◎ Sugi Atlas

Atlas / Gene / ZGPAT

ZGPAT

gene
On this page

Also known as dJ583P15.3MGC44880FLJ14972ZC3HDC9ZC3H9GPATC6GPATCH6ZIP

Summary

ZGPAT (zinc finger CCCH-type and G-patch domain containing, HGNC:15948) is a protein-coding gene on chromosome 20q13.33, encoding Zinc finger CCCH-type with G patch domain-containing protein (Q8N5A5). Transcription repressor that specifically binds the 5’-GGAG[GA]A[GA]A-3’ consensus sequence.

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of epidermal growth factor-activated receptor activity and negative regulation of transcription by RNA polymerase II. Located in nucleoplasm and plasma membrane.

Source: NCBI Gene 84619 — RefSeq curated summary.

At a glance

  • GWAS associations: 24
  • Clinical variants (ClinVar): 88 total
  • Transcription factor: yes — 13 downstream targets (CollecTRI)
  • MANE Select transcript: NM_181485

Identifiers

Gene identifiers

FieldValue
HGNC IDHGNC:15948
Approved symbolZGPAT
Namezinc finger CCCH-type and G-patch domain containing
Location20q13.33
Locus typegene with protein product
StatusApproved
AliasesdJ583P15.3, MGC44880, FLJ14972, ZC3HDC9, ZC3H9, GPATC6, GPATCH6, ZIP
Ensembl geneENSG00000197114
Ensembl biotypeprotein_coding
OMIM619577
Entrez84619

Gene structure

Transcript identifiers

Ensembl transcripts: 29 — 24 protein_coding, 3 protein_coding_CDS_not_defined, 2 retained_intron

ENST00000328969, ENST00000355969, ENST00000357119, ENST00000369967, ENST00000431125, ENST00000448100, ENST00000468235, ENST00000472711, ENST00000477340, ENST00000478385, ENST00000484569, ENST00000878098, ENST00000878099, ENST00000878100, ENST00000878101, ENST00000878102, ENST00000878103, ENST00000878104, ENST00000878105, ENST00000878106, ENST00000878107, ENST00000939516, ENST00000939517, ENST00000939518, ENST00000939519, ENST00000939520, ENST00000939521, ENST00000964255, ENST00000964256

RefSeq mRNA: 5 — MANE Select: NM_181485 NM_001083113, NM_001195653, NM_001195654, NM_032527, NM_181485

CCDS: CCDS13534, CCDS13535, CCDS56203

Canonical transcript exons

ENST00000355969 — 7 exons

ExonStartEnd
ENSE000018162196373578163736142
ENSE000019396506370803963708118
ENSE000035359076373470563734824
ENSE000035461616373358763733739
ENSE000035672426373321963733352
ENSE000035777616373515963735564
ENSE000036784656370855363709164

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 94.77.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 16.3460 / max 223.1221, expressed in 1808 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter IDTPM avgSamples expressed
18584916.21201808
1858500.050913
1858510.04987
1858520.03326

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

TissueAnatomy IDExpression scoreQuality
right lobe of liverUBERON:000111494.77gold quality
liverUBERON:000210793.81gold quality
granulocyteCL:000009492.96gold quality
bloodUBERON:000017891.57gold quality
sural nerveUBERON:001548891.56gold quality
spleenUBERON:000210689.47gold quality
apex of heartUBERON:000209889.37gold quality
monocyteCL:000057689.09gold quality
leukocyteCL:000073888.99gold quality
mucosa of transverse colonUBERON:000499188.81gold quality
adult mammalian kidneyUBERON:000008288.28gold quality
lower esophagus mucosaUBERON:003583488.27gold quality
right hemisphere of cerebellumUBERON:001489088.02gold quality
cerebellar hemisphereUBERON:000224587.61gold quality
cerebellumUBERON:000203787.58gold quality
cerebellar cortexUBERON:000212987.53gold quality
bone marrowUBERON:000237187.53gold quality
right adrenal glandUBERON:000123387.43gold quality
left adrenal gland cortexUBERON:003582587.36gold quality
left adrenal glandUBERON:000123487.33gold quality
right adrenal gland cortexUBERON:003582787.21gold quality
lymph nodeUBERON:000002987.07gold quality
vermiform appendixUBERON:000115487.02gold quality
cortex of kidneyUBERON:000122587.01gold quality
muscle layer of sigmoid colonUBERON:003580587.00gold quality
right lobe of thyroid glandUBERON:000111986.86gold quality
body of stomachUBERON:000116186.82gold quality
fundus of stomachUBERON:000116086.81gold quality
small intestine Peyer’s patchUBERON:000345486.78gold quality
ectocervixUBERON:001224986.58gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

ExperimentMarker?Max mean expression
E-ANND-3yes2.91

Regulation

Is transcription factor: yes

Downstream targets (CollecTRI)

13 targets.

TargetRegulation
ADAM2
BIK
CYP11A1
EGFRRepression
HAMP
IFNB1
IL1B
IL2
IL6
KRAS
MRGPRF
RHO
YBEY

Literature-anchored findings (GeneRIF, showing 2)

  • sZIP, an alternative splice variant of ZIP, antagonizes transcription repression and growth inhibition by ZIP in liver neoplasms. (PMID:20233718)
  • Data suggest that ZIP, USP39, Prp24/p100/SART3, and Prp43 associate to form complex instrumental in spliceosome assembly; ZIP regulates pre-mRNA splicing of USP39 independent of RNA binding; stable 35S tri-snRNP particles are enriched in Cajal body. (USP39 = ubiquitin specific peptidase 39; SART3 = squamous cell carcinoma antigen recognised by T cells 3; Prp43 = RNA helicase Prp43) (PMID:28878014)

Cross-species orthologs

5 orthologs

OrganismSymbolGene ID
danio_reriozgpatENSDARG00000027403
mus_musculusZgpatENSMUSG00000027582
rattus_norvegicusZgpatENSRNOG00000014235
drosophila_melanogasterCG4709FBGN0032169
caenorhabditis_elegansWBGENE00016383

Paralogs (2): TFIP11 (ENSG00000100109), LIME1 (ENSG00000203896)

Protein

Protein identifiers

Zinc finger CCCH-type with G patch domain-containing protein — Q8N5A5 (reviewed: Q8N5A5)

Alternative names: G patch domain-containing protein 6, Zinc finger CCCH domain-containing protein 9, Zinc finger and G patch domain-containing protein

All UniProt accessions (4): A0A0S2Z5X3, A0A0S2Z6H0, Q8N5A5, X6RGY1

UniProt curated annotations — full annotation on UniProt →

Function. Transcription repressor that specifically binds the 5’-GGAG[GA]A[GA]A-3’ consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. Antagonizes the transcription repression by isoform 1 by competing for the binding of the NuRD complex. Does not bind DNA.

Subunit / interactions. Interacts with CHD4/Mi-2; the interaction is direct.

Subcellular location. Nucleus Nucleus.

Tissue specificity. Widely expressed.

Post-translational modifications. Ubiquitinated in case of infection by HIV-1, leading to its degradation. Ubiquitination is mediated by the CUL4A-RBX1-DDB1-DCAF1/VPRBP complex that is hijacked by HIV-1 via interaction between HIV-1 Vpr and DCAF1/VPRBP.

Induction. Down-regulated in breast carcinomas.

Isoforms (4)

UniProt IDNamesCanonical?
Q8N5A5-11yes
Q8N5A5-22
Q8N5A5-33
Q8N5A5-44, sZIP

RefSeq proteins (5): NP_001076582, NP_001182582, NP_001182583, NP_115916, NP_852150* (*=MANE)

Domains & families (InterPro)

IDNameType
IPR000467G_patch_domDomain
IPR000571Znf_CCCHDomain
IPR036855Znf_CCCH_sfHomologous_superfamily
IPR041367Znf-CCCH_4Domain

Pfam: PF01585, PF18044

UniProt features (36 total): strand 9, sequence conflict 5, region of interest 5, compositionally biased region 4, helix 4, splice variant 3, modified residue 2, chain 1, domain 1, sequence variant 1, zinc finger region 1

Structure

Experimental structures (PDB)

1 structures.

PDBMethodResolution (Å)
4II1X-RAY DIFFRACTION2.65

Predicted structure (AlphaFold)

ModelpLDDTFraction very-high
AF-Q8N5A5-F175.940.37

Functional residue map

Curated UniProt residues grouped by drug-discovery relevance — catalytic, ligand-binding, modification, and mutation-validated positions. Source: UniProtKB sequence features.

Post-translational modifications (2): 1, 373

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 103 (showing top): GOBP_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY, GOBP_NEGATIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION, GOBP_REGULATION_OF_ERBB_SIGNALING_PATHWAY, GOBP_REGULATION_OF_PHOSPHORYLATION, GOBP_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY, GNF2_GSTM1, GOBP_NEGATIVE_REGULATION_OF_ERBB_SIGNALING_PATHWAY, GNF2_HPN, GOZGIT_ESR1_TARGETS_DN, GOBP_NEGATIVE_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY, GOBP_REGULATION_OF_TRANSFERASE_ACTIVITY, CCATCCA_MIR432, GOBP_ERBB_SIGNALING_PATHWAY, GNF2_LCAT, GOBP_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS

GO Biological Process (3): negative regulation of transcription by RNA polymerase II (GO:0000122), negative regulation of epidermal growth factor-activated receptor activity (GO:0007175), negative regulation of DNA-templated transcription (GO:0045892)

GO Molecular Function (10): RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978), DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981), DNA-binding transcription repressor activity, RNA polymerase II-specific (GO:0001227), DNA-binding transcription factor activity (GO:0003700), zinc ion binding (GO:0008270), sequence-specific DNA binding (GO:0043565), nucleic acid binding (GO:0003676), DNA binding (GO:0003677), protein binding (GO:0005515), metal ion binding (GO:0046872)

GO Cellular Component (4): chromatin (GO:0000785), nucleus (GO:0005634), nucleoplasm (GO:0005654), plasma membrane (GO:0005886)

GO top-level categories

Rollup of top GO terms by namespace:

CategoryTerms
RNA polymerase II transcription regulatory region sequence-specific DNA binding3
regulation of transcription by RNA polymerase II2
regulation of DNA-templated transcription2
binding2
cellular anatomical structure2
transcription by RNA polymerase II1
negative regulation of DNA-templated transcription1
epidermal growth factor receptor activity1
negative regulation of epidermal growth factor receptor signaling pathway1
negative regulation of protein tyrosine kinase activity1
negative regulation of signaling receptor activity1
DNA-templated transcription1
negative regulation of RNA biosynthetic process1
cis-regulatory region sequence-specific DNA binding1
chromatin1
DNA-binding transcription factor activity1
negative regulation of transcription by RNA polymerase II1
DNA-binding transcription factor activity, RNA polymerase II-specific1
DNA-binding transcription repressor activity1
transcription cis-regulatory region binding1
transcription regulator activity1
transition metal ion binding1
DNA binding1
nucleic acid binding1
cation binding1
chromosome1
intracellular membrane-bounded organelle1
nuclear lumen1
membrane1
cell periphery1

Protein interactions and networks

STRING

1255 interactions, top by confidence (×1000):

Protein AProtein BPartner UniProtScore
ZGPATSLC2A4RGQ9NR83658
ZGPATARFRP1Q13795622
ZGPATLIME1Q9H400620
ZGPATFNDC11Q9BVV2533
ZGPATGMEB2Q9UKD1529
ZGPATSTMN3Q9NZ72523
ZGPATTMEM232C9JQI7506
ZGPATCHD4Q14839504
ZGPATEME1Q96AY2491
ZGPATZNF512BQ96KM6491
ZGPATMTA3Q9BTC8479
ZGPATOR10A3P58181477
ZGPATRTEL1Q9NZ71477
ZGPATMCM10Q7L590474
ZGPATSMUG1Q53HV7471

IntAct

151 interactions, top by confidence:

ABTypeScore
LSM3LSM1psi-mi:“MI:0914”(association)0.950
SNRPFGEMIN2psi-mi:“MI:0914”(association)0.910
PRPF3PRPF4psi-mi:“MI:0914”(association)0.730
SART3PRPF4psi-mi:“MI:0914”(association)0.730
DHX15ZGPATpsi-mi:“MI:0915”(physical association)0.670
ZGPATDHX15psi-mi:“MI:0915”(physical association)0.670
ZGPATCCNDBP1psi-mi:“MI:0915”(physical association)0.670
LDOC1ZGPATpsi-mi:“MI:0915”(physical association)0.670
TRIM27ZGPATpsi-mi:“MI:0915”(physical association)0.670
ZGPATTLE5psi-mi:“MI:0915”(physical association)0.670
CEP70ZGPATpsi-mi:“MI:0915”(physical association)0.670
KIFC3ZGPATpsi-mi:“MI:0915”(physical association)0.670
TFIP11ZGPATpsi-mi:“MI:0915”(physical association)0.670
SSX2IPZGPATpsi-mi:“MI:0915”(physical association)0.670
CCNDBP1ZGPATpsi-mi:“MI:0915”(physical association)0.670
ZGPATTRIM27psi-mi:“MI:0915”(physical association)0.670
ZGPATKIFC3psi-mi:“MI:0915”(physical association)0.670
ZGPATTFIP11psi-mi:“MI:0915”(physical association)0.670
ZGPATSSX2IPpsi-mi:“MI:0915”(physical association)0.670

BioGRID (251): ZGPAT (Two-hybrid), ZGPAT (Two-hybrid), ZGPAT (Two-hybrid), ZGPAT (Two-hybrid), ZGPAT (Two-hybrid), ZGPAT (Two-hybrid), ZGPAT (Two-hybrid), ZGPAT (Two-hybrid), ZGPAT (Two-hybrid), ZGPAT (Two-hybrid), ZGPAT (Two-hybrid), ZGPAT (Two-hybrid), ZGPAT (Two-hybrid), ZGPAT (Two-hybrid), ZGPAT (Two-hybrid)

ESM2 similar proteins: A1L131, A4IFK7, C5IJB0, D3ZND0, F1MX48, O60232, O95400, P35689, Q0VCT3, Q17QX2, Q2KIJ6, Q2YD98, Q3ZBK7, Q3ZBN4, Q4R4I0, Q53GS7, Q5EAN7, Q5FVK6, Q5PPF5, Q5RAS2, Q5T0F9, Q68F60, Q69ZT1, Q6AYI4, Q6NU18, Q6TLH3, Q7L4P6, Q7TMX5, Q8BL74, Q8BRN9, Q8BSI6, Q8C0R7, Q8C6D4, Q8N5A5, Q8R322, Q8VDM1, Q91VL8, Q91WA6, Q91WR3, Q969X0

Diamond homologs: A1XD93, A1XD94, A1XD95, A1XD97, A4UMC5, A4UMC6, A7SBN6, B3MPC0, B3N8L3, B4G7U3, B4HWD7, B4JCG4, B4KH32, B4M9F7, B4NYQ2, B4Q8A7, C0HAV3, C5IJB0, P10265, P63119, P63121, P63123, P63124, P63125, P63129, P63131, P70501, P98175, Q06411, Q06AK6, Q0IIX9, Q17784, Q17CQ8, Q17QX2, Q28H71, Q29NF3, Q29RR5, Q5PPF5, Q5R5K8, Q5U2Y6

SIGNOR signaling

0 interactions.

Enriched among interaction partners

Reactome pathways and GO biological processes over-represented among this gene’s 98 IntAct physical interaction partners (hypergeometric vs the genome-wide background, BH-FDR, gene-set size 15–500, ranked by fold). A functional readout of the neighbourhood — distinct from this gene’s own memberships above, and biased toward well-studied / hub proteins, so read it as themes rather than proof.

Reactome pathways:

PathwayPartnersFoldFDR
mRNA Splicing814.9×1e-05
Processing of Capped Intron-Containing Pre-mRNA811.1×5e-05
mRNA Splicing - Major Pathway1211.1×2e-07
CHD1 and CHD2 subfamily59.2×8e-03
Metabolism of RNA117.8×2e-05

GO biological processes:

GO termPartnersFoldFDR
spliceosomal snRNP assembly640.5×2e-06
RNA splicing, via transesterification reactions536.3×3e-05
mRNA splicing, via spliceosome1212.8×9e-08
RNA splicing1010.3×9e-06

Disease & clinical

Clinical variants and AI predictions

ClinVar

88 variants total. Per-class counts are floors (≥ shown; pagination cap):

ClassificationCount (floor)
Pathogenic0
Likely pathogenic0
Uncertain significance70
Likely benign9
Benign0

Top pathogenic / likely-pathogenic (0)

SpliceAI

1635 predictions. Top by Δscore:

VariantEffectΔscore
20:63733578:T:TAacceptor_gain1.0000
20:63733584:CAGA:Cacceptor_loss1.0000
20:63733585:A:AGacceptor_gain1.0000
20:63733585:A:Cacceptor_loss1.0000
20:63733586:G:GGacceptor_gain1.0000
20:63733586:GAT:Gacceptor_gain1.0000
20:63733586:GATGT:Gacceptor_gain1.0000
20:63733737:GAG:Gdonor_gain1.0000
20:63733772:G:GTdonor_gain1.0000
20:63734703:A:AGacceptor_gain1.0000
20:63734703:AGT:Aacceptor_gain1.0000
20:63734704:G:GAacceptor_gain1.0000
20:63734704:GTG:Gacceptor_gain1.0000
20:63735539:G:GTdonor_gain1.0000
20:63735560:GGCCG:Gdonor_gain1.0000
20:63735561:GCCG:Gdonor_gain1.0000
20:63735561:GCCGG:Gdonor_gain1.0000
20:63735563:CGGT:Cdonor_loss1.0000
20:63735565:G:GGdonor_gain1.0000
20:63735565:G:Tdonor_loss1.0000
20:63735566:T:Adonor_loss1.0000
20:63708066:G:GTdonor_gain0.9900
20:63708552:GCCCT:Gacceptor_gain0.9900
20:63708803:G:GTdonor_gain0.9900
20:63708809:GC:Gdonor_gain0.9900
20:63708810:C:Gdonor_gain0.9900
20:63733218:G:GTacceptor_loss0.9900
20:63733322:G:GTdonor_gain0.9900
20:63733351:CGG:Cdonor_loss0.9900
20:63733352:GGTGA:Gdonor_loss0.9900

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000061453 (20:63716278 C>T), RS1000219937 (20:63728546 C>T), RS1000321575 (20:63733426 C>T), RS1000333953 (20:63728850 C>T), RS1000445426 (20:63706232 C>T), RS1000499086 (20:63732734 GTC>G), RS1000543965 (20:63735691 C>A,G,T), RS1000563134 (20:63705472 A>G), RS1000608168 (20:63733285 C>T), RS1000679114 (20:63710067 A>C,G), RS1000746717 (20:63711167 C>T), RS1000783491 (20:63720645 G>A,T), RS1000796253 (20:63714978 G>A), RS1000847544 (20:63721954 A>G), RS1000918676 (20:63706149 C>T)

Disease associations

OMIM: gene MIM:619577 | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

24 associations (top):

StudyTraitp-value
GCST000964_24Ulcerative colitis2.000000e-10
GCST001725_68Inflammatory bowel disease1.000000e-23
GCST001942_22Prostate cancer4.000000e-16
GCST004131_34Inflammatory bowel disease3.000000e-26
GCST004132_110Crohn’s disease3.000000e-13
GCST004133_15Ulcerative colitis9.000000e-17
GCST004183_22Lung function (FEV1)4.000000e-13
GCST006479_16Diverticular disease8.000000e-06
GCST007563_15Allergic disease (asthma, hay fever or eczema)3.000000e-08
GCST007564_6Asthma or allergic disease (pleiotropy)3.000000e-10
GCST007614_5C-reactive protein levels5.000000e-10
GCST007876_130Estimated glomerular filtration rate2.000000e-09
GCST008059_155Estimated glomerular filtration rate4.000000e-11
GCST008860_30Prostate cancer4.000000e-06
GCST008916_69Asthma3.000000e-09
GCST010002_71Refractive error1.000000e-14
GCST010658_21High density lipoprotein cholesterol levels3.000000e-06
GCST010659_5Waist circumference5.000000e-06
GCST012232_38Lipoprotein (a) levels4.000000e-11
GCST90002389_428Lymphocyte percentage of white cells7.000000e-20
GCST90002398_61Neutrophil count2.000000e-13
GCST90002399_460Neutrophil percentage of white cells9.000000e-16
GCST90002400_309Plateletcrit3.000000e-14
GCST90002402_603Platelet count2.000000e-15

EFO canonical traits (10, from GWAS)

EFO IDTrait name
EFO:0004314forced expiratory volume
EFO:0009959diverticular disease
EFO:0004458C-reactive protein measurement
EFO:0004612high density lipoprotein cholesterol measurement
EFO:0006925lipoprotein A measurement
EFO:0007993lymphocyte percentage of leukocytes
EFO:0004833neutrophil count
EFO:0007990neutrophil percentage of leukocytes
EFO:0007985platelet crit
EFO:0004309platelet count

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

36 total (human), top 30 by PubMed support.

ChemicalActions (top 5)PubMed papers
Air Pollutantsincreases oxidation, affects expression, affects cotreatment, increases abundance2
Ozoneaffects cotreatment, increases oxidation, increases abundance, affects expression2
FR900359affects phosphorylation1
testosterone enanthateaffects expression1
triphenyl phosphateaffects expression1
alpha-pineneaffects cotreatment, increases oxidation, increases abundance1
pirinixic acidaffects binding, decreases expression, increases activity1
beta-lapachoneincreases expression1
sodium arsenitedecreases expression1
perfluorooctanoic aciddecreases expression1
methacrylaldehydeaffects cotreatment, increases oxidation, increases abundance1
beta-methylcholineaffects expression1
perfluorooctane sulfonic aciddecreases expression1
2,3,5-(triglutathion-S-yl)hydroquinoneincreases ADP-ribosylation1
CGP 52608affects binding, increases reaction1
perfluoro-n-nonanoic aciddecreases expression1
perfluorohexanesulfonic aciddecreases expression1
abrineincreases expression1
bisphenol Saffects cotreatment, decreases expression1
Bortezomibincreases expression1
Sunitinibdecreases expression1
Acetaminophendecreases expression1
Acroleinaffects cotreatment, increases oxidation, increases abundance1
Caffeineincreases phosphorylation1
Dexamethasoneaffects cotreatment, decreases expression1
Diazinonincreases methylation1
Indomethacindecreases expression, affects cotreatment1
Smokedecreases expression1
Valproic Acidincreases methylation, decreases expression1
1-Methyl-3-isobutylxanthineaffects cotreatment, decreases expression1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.

No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.

About this page

Generated deterministically by Sugi Atlas from primary biomedical databases via BioBTree. Every record on this page traces to a primary source.

Generated
Atlas version
v1.1.4
BioBTree
v2.0.2

Sources 74

This page pulls from 74 datasets indexed by BioBTree:

alphafoldalphamissenseantibodybgeebgee_evidencebindingdbbiogrid_interactionbrendabrenda_kineticsccdscellosauruschembl_activitychembl_targetciviccivic_evidenceclingen_dosageclingen_gene_validityclinical_trialsclinvarcollectrictd_gene_interactiondbsnpdepmapdiamond_similarityefoensemblentrezesm2_similarityexonfantom5_genefantom5_promotergenccgenerifgogoparentgtopdbgwasgwas_studyhgnchpointactinterprointogenjasparmeshmimmirdbmondomsigdborphanetorthologparalogpdbpfampharmgkb_clinicalpharmgkb_genepharmgkb_guidelinepharmgkb_variantpubchempubchem_activitypubchem_assaypubmedreactomerefseqrhearnacentralscxa_expressionscxa_gene_experimentsignorspliceaistring_interactiontranscriptufeatureuniprot