ZFHX3-AS2

Summary

ZFHX3-AS2 (ZFHX3 antisense RNA 2, HGNC:58537) is a long non-coding RNA gene on chromosome 16q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58537
Approved symbol	ZFHX3-AS2
Name	ZFHX3 antisense RNA 2
Location	16q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260848
Ensembl biotype	lncRNA
Entrez	142592810

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000567227, ENST00000658533, ENST00000666029, ENST00000813329, ENST00000813330, ENST00000813331, ENST00000813332, ENST00000813333, ENST00000813334, ENST00000813335, ENST00000813336, ENST00000813337, ENST00000813338, ENST00000813339, ENST00000813340, ENST00000813341, ENST00000813342

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000567227 — 4 exons

Exon	Start	End
ENSE00002586260	73554272	73554317
ENSE00002594063	73558268	73558522
ENSE00002601208	73543941	73544008
ENSE00002619212	73554649	73554811

Expression profiles

Bgee: expression breadth broad, 60 present calls, max score 88.39.

Top tissues by expression

60 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.39	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	63.45	gold quality
nucleus accumbens	UBERON:0001882	60.93	gold quality
monocyte	CL:0000576	59.66	gold quality
putamen	UBERON:0001874	57.97	gold quality
calcaneal tendon	UBERON:0003701	57.46	gold quality
caudate nucleus	UBERON:0001873	57.17	gold quality
prefrontal cortex	UBERON:0000451	57.11	gold quality
muscle of leg	UBERON:0001383	56.11	gold quality
hypothalamus	UBERON:0001898	55.47	gold quality
islet of Langerhans	UBERON:0000006	53.55	gold quality
brain	UBERON:0000955	53.51	gold quality
substantia nigra	UBERON:0002038	53.10	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.28	gold quality
blood	UBERON:0000178	52.00	silver quality
gall bladder	UBERON:0002110	51.90	gold quality
gastrocnemius	UBERON:0001388	51.81	gold quality
primary visual cortex	UBERON:0002436	51.13	gold quality
myometrium	UBERON:0001296	51.12	silver quality
frontal cortex	UBERON:0001870	50.36	gold quality
lung	UBERON:0002048	49.71	gold quality
popliteal artery	UBERON:0002250	48.04	gold quality
tibial artery	UBERON:0007610	47.87	gold quality
cerebral cortex	UBERON:0000956	47.30	gold quality
adrenal tissue	UBERON:0018303	46.48	silver quality
superior frontal gyrus	UBERON:0002661	45.66	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	45.36	gold quality
Brodmann (1909) area 9	UBERON:0013540	45.24	gold quality
temporal lobe	UBERON:0001871	45.14	gold quality
amygdala	UBERON:0001876	44.92	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-HCAD-30	no	58.60
E-ANND-3	no	1.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.