ZBTB46-AS1

Summary

ZBTB46-AS1 (ZBTB46 antisense RNA 1, HGNC:40753) is a long non-coding RNA gene on chromosome 20q13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40753
Approved symbol	ZBTB46-AS1
Name	ZBTB46 antisense RNA 1
Location	20q13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231208
Ensembl biotype	lncRNA
Entrez	101928604
RNAcentral	URS000075D537 — lncRNA, 1096 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000435912, ENST00000775272, ENST00000775273

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000435912 — 3 exons

Exon	Start	End
ENSE00001741838	63816353	63816521
ENSE00004141910	63808024	63808155
ENSE00004141911	63814887	63815170

Expression profiles

Bgee: expression breadth ubiquitous, 111 present calls, max score 97.69.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0332 / max 10.0675, expressed in 16 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
185883	0.0332	16

Top tissues by expression

111 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	97.69	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.89	silver quality
colonic epithelium	UBERON:0000397	70.18	silver quality
hindlimb stylopod muscle	UBERON:0004252	64.93	gold quality
skeletal muscle tissue	UBERON:0001134	64.78	gold quality
right testis	UBERON:0004534	61.17	gold quality
testis	UBERON:0000473	60.63	gold quality
left testis	UBERON:0004533	60.44	gold quality
muscle tissue	UBERON:0002385	58.87	gold quality
liver	UBERON:0002107	57.50	gold quality
lymph node	UBERON:0000029	56.78	gold quality
placenta	UBERON:0001987	56.73	gold quality
spleen	UBERON:0002106	53.85	gold quality
monocyte	CL:0000576	53.45	gold quality
cerebellum	UBERON:0002037	53.45	gold quality
cerebellar cortex	UBERON:0002129	53.33	gold quality
islet of Langerhans	UBERON:0000006	53.21	gold quality
cerebellar hemisphere	UBERON:0002245	53.20	gold quality
blood	UBERON:0000178	52.94	gold quality
vermiform appendix	UBERON:0001154	52.63	gold quality
calcaneal tendon	UBERON:0003701	52.61	silver quality
urinary bladder	UBERON:0001255	52.23	gold quality
right hemisphere of cerebellum	UBERON:0014890	52.11	gold quality
kidney	UBERON:0002113	52.09	gold quality
muscle of leg	UBERON:0001383	51.32	gold quality
primary visual cortex	UBERON:0002436	50.95	gold quality
adrenal tissue	UBERON:0018303	50.71	gold quality
gastrocnemius	UBERON:0001388	50.62	gold quality
heart left ventricle	UBERON:0002084	49.76	gold quality
adult mammalian kidney	UBERON:0000082	49.28	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.09

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.