ZIC4-AS1

Summary

ZIC4-AS1 (ZIC4 antisense RNA 1, HGNC:40920) is a long non-coding RNA gene on chromosome 3q24.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40920
Approved symbol	ZIC4-AS1
Name	ZIC4 antisense RNA 1
Location	3q24
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000241202
Ensembl biotype	lncRNA
Entrez	100873950
RNAcentral	URS00025E3553 — lncRNA, 1826 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000462168

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000462168 — 2 exons

Exon	Start	End
ENSE00004141484	147386965	147387099
ENSE00004141485	147387319	147387614

Expression profiles

Bgee: expression breadth broad, 64 present calls, max score 68.59.

Top tissues by expression

64 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skeletal muscle tissue	UBERON:0001134	68.59	gold quality
prefrontal cortex	UBERON:0000451	61.30	gold quality
blood	UBERON:0000178	60.18	gold quality
sural nerve	UBERON:0015488	59.02	silver quality
frontal cortex	UBERON:0001870	58.46	gold quality
primary visual cortex	UBERON:0002436	57.67	gold quality
right lobe of liver	UBERON:0001114	57.25	gold quality
cerebral cortex	UBERON:0000956	57.08	gold quality
muscle of leg	UBERON:0001383	56.07	gold quality
mucosa of stomach	UBERON:0001199	56.03	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	55.85	gold quality
gastrocnemius	UBERON:0001388	55.54	gold quality
cerebellum	UBERON:0002037	55.48	gold quality
cerebellar cortex	UBERON:0002129	55.28	gold quality
cerebellar hemisphere	UBERON:0002245	55.16	gold quality
putamen	UBERON:0001874	54.78	gold quality
Brodmann (1909) area 9	UBERON:0013540	54.65	gold quality
right hemisphere of cerebellum	UBERON:0014890	54.28	gold quality
anterior cingulate cortex	UBERON:0009835	53.70	gold quality
heart left ventricle	UBERON:0002084	53.51	gold quality
left coronary artery	UBERON:0001626	53.11	gold quality
adipose tissue	UBERON:0001013	51.85	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	51.46	gold quality
subcutaneous adipose tissue	UBERON:0002190	51.36	gold quality
nucleus accumbens	UBERON:0001882	51.01	gold quality
multicellular organism	UBERON:0000468	50.73	gold quality
substantia nigra	UBERON:0002038	50.62	gold quality
hypothalamus	UBERON:0001898	50.57	gold quality
tibial artery	UBERON:0007610	50.54	gold quality
right frontal lobe	UBERON:0002810	50.45	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.