ZFHX3-AS1

Summary

ZFHX3-AS1 (ZFHX3 antisense RNA 1, HGNC:56033) is a long non-coding RNA gene on chromosome 16q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56033
Approved symbol	ZFHX3-AS1
Name	ZFHX3 antisense RNA 1
Location	16q22.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC004943.2
Ensembl gene	ENSG00000259768
Ensembl biotype	lncRNA
Entrez	101927978
RNAcentral	URS00021ED9E2 — lncRNA, 1272 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 97 — 97 lncRNA

ENST00000558618, ENST00000563328, ENST00000620814, ENST00000624370, ENST00000653037, ENST00000668995, ENST00000686426, ENST00000687589, ENST00000689200, ENST00000692742, ENST00000692937, ENST00000700870, ENST00000701465, ENST00000701474, ENST00000702197, ENST00000766455, ENST00000766456, ENST00000766457, ENST00000766458, ENST00000766459, ENST00000766460, ENST00000766461, ENST00000766462, ENST00000766463, ENST00000766464, ENST00000766465, ENST00000766466, ENST00000766467, ENST00000766468, ENST00000766469, ENST00000766470, ENST00000766471, ENST00000766472, ENST00000766473, ENST00000766474, ENST00000766475, ENST00000766476, ENST00000766477, ENST00000766478, ENST00000766479, ENST00000766480, ENST00000766481, ENST00000766482, ENST00000766483, ENST00000766484, ENST00000766485, ENST00000766486, ENST00000766487, ENST00000766488, ENST00000766489, ENST00000766490, ENST00000766491, ENST00000766492, ENST00000766493, ENST00000766494, ENST00000766495, ENST00000766496, ENST00000766497, ENST00000766498, ENST00000766499, ENST00000766500, ENST00000766501, ENST00000766502, ENST00000766503, ENST00000766504, ENST00000766505, ENST00000766506, ENST00000766507, ENST00000766508, ENST00000766509, ENST00000766510, ENST00000766511, ENST00000766512, ENST00000766513, ENST00000766514, ENST00000766515, ENST00000766516, ENST00000766517, ENST00000766518, ENST00000766519, ENST00000766520, ENST00000766521, ENST00000766522, ENST00000766523, ENST00000766524, ENST00000766525, ENST00000766526, ENST00000766527, ENST00000766528, ENST00000766529, ENST00000766530, ENST00000766531, ENST00000766532, ENST00000766533, ENST00000766534, ENST00000766535, ENST00000766948

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000558618 — 2 exons

Exon	Start	End
ENSE00002537926	72806983	72807192
ENSE00002558029	72809347	72809639

Expression profiles

Bgee: expression breadth ubiquitous, 165 present calls, max score 99.45.

Top tissues by expression

247 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.45	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	88.39	gold quality
hindlimb stylopod muscle	UBERON:0004252	79.83	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.42	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.24	gold quality
ventricular zone	UBERON:0003053	75.66	gold quality
calcaneal tendon	UBERON:0003701	74.22	gold quality
ganglionic eminence	UBERON:0004023	72.07	gold quality
secondary oocyte	CL:0000655	70.95	gold quality
stromal cell of endometrium	CL:0002255	70.76	gold quality
bone marrow cell	CL:0002092	69.14	silver quality
islet of Langerhans	UBERON:0000006	68.35	gold quality
colonic epithelium	UBERON:0000397	68.01	silver quality
cortical plate	UBERON:0005343	67.87	gold quality
smooth muscle tissue	UBERON:0001135	67.44	gold quality
adrenal tissue	UBERON:0018303	67.42	gold quality
left ovary	UBERON:0002119	67.24	gold quality
left testis	UBERON:0004533	66.72	gold quality
right testis	UBERON:0004534	66.72	gold quality
testis	UBERON:0000473	66.68	gold quality
right uterine tube	UBERON:0001302	65.89	gold quality
monocyte	CL:0000576	65.50	gold quality
ovary	UBERON:0000992	65.43	gold quality
leukocyte	CL:0000738	65.37	gold quality
right ovary	UBERON:0002118	65.34	gold quality
right adrenal gland	UBERON:0001233	64.87	gold quality
bronchial epithelial cell	CL:0002328	64.83	silver quality
rectum	UBERON:0001052	64.82	gold quality
adult mammalian kidney	UBERON:0000082	64.77	gold quality
right adrenal gland cortex	UBERON:0035827	64.59	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.83

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.