ZFHX3-AS3

Summary

ZFHX3-AS3 (ZFHX3 antisense RNA 3, HGNC:58538) is a long non-coding RNA gene on chromosome 16q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58538
Approved symbol	ZFHX3-AS3
Name	ZFHX3 antisense RNA 3
Location	16q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261227
Ensembl biotype	lncRNA
Entrez	124903716

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000561802, ENST00000577171, ENST00000737029, ENST00000737030, ENST00000737031, ENST00000737032, ENST00000737033, ENST00000737034

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000561802 — 2 exons

Exon	Start	End
ENSE00004070896	73233884	73234261
ENSE00004070900	73232007	73232868

Expression profiles

Bgee: expression breadth broad, 100 present calls, max score 83.22.

Top tissues by expression

100 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	83.22	gold quality
cortex of kidney	UBERON:0001225	72.99	gold quality
stromal cell of endometrium	CL:0002255	71.74	gold quality
nucleus accumbens	UBERON:0001882	71.53	gold quality
putamen	UBERON:0001874	70.98	gold quality
right lobe of liver	UBERON:0001114	70.63	gold quality
liver	UBERON:0002107	68.15	gold quality
caudate nucleus	UBERON:0001873	68.12	gold quality
corpus callosum	UBERON:0002336	66.66	gold quality
amygdala	UBERON:0001876	65.42	gold quality
temporal lobe	UBERON:0001871	65.29	gold quality
hypothalamus	UBERON:0001898	65.18	gold quality
right adrenal gland	UBERON:0001233	63.87	gold quality
islet of Langerhans	UBERON:0000006	63.64	gold quality
kidney	UBERON:0002113	63.62	gold quality
brain	UBERON:0000955	63.56	gold quality
substantia nigra	UBERON:0002038	63.29	gold quality
smooth muscle tissue	UBERON:0001135	62.96	gold quality
prefrontal cortex	UBERON:0000451	62.84	gold quality
urinary bladder	UBERON:0001255	62.49	gold quality
tibial artery	UBERON:0007610	62.42	gold quality
anterior cingulate cortex	UBERON:0009835	62.24	gold quality
pancreas	UBERON:0001264	62.15	gold quality
popliteal artery	UBERON:0002250	62.00	gold quality
gall bladder	UBERON:0002110	61.88	gold quality
right ovary	UBERON:0002118	61.77	gold quality
thoracic mammary gland	UBERON:0005200	61.75	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	61.55	gold quality
omental fat pad	UBERON:0010414	61.43	gold quality
frontal cortex	UBERON:0001870	61.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.76

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.