left lobe of thyroid gland	UBERON:0001120	66.33	gold quality
muscle of leg	UBERON:0001383	66.30	gold quality
right lobe of thyroid gland	UBERON:0001119	66.27	gold quality
left adrenal gland cortex	UBERON:0035825	66.23	gold quality
cardiac atrium	UBERON:0002081	65.93	gold quality
right coronary artery	UBERON:0001625	65.89	gold quality
coronary artery	UBERON:0001621	65.86	gold quality
colonic epithelium	UBERON:0000397	65.76	silver quality
right adrenal gland	UBERON:0001233	65.69	gold quality
islet of Langerhans	UBERON:0000006	65.65	gold quality
apex of heart	UBERON:0002098	65.62	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	65.39	gold quality
esophagus mucosa	UBERON:0002469	65.38	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.07

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Spatial transcriptomics unveils ZBTB11 as a regulator of cardiomyocyte degeneration in arrhythmogenic cardiomyopathy. (PMID:35576477)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.