ZNF225-AS1

Summary

ZNF225-AS1 (ZNF225 and ZNF224 antisense RNA 1, HGNC:55916) is a long non-coding RNA gene on chromosome 19q13.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55916
Approved symbol	ZNF225-AS1
Name	ZNF225 and ZNF224 antisense RNA 1
Location	19q13.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000186019
Ensembl biotype	lncRNA
Entrez	100379224
RNAcentral	URS000075D51A — lncRNA, 3361 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000590369, ENST00000592946, ENST00000661725, ENST00000685371

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000590369 — 2 exons

Exon	Start	End
ENSE00004103863	44111950	44112239
ENSE00004103865	44112822	44113176

Expression profiles

Bgee: expression breadth ubiquitous, 157 present calls, max score 81.62.

Top tissues by expression

245 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	81.62	gold quality
ganglionic eminence	UBERON:0004023	77.29	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.42	gold quality
ventricular zone	UBERON:0003053	73.45	gold quality
bone marrow cell	CL:0002092	71.57	silver quality
prefrontal cortex	UBERON:0000451	70.46	gold quality
islet of Langerhans	UBERON:0000006	70.25	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.38	gold quality
stromal cell of endometrium	CL:0002255	67.74	gold quality
cerebellar cortex	UBERON:0002129	66.54	gold quality
cerebellar hemisphere	UBERON:0002245	66.49	gold quality
kidney epithelium	UBERON:0004819	66.35	gold quality
hypothalamus	UBERON:0001898	66.33	gold quality
anterior cingulate cortex	UBERON:0009835	65.61	gold quality
neocortex	UBERON:0001950	65.59	gold quality
right hemisphere of cerebellum	UBERON:0014890	65.53	gold quality
sural nerve	UBERON:0015488	65.52	silver quality
frontal cortex	UBERON:0001870	65.43	gold quality
cerebellum	UBERON:0002037	65.37	gold quality
caudate nucleus	UBERON:0001873	65.35	gold quality
colonic epithelium	UBERON:0000397	65.22	silver quality
nucleus accumbens	UBERON:0001882	65.01	gold quality
Brodmann (1909) area 9	UBERON:0013540	64.59	gold quality
right frontal lobe	UBERON:0002810	64.57	gold quality
adenohypophysis	UBERON:0002196	64.28	gold quality
adrenal tissue	UBERON:0018303	64.03	gold quality
putamen	UBERON:0001874	63.94	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	63.77	gold quality
heart left ventricle	UBERON:0002084	63.48	gold quality
cerebral cortex	UBERON:0000956	63.33	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.58

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.