ZNF236

gene
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Summary

ZNF236 (zinc finger protein 236, HGNC:13028) is a protein-coding gene on chromosome 18q23, encoding Zinc finger protein 236 (Q9UL36). May be involved in transcriptional regulation. It is a selective cancer dependency (DepMap: 17.4% of cell lines).

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cellular response to glucose stimulus. Predicted to be active in nucleus.

Source: NCBI Gene 7776 — RefSeq curated summary.

At a glance

  • GWAS associations: 6
  • Clinical variants (ClinVar): 279 total
  • Cancer dependency (DepMap): dependent in 17.4% of screened cell lines
  • Transcription factor: yes — 14 downstream targets (CollecTRI)
  • MANE Select transcript: NM_001306089

Identifiers

Gene identifiers

FieldValue
HGNC IDHGNC:13028
Approved symbolZNF236
Namezinc finger protein 236
Location18q23
Locus typegene with protein product
StatusApproved
Ensembl geneENSG00000130856
Ensembl biotypeprotein_coding
OMIM604760
Entrez7776

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 3 protein_coding, 2 nonsense_mediated_decay, 2 retained_intron, 2 protein_coding_CDS_not_defined

ENST00000253159, ENST00000320610, ENST00000543926, ENST00000579322, ENST00000583095, ENST00000583488, ENST00000584565, ENST00000645888, ENST00000706008

RefSeq mRNA: 2 — MANE Select: NM_001306089 NM_001306089, NM_007345

CCDS: CCDS42447, CCDS77201

Canonical transcript exons

ENST00000320610 — 31 exons

ExonStartEnd
ENSE000008949187685177576851939
ENSE000008949377687800976878152
ENSE000008949397688011376880316
ENSE000011794967687549276875664
ENSE000011795027687170176871825
ENSE000012807147691066076910811
ENSE000012807247691006876910169
ENSE000012807327690832076908573
ENSE000012807457690438076904521
ENSE000012807577689501376895285
ENSE000012808567691224476912347
ENSE000012808867690515576905415
ENSE000012808987689901976899222
ENSE000012994907692727776927517
ENSE000013007897692518976925554
ENSE000013090837691977676920058
ENSE000013255017692307176923174
ENSE000013267247692703776927182
ENSE000013306687692792776928106
ENSE000013830337684952676849668
ENSE000027023147682255776822662
ENSE000027123727696821576972901
ENSE000034615707686868576868863
ENSE000034718557693715676937343
ENSE000035219817695968776959816
ENSE000035697807695598576956182
ENSE000035916097696067976960855
ENSE000036098267691374776913898
ENSE000036262437688128476881512
ENSE000036805877691564776915859
ENSE000036904427694752176947652

Expression profiles

Bgee: expression breadth ubiquitous, 277 present calls, max score 93.08.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 2.3388 / max 22.3062, expressed in 1209 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter IDTPM avgSamples expressed
1708032.33881209

Top tissues by expression

287 total, by Bgee expression score (0-100, higher = more expressed):

TissueAnatomy IDExpression scoreQuality
sural nerveUBERON:001548893.08gold quality
gingival epitheliumUBERON:000194992.83gold quality
calcaneal tendonUBERON:000370192.83gold quality
buccal mucosa cellCL:000233692.69silver quality
germinal epithelium of ovaryUBERON:000130491.58gold quality
male germ line stem cell (sensu Vertebrata) in testisCL:0000089 ∩ UBERON:000047388.60gold quality
mucosa of urinary bladderUBERON:000125988.36gold quality
primordial germ cell in gonadCL:0000670 ∩ UBERON:000099188.35gold quality
corpus callosumUBERON:000233687.35gold quality
olfactory bulbUBERON:000226485.20silver quality
mucosa of paranasal sinusUBERON:000503085.19gold quality
type B pancreatic cellCL:000016984.68gold quality
gingivaUBERON:000182884.25gold quality
superficial temporal arteryUBERON:000161484.16gold quality
hair follicleUBERON:000207383.99silver quality
tendonUBERON:000004383.34gold quality
epithelium of nasopharynxUBERON:000195182.16gold quality
diaphragmUBERON:000110382.06gold quality
tibiaUBERON:000097982.00gold quality
visceral pleuraUBERON:000240181.79gold quality
pleuraUBERON:000097781.18gold quality
medial globus pallidusUBERON:000247780.36gold quality
parietal pleuraUBERON:000240080.25gold quality
adrenal tissueUBERON:001830379.96gold quality
cortical plateUBERON:000534379.50gold quality
bone marrow cellCL:000209279.47gold quality
thymusUBERON:000237079.17gold quality
tonsilUBERON:000237278.67gold quality
globus pallidusUBERON:000187577.90gold quality
epithelial cell of pancreasCL:000008377.80silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

ExperimentMarker?Max mean expression
E-ANND-3no5.79

Regulation

Is transcription factor: yes

Downstream targets (CollecTRI)

14 targets.

TargetRegulation
ADH1B
CHMP4A
CSNK2A2
CXCL9
FERMT2
GCGR
INS
MAPK3
NEUROD1
PC
PDX1
PKLR
SLC2A2
VPS4B

miRNA regulators (miRDB)

226 targeting ZNF236, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNAMax scoreAvg scoremiRNA target_count
HSA-MIR-3163100.0077.238605
HSA-MIR-5692A100.0074.406850
HSA-LET-7A-3P100.0074.033932
HSA-LET-7B-3P100.0074.083913
HSA-LET-7F-1-3P100.0074.023928
HSA-MIR-98-3P100.0074.083907
HSA-MIR-190A-3P100.0080.355520
HSA-MIR-6740-5P100.0065.64932
HSA-MIR-340-5P100.0072.504437
HSA-MIR-9-5P100.0072.282361
HSA-MIR-3613-3P100.0076.367965
HSA-MIR-656-3P100.0072.152788
HSA-MIR-4795-3P100.0074.624024
HSA-MIR-5011-5P100.0083.465820
HSA-MIR-1252-5P100.0069.802774
HSA-MIR-4682100.0068.891258
HSA-MIR-366299.9973.825684
HSA-MIR-196A-1-3P99.9972.152772
HSA-MIR-428299.9975.366408
HSA-MIR-513B-5P99.9969.962150
HSA-MIR-548C-3P99.9974.017587
HSA-MIR-477599.9875.006394
HSA-MIR-1213699.9872.815713
HSA-MIR-520D-5P99.9873.344883
HSA-MIR-524-5P99.9873.434882
HSA-MIR-314899.9775.066478
HSA-MIR-548AN99.9770.912817
HSA-MIR-302C-5P99.9772.563642
HSA-MIR-60799.9773.625593
HSA-MIR-3065-5P99.9771.563281

Functional genomics

DepMap (CRISPR cell-line fitness): dependent in 17.4% of screened cell lines.

Cross-species orthologs

4 orthologs

OrganismSymbolGene ID
danio_rerioznf236ENSDARG00000095890
mus_musculusZfp236ENSMUSG00000041258
rattus_norvegicusZfp236ENSRNOG00000016303
drosophila_melanogasterCG15073FBGN0034379

Protein

Protein identifiers

Zinc finger protein 236Q9UL36 (reviewed: Q9UL36)

All UniProt accessions (4): Q9UL36, A0A2R8YCW3, A0A994J512, J9JID5

UniProt curated annotations — full annotation on UniProt →

Function. May be involved in transcriptional regulation.

Subcellular location. Nucleus.

Tissue specificity. Ubiquitous. Expression levels are highest in skeletal muscle and brain, intermediate in heart, pancreas, and placenta, and lowest in kidney, liver, and lung.

Miscellaneous. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Similarity. Belongs to the krueppel C2H2-type zinc-finger protein family.

Isoforms (2)

UniProt IDNamesCanonical?
Q9UL36-1Byes
Q9UL36-2A

RefSeq proteins (2): NP_001293018, NP_031371 (=MANE)

Domains & families (InterPro)

IDNameType
IPR013087Znf_C2H2_typeDomain
IPR036236Znf_C2H2_sfHomologous_superfamily
IPR051643Transcr_Reg_ZincFingerFamily

Pfam: PF00096, PF12874, PF13465, PF13912

UniProt features (45 total): zinc finger region 30, sequence variant 5, region of interest 3, compositionally biased region 3, splice variant 2, chain 1, sequence conflict 1

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

ModelpLDDTFraction very-high
AF-Q9UL36-F155.210.04

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 161 (showing top): GSE45365_NK_CELL_VS_CD8A_DC_UP, GSE45365_NK_CELL_VS_BCELL_UP, LEE_NEURAL_CREST_STEM_CELL_DN, TGCACTT_MIR519C_MIR519B_MIR519A, AAGCCAT_MIR135A_MIR135B, GOBP_CELLULAR_RESPONSE_TO_CARBOHYDRATE_STIMULUS, GCAAGGA_MIR502, TATTATA_MIR374, GOBP_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND, BLALOCK_ALZHEIMERS_DISEASE_UP, ACATTCC_MIR1_MIR206, GOBP_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND, PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP, GOBP_INTRACELLULAR_GLUCOSE_HOMEOSTASIS, GOBP_CARBOHYDRATE_HOMEOSTASIS

GO Biological Process (2): regulation of transcription by RNA polymerase II (GO:0006357), cellular response to glucose stimulus (GO:0071333)

GO Molecular Function (6): RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978), DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981), zinc ion binding (GO:0008270), DNA binding (GO:0003677), protein binding (GO:0005515), metal ion binding (GO:0046872)

GO Cellular Component (1): nucleus (GO:0005634)

GO top-level categories

Rollup of top GO terms by namespace:

CategoryTerms
RNA polymerase II transcription regulatory region sequence-specific DNA binding2
regulation of DNA-templated transcription1
transcription by RNA polymerase II1
intracellular glucose homeostasis1
response to glucose1
cellular response to hexose stimulus1
cis-regulatory region sequence-specific DNA binding1
chromatin1
DNA-binding transcription factor activity1
regulation of transcription by RNA polymerase II1
transition metal ion binding1
nucleic acid binding1
binding1
cation binding1
intracellular membrane-bounded organelle1

Protein interactions and networks

STRING

1075 interactions, top by confidence (×1000):

Protein AProtein BPartner UniProtScore
ZNF236CAPN15O75808480
ZNF236CCAR2Q8N163477
ZNF236MLLT3P42568456
ZNF236GALR1P47211454
ZNF236MED8Q96G25443
ZNF236ETV7Q9Y603426
ZNF236FOXP2O15409422
ZNF236ZNF594Q96JF6417
ZNF236CA8P35219416
ZNF236TFB2MQ9H5Q4406
ZNF236PTGR3Q8N4Q0397
ZNF236TRDNQ13061379
ZNF236PPANQ9NQ55373
ZNF236DOT1LQ8TEK3369
ZNF236MAMLD1Q13495366

IntAct

5 interactions, top by confidence:

ABTypeScore
PRKAB2ZNF236psi-mi:“MI:0915”(physical association)0.560
KRR1PES1psi-mi:“MI:0914”(association)0.350

BioGRID (12): ZNF236 (Affinity Capture-MS), ZNF236 (Affinity Capture-RNA), ZNF236 (Two-hybrid), ZNF236 (Affinity Capture-RNA), ZNF236 (Affinity Capture-RNA), PRKAB2 (Two-hybrid), ZNF236 (Positive Genetic), ZNF236 (Affinity Capture-MS), ZNF236 (Affinity Capture-MS), ZNF236 (Affinity Capture-RNA), ZNF236 (Affinity Capture-RNA), ZNF236 (Cross-Linking-MS (XL-MS))

ESM2 similar proteins: A0JPB4, A1L1J6, A4IFJ6, D3ZUU2, E9Q8T2, G5E8B9, O08954, O15060, O42409, O43623, O57415, O70237, O75626, O95625, P19382, P25932, P36197, P37275, P97469, Q20082, Q2EI20, Q3MHQ4, Q3UH06, Q4VBD9, Q5DU09, Q5R9W9, Q5SVQ8, Q5T0B9, Q5ZLR2, Q60542, Q60636, Q62947, Q64318, Q6DCW1, Q6GNP2, Q6INV8, Q6NRM0, Q7TS63, Q7ZVR6, Q80X44

Diamond homologs: A0A9P4XV22, A2ANX9, B1H2Q6, O62836, P08048, P0CJ78, P10925, P17010, P17012, P20662, P27705, P28698, P52288, P80944, Q01611, Q03081, Q03125, Q0VDT2, Q29419, Q3U3I9, Q52V16, Q567C6, Q5U2Z0, Q6B4Z5, Q7RTV3, Q95LI3, Q966L8, Q96EG3, Q9UDV6, Q9UL36, Q9Y462, B0K011, B0X9H6, E9Q6W4, O75362, O77459, P31509, P60319, P86413, Q01798

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

279 variants total. Per-class counts are floors (≥ shown; pagination cap):

ClassificationCount (floor)
Pathogenic0
Likely pathogenic0
Uncertain significance207
Likely benign23
Benign13

Top pathogenic / likely-pathogenic (0)

SpliceAI

5749 predictions. Top by Δscore:

VariantEffectΔscore
18:76849512:AT:Aacceptor_gain1.0000
18:76849513:T:Gacceptor_gain1.0000
18:76849513:T:TAacceptor_gain1.0000
18:76849516:A:AGacceptor_gain1.0000
18:76849524:A:AGacceptor_gain1.0000
18:76849524:AGAT:Aacceptor_gain1.0000
18:76849525:G:GGacceptor_gain1.0000
18:76849525:GATG:Gacceptor_gain1.0000
18:76849669:G:GGdonor_gain1.0000
18:76851769:A:AGacceptor_gain1.0000
18:76851770:A:Gacceptor_gain1.0000
18:76851773:A:AGacceptor_gain1.0000
18:76851774:G:GAacceptor_gain1.0000
18:76851774:GCC:Gacceptor_gain1.0000
18:76851774:GCCAC:Gacceptor_gain1.0000
18:76851934:G:GTdonor_gain1.0000
18:76868682:CAGA:Cacceptor_loss1.0000
18:76868683:A:AGacceptor_gain1.0000
18:76868683:A:Cacceptor_loss1.0000
18:76868684:G:GAacceptor_gain1.0000
18:76868684:GA:Gacceptor_gain1.0000
18:76868843:G:GTdonor_gain1.0000
18:76868863:GGTA:Gdonor_gain1.0000
18:76871696:ACTAG:Aacceptor_gain1.0000
18:76871822:ACAG:Adonor_loss1.0000
18:76871823:CAG:Cdonor_loss1.0000
18:76871824:AG:Adonor_loss1.0000
18:76871825:GGTAT:Gdonor_loss1.0000
18:76871826:G:GAdonor_loss1.0000
18:76871827:T:Adonor_loss1.0000

AlphaMissense

12232 scored. Top likely-pathogenic:

VariantProtein changeam_pathogenicity
18:76851784:T:CC68R1.000
18:76851793:T:CC71R1.000
18:76851824:T:CL81P1.000
18:76871759:T:CC199R1.000
18:76871807:C:GH215D1.000
18:76871809:C:AH215Q1.000
18:76871809:C:GH215Q1.000
18:76875509:T:CC227R1.000
18:76875518:T:CC230R1.000
18:76875530:T:CF234L1.000
18:76875531:T:CF234S1.000
18:76875532:T:AF234L1.000
18:76875532:T:GF234L1.000
18:76875538:G:CQ236H1.000
18:76875538:G:TQ236H1.000
18:76875549:T:CL240P1.000
18:76875557:C:GH243D1.000
18:76875559:C:AH243Q1.000
18:76875559:C:GH243Q1.000
18:76875593:T:CC255R1.000
18:76875594:G:AC255Y1.000
18:76875595:T:GC255W1.000
18:76875602:T:CC258R1.000
18:76875603:G:AC258Y1.000
18:76875604:T:GC258W1.000
18:76875614:T:CF262L1.000
18:76875615:T:CF262S1.000
18:76875616:C:AF262L1.000
18:76875616:C:GF262L1.000
18:76875633:T:CL268P1.000

dbSNP variants (sampled 300 via entrez): RS1000048008 (18:76862900 A>G), RS1000054036 (18:76958673 T>C), RS1000060421 (18:76936476 T>C), RS1000078624 (18:76862699 A>G), RS1000121419 (18:76949701 C>A), RS1000141812 (18:76906749 A>C), RS1000147061 (18:76891215 T>A), RS1000151766 (18:76888350 G>A,C), RS1000154712 (18:76876692 A>C), RS1000159020 (18:76869849 G>A), RS1000171031 (18:76829396 C>T), RS1000205416 (18:76844198 C>T), RS1000208101 (18:76953402 C>T), RS1000218471 (18:76931559 G>A,T), RS1000228140 (18:76823789 C>A,T)

Disease associations

OMIM: gene MIM:604760 | disease phenotypes:

GenCC curated gene-disease

Mondo (1): neurodevelopmental disorder (MONDO:0700092)

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

6 associations (top):

StudyTraitp-value
GCST002007_4Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)2.000000e-06
GCST002701_38Verbal declarative memory2.000000e-06
GCST004863_86Mosquito bite size6.000000e-06
GCST009391_1470Metabolite levels1.000000e-06
GCST009391_1826Metabolite levels6.000000e-06
GCST011320_34Type 2 diabetes or prostate cancer (pleiotropy)2.000000e-08

EFO canonical traits (5, from GWAS)

EFO IDTrait name
EFO:0004874memory performance
EFO:0006805word list delayed recall measurement
EFO:0008378mosquito bite reaction size measurement
EFO:0010407triacylglycerol 48:4 measurement
EFO:0010411triacylglycerol 50:4 measurement

MeSH disease descriptors (1)

DescriptorNameTree numbers
D065886Neurodevelopmental DisordersF03.625

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

22 total (human), top 22 by PubMed support.

ChemicalActions (top 5)PubMed papers
Phenylmercuric Acetateaffects cotreatment, decreases expression2
aristolochic acid Idecreases expression1
methylmercuric chloridedecreases expression1
triphenyl phosphateaffects expression1
beta-lapachonedecreases expression, increases expression1
butyraldehydedecreases expression1
cupric oxideincreases expression1
CGP 52608affects binding, increases reaction1
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamidedecreases expression, affects cotreatment1
dorsomorphinaffects cotreatment, decreases expression1
Sunitinibincreases expression1
Amphotericin Bincreases expression1
Arsenicaffects methylation1
Benzo(a)pyreneincreases methylation1
Cadmiumdecreases expression, increases abundance1
Carbamazepineaffects expression1
Formaldehydedecreases expression1
Hydrogen Peroxidedecreases expression1
Valproic Aciddecreases methylation1
Aflatoxin B1decreases methylation1
Cadmium Chloridedecreases expression, increases abundance1
Copper Sulfateincreases expression1

Clinical trials (associated diseases)

202 trials via MONDO — disease-level, not drug-specific.

TrialPhaseStatusTitle
NCT04586348PHASE4UNKNOWNPrenatal Iodine Supplementation and Early Childhood Neurodevelopment
NCT04873115PHASE4UNKNOWNDouble-blind, Placebo-controlled, Randomized Clinical Trial Comparing the Efficacy and Safety of Sialanar Plus orAl rehabiLitation Against Placebo Plus Oral Rehabilitation for chIldren and Adolescents With seVere Sialorrhoea and Neurodisabilties,
NCT02559102PHASE3COMPLETEDDexmedetomidine Sedation Versus General Anaesthesia for Inguinal Hernia Surgery in Infants
NCT02757079PHASE3COMPLETEDStudy of the Efficacy and Safety of NPC-15 for Sleep Disorders of Children With Neurodevelopmental Disorders
NCT06915480PHASE3RECRUITINGReducing Missed Appointments
NCT07377032PHASE3RECRUITINGTAP-GRIN: Interventional Study on Patients With GRIN-related Neurodevelopmental Disorders
NCT02909959PHASE2COMPLETEDSulforaphane for the Treatment of Young Men With Autism Spectrum Disorder
NCT06081348PHASE2RECRUITINGSertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders
NCT06352372PHASE2COMPLETEDSafety and Efficacy of tPBM for Epileptiform Activity in Autism
NCT00503191PHASE1COMPLETEDNeuroModulation Technique Treatment of Autism
NCT04475848PHASE1COMPLETEDA Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of RO6953958 in Healthy Participants
NCT06300398PHASE1COMPLETEDIAMA-6 Oral Dose Study in Healthy Adults
NCT01783041PHASE2/PHASE3COMPLETEDEffect of Early L-Carnitine Supplementation on Neurodevelopmental Outcomes in Very Preterm Infants
NCT05767385PHASE2/PHASE3RECRUITINGFetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior
NCT05675098EARLY_PHASE1NOT_YET_RECRUITINGCentral Nervous System Stimulants and Physical Function in Children With Cerebral Palsy
NCT00783783Not specifiedCOMPLETEDCYP2D6 Pharmacogenetics in Risperidone-Treated Children
NCT01778504Not specifiedRECRUITINGStudying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders
NCT01850784Not specifiedUNKNOWNHigh Energy Formula Feeding in Infants With Congenital Heart Disease
NCT01922791Not specifiedCOMPLETEDNutrition and Pregnancy Intervention Study
NCT01942525Not specifiedUNKNOWNInfluence of Intrauterine Growth Restriction on Amplitude-integrated EEG in Preterm Infants
NCT02003170Not specifiedCOMPLETEDEtiology and Early Diagnosis of Neurodevelopmental Disorders
NCT02118649Not specifiedACTIVE_NOT_RECRUITINGEnhancing Behavior and Brain Response to Visual Targets Using a Computer Game
NCT02557191Not specifiedTERMINATEDBiomarkers, Neurodevelopment and Preterm Infants
NCT02690675Not specifiedCOMPLETEDIron Supplement Effect on Child Development
NCT02694003Not specifiedCOMPLETEDBetter Nights, Better Days for Children With Neurodevelopment Disorders
NCT02792894Not specifiedCOMPLETEDFamily Networks (FaNs) for Children With Developmental Disorders and Delays
NCT02871674Not specifiedUNKNOWNGood Night Project: Behavioural Sleep Interventions for Children With ADHD: A Randomised Controlled Trial
NCT02887157Not specifiedCOMPLETEDAnalyzing Retinal Microanatomy in ROP
NCT02898298Not specifiedCOMPLETEDPositive Emotion Regulation Training in Children, Adolescents and Young Adults With and Without Developmental Disorder
NCT02912780Not specifiedUNKNOWNIntroduction of Microsystems in a Level 3 Neonatal Intensive Care Unit
NCT03023293Not specifiedCOMPLETEDn-3 PUFAs, Irisin and Maternal Glucose Metabolism From Pregnancy to Postpartum
NCT03023644Not specifiedCOMPLETEDImproving Neurodevelopmental Outcomes in Children With Congenital Heart Disease: An Intervention Study
NCT03032991Not specifiedUNKNOWNEarly Biomarkers of Neurodevelopment in Offspring of Diabetic Mothers
NCT03088189Not specifiedTERMINATEDEffect of Parental Peri-conceptional Vitamin B12 Supplementation on Infant Neurocognitive Development in Offspring
NCT03096028Not specifiedCOMPLETEDDevelopmental Origins of Mental Health Disorders
NCT03148782Not specifiedCOMPLETEDBrain Plasticity Underlying Acquisition of New Organizational Skills in Children-R61 Phase
NCT03172104Not specifiedCOMPLETEDNeurobehavioural Development of Infants Born <30 Weeks Gestational Age Between Birth and Five Years of Age
NCT03222375Not specifiedRECRUITINGSQUED™ Series 28.1 Home-use and Treatment of Autowave Reverberator of Autism
NCT03229928Not specifiedCOMPLETEDClinical Testing of a Real-Time Behavior Measurement Tool: Measuring Outcomes for CHAnge
NCT03232489Not specifiedUNKNOWNStudy for the Evaluation of the Feasibility of Applying Advanced MRI Scanning in Pediatric Clinical Practice
  • Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): prostate carcinoma