ZKSCAN7-AS1

Summary

ZKSCAN7-AS1 (ZKSCAN7 ZNF cluster antisense RNA 1, HGNC:53964) is a long non-coding RNA gene on chromosome 3p21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53964
Approved symbol	ZKSCAN7-AS1
Name	ZKSCAN7 ZNF cluster antisense RNA 1
Location	3p21.31
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-944L7.4
Ensembl gene	ENSG00000236869
Ensembl biotype	lncRNA
Entrez	112840933
RNAcentral	URS00004011EB — lncRNA, 456 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 18 — 18 lncRNA

ENST00000447691, ENST00000457331, ENST00000685649, ENST00000701041, ENST00000715681, ENST00000725156, ENST00000725157, ENST00000725158, ENST00000725159, ENST00000725160, ENST00000725161, ENST00000725162, ENST00000725163, ENST00000725164, ENST00000725165, ENST00000725166, ENST00000725167, ENST00000725168

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000447691 — 2 exons

Exon	Start	End
ENSE00004048507	44616236	44617674
ENSE00004048517	44624722	44624955

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 84.86.

FANTOM5 (CAGE): breadth broad, TPM avg 0.6128 / max 54.2742, expressed in 281 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
41860	0.6128	281

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.86	gold quality
apex of heart	UBERON:0002098	76.47	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	74.27	gold quality
cortical plate	UBERON:0005343	74.00	gold quality
ventricular zone	UBERON:0003053	73.68	gold quality
bone marrow cell	CL:0002092	71.14	silver quality
heart left ventricle	UBERON:0002084	71.04	gold quality
ganglionic eminence	UBERON:0004023	69.94	gold quality
right atrium auricular region	UBERON:0006631	69.27	gold quality
smooth muscle tissue	UBERON:0001135	69.24	gold quality
heart	UBERON:0000948	69.07	gold quality
islet of Langerhans	UBERON:0000006	68.70	gold quality
skeletal muscle tissue	UBERON:0001134	68.68	gold quality
stromal cell of endometrium	CL:0002255	68.19	gold quality
muscle of leg	UBERON:0001383	65.41	gold quality
prefrontal cortex	UBERON:0000451	65.25	gold quality
gastrocnemius	UBERON:0001388	64.96	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.83	gold quality
colonic epithelium	UBERON:0000397	64.78	silver quality
putamen	UBERON:0001874	64.75	gold quality
gall bladder	UBERON:0002110	64.07	gold quality
right uterine tube	UBERON:0001302	63.74	gold quality
rectum	UBERON:0001052	63.72	gold quality
caudate nucleus	UBERON:0001873	63.51	gold quality
primary visual cortex	UBERON:0002436	63.40	gold quality
cortex of kidney	UBERON:0001225	63.34	gold quality
nucleus accumbens	UBERON:0001882	63.30	gold quality
fallopian tube	UBERON:0003889	63.09	gold quality
cerebellum	UBERON:0002037	63.03	gold quality
cerebellar cortex	UBERON:0002129	62.93	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.23

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.