ZIM2-AS1

Summary

ZIM2-AS1 (ZIM2 antisense RNA 1, HGNC:51304) is a long non-coding RNA gene on chromosome 19q13.43.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51304
Approved symbol	ZIM2-AS1
Name	ZIM2 antisense RNA 1
Location	19q13.43
Locus type	RNA, long non-coding
Status	Approved
Aliases	ZIM2as
Ensembl gene	ENSG00000269793
Ensembl biotype	lncRNA
Entrez	101929059
RNAcentral	URS000075B358 — lncRNA, 2151 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000650950

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000650950 — 6 exons

Exon	Start	End
ENSE00003813642	56709799	56709856
ENSE00003842386	56797993	56799602
ENSE00003843432	56595313	56595428
ENSE00003843537	56667277	56667428
ENSE00003847702	56601507	56601591
ENSE00003849808	56684301	56684371

Expression profiles

Bgee: expression breadth broad, 89 present calls, max score 64.02.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3157 / max 57.4145, expressed in 140 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
177730	6.0921	1566
177735	0.3157	140

Top tissues by expression

89 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ganglionic eminence	UBERON:0004023	64.02	gold quality
cortex of kidney	UBERON:0001225	57.25	gold quality
prefrontal cortex	UBERON:0000451	55.06	gold quality
blood	UBERON:0000178	51.04	gold quality
islet of Langerhans	UBERON:0000006	50.17	silver quality
superior frontal gyrus	UBERON:0002661	49.92	gold quality
frontal cortex	UBERON:0001870	49.26	gold quality
monocyte	CL:0000576	49.21	silver quality
Brodmann (1909) area 9	UBERON:0013540	48.55	gold quality
primary visual cortex	UBERON:0002436	47.60	silver quality
cerebral cortex	UBERON:0000956	47.57	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	47.09	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	47.00	silver quality
anterior cingulate cortex	UBERON:0009835	46.83	gold quality
temporal lobe	UBERON:0001871	46.80	gold quality
amygdala	UBERON:0001876	46.46	gold quality
cerebellum	UBERON:0002037	46.00	silver quality
brain	UBERON:0000955	45.94	gold quality
Ammon’s horn	UBERON:0001954	45.77	gold quality
cerebellar cortex	UBERON:0002129	45.70	silver quality
hypothalamus	UBERON:0001898	45.65	gold quality
right frontal lobe	UBERON:0002810	45.65	gold quality
cerebellar hemisphere	UBERON:0002245	45.50	silver quality
muscle of leg	UBERON:0001383	45.18	silver quality
putamen	UBERON:0001874	44.68	gold quality
right hemisphere of cerebellum	UBERON:0014890	44.67	gold quality
gastrocnemius	UBERON:0001388	44.40	silver quality
nucleus accumbens	UBERON:0001882	44.16	gold quality
multicellular organism	UBERON:0000468	43.99	gold quality
substantia nigra	UBERON:0002038	43.91	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.23

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.