ZC3H18-DT

Summary

ZC3H18-DT (ZC3H18 divergent transcript, HGNC:33799) is a long non-coding RNA gene on chromosome 16q24.2.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33799
Approved symbol	ZC3H18-DT
Name	ZC3H18 divergent transcript
Location	16q24.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ45530
Entrez	400555
RNAcentral	URS0000BC44B2 — lncRNA, 1224 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000055126 (16:88563844 C>T), RS1000183139 (16:88563550 A>C,G), RS1000650216 (16:88561416 C>G), RS1000916122 (16:88561064 G>A), RS1001133147 (16:88560789 A>G), RS1001830285 (16:88561690 G>A), RS1001847396 (16:88560523 T>A), RS1002125883 (16:88561820 G>A,T), RS1003395811 (16:88562964 A>T), RS1003862469 (16:88562355 T>C), RS1003898282 (16:88562669 G>A), RS1004620206 (16:88563035 T>C), RS1005366877 (16:88561059 C>T), RS1006574255 (16:88561263 G>C), RS1007423451 (16:88560171 C>G,T)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

5 total (human), top 5 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
titanium dioxide	increases expression	1
Air Pollutants	decreases expression, increases abundance	1
Gold Compounds	increases expression	1
Particulate Matter	decreases expression, increases abundance	1
Magnetite Nanoparticles	increases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.