ZBTB44-DT

Summary

ZBTB44-DT (ZBTB44 divergent transcript, HGNC:54265) is a long non-coding RNA gene on chromosome 11q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54265
Approved symbol	ZBTB44-DT
Name	ZBTB44 divergent transcript
Location	11q24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000175773
Ensembl biotype	lncRNA
Entrez	646383
RNAcentral	URS0000BC44D8 — lncRNA, 992 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 29 — 29 lncRNA

ENST00000532116, ENST00000602310, ENST00000602376, ENST00000616197, ENST00000649867, ENST00000701296, ENST00000701337, ENST00000777858, ENST00000777859, ENST00000777860, ENST00000777861, ENST00000777862, ENST00000777863, ENST00000777864, ENST00000777865, ENST00000777866, ENST00000777867, ENST00000777868, ENST00000777869, ENST00000777870, ENST00000777871, ENST00000777872, ENST00000777873, ENST00000777874, ENST00000777875, ENST00000777876, ENST00000777877, ENST00000777878, ENST00000777879

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000532116 — 6 exons

Exon	Start	End
ENSE00002189987	130393719	130393793
ENSE00002237432	130323914	130324061
ENSE00003069605	130315028	130315115
ENSE00003105678	130333864	130333970
ENSE00003309920	130393495	130393596
ENSE00003441183	130368894	130369042

Expression profiles

Bgee: expression breadth ubiquitous, 157 present calls, max score 83.13.

FANTOM5 (CAGE): breadth broad, TPM avg 0.7442 / max 54.2742, expressed in 403 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
117633	0.3769	186
117634	0.3309	152
117635	0.0365	14

Top tissues by expression

243 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	83.13	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.06	gold quality
right testis	UBERON:0004534	82.43	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.87	gold quality
testis	UBERON:0000473	79.47	gold quality
bone marrow cell	CL:0002092	74.65	silver quality
right uterine tube	UBERON:0001302	70.57	gold quality
granulocyte	CL:0000094	69.47	gold quality
colonic epithelium	UBERON:0000397	68.99	silver quality
mucosa of transverse colon	UBERON:0004991	67.72	gold quality
metanephros cortex	UBERON:0010533	66.97	gold quality
body of pancreas	UBERON:0001150	66.52	gold quality
right lobe of liver	UBERON:0001114	66.31	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	66.18	gold quality
right adrenal gland cortex	UBERON:0035827	65.70	gold quality
right adrenal gland	UBERON:0001233	65.45	gold quality
left lobe of thyroid gland	UBERON:0001120	65.30	gold quality
pancreas	UBERON:0001264	64.58	gold quality
right lobe of thyroid gland	UBERON:0001119	64.40	gold quality
thyroid gland	UBERON:0002046	64.32	gold quality
adult mammalian kidney	UBERON:0000082	64.17	gold quality
left adrenal gland	UBERON:0001234	62.99	gold quality
islet of Langerhans	UBERON:0000006	62.88	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.29	gold quality
adenohypophysis	UBERON:0002196	61.91	gold quality
left adrenal gland cortex	UBERON:0035825	61.75	gold quality
cortex of kidney	UBERON:0001225	61.73	gold quality
sural nerve	UBERON:0015488	61.72	silver quality
body of stomach	UBERON:0001161	61.60	gold quality
pituitary gland	UBERON:0000007	61.50	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.15

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.