ZFX-AS1

Summary

ZFX-AS1 (ZFX antisense RNA 1, HGNC:40617) is a long non-coding RNA gene on chromosome Xp22.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40617
Approved symbol	ZFX-AS1
Name	ZFX antisense RNA 1
Location	Xp22.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234230
Ensembl biotype	lncRNA
Entrez	100873922
RNAcentral	URS0000300AE9 — lncRNA, 417 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000427551

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000427551 — 3 exons

Exon	Start	End
ENSE00001664301	24148753	24148842
ENSE00001685516	24146225	24146451
ENSE00001764842	24149555	24149654

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 83.28.

FANTOM5 (CAGE): breadth broad, TPM avg 0.6103 / max 25.0981, expressed in 326 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
198744	0.4177	235
198743	0.1927	82

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.28	silver quality
colonic epithelium	UBERON:0000397	79.14	gold quality
bone marrow cell	CL:0002092	76.38	gold quality
ventricular zone	UBERON:0003053	74.13	gold quality
cortical plate	UBERON:0005343	71.02	gold quality
ganglionic eminence	UBERON:0004023	70.21	gold quality
skeletal muscle tissue	UBERON:0001134	65.07	gold quality
cerebellar hemisphere	UBERON:0002245	64.97	gold quality
cerebellar cortex	UBERON:0002129	64.77	gold quality
cerebellum	UBERON:0002037	64.68	gold quality
granulocyte	CL:0000094	64.24	gold quality
monocyte	CL:0000576	64.12	gold quality
leukocyte	CL:0000738	64.06	gold quality
muscle of leg	UBERON:0001383	63.67	gold quality
right hemisphere of cerebellum	UBERON:0014890	63.64	gold quality
gastrocnemius	UBERON:0001388	63.52	gold quality
bone marrow	UBERON:0002371	62.84	gold quality
right lung	UBERON:0002167	60.38	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	60.30	gold quality
lymph node	UBERON:0000029	59.46	gold quality
prostate gland	UBERON:0002367	59.30	gold quality
urinary bladder	UBERON:0001255	58.25	gold quality
blood	UBERON:0000178	57.95	gold quality
gall bladder	UBERON:0002110	57.64	gold quality
tibial artery	UBERON:0007610	57.62	gold quality
popliteal artery	UBERON:0002250	57.60	gold quality
vermiform appendix	UBERON:0001154	57.18	gold quality
liver	UBERON:0002107	57.05	gold quality
brain	UBERON:0000955	56.79	gold quality
lower esophagus	UBERON:0013473	56.66	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.89

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.