ZNF248-AS1

Summary

ZNF248-AS1 (ZNF248 antisense RNA 1, HGNC:56681) is a long non-coding RNA gene on chromosome 10p11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56681
Approved symbol	ZNF248-AS1
Name	ZNF248 antisense RNA 1
Location	10p11.21
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-162G10.5
Ensembl gene	ENSG00000236514
Ensembl biotype	lncRNA
Entrez	128266837
RNAcentral	URS00026A1EF2 — lncRNA, 2342 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000429214

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000429214 — 2 exons

Exon	Start	End
ENSE00001751637	37859078	37859110
ENSE00001770629	37857740	37858532

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 73.45.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	73.45	gold quality
bone marrow cell	CL:0002092	70.15	silver quality
right uterine tube	UBERON:0001302	69.15	gold quality
skeletal muscle tissue	UBERON:0001134	63.84	gold quality
stromal cell of endometrium	CL:0002255	63.59	gold quality
cortical plate	UBERON:0005343	63.11	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.98	gold quality
ventricular zone	UBERON:0003053	61.47	gold quality
bone marrow	UBERON:0002371	61.08	gold quality
ganglionic eminence	UBERON:0004023	60.80	gold quality
apex of heart	UBERON:0002098	59.41	gold quality
urinary bladder	UBERON:0001255	58.72	gold quality
granulocyte	CL:0000094	58.22	gold quality
fallopian tube	UBERON:0003889	58.22	gold quality
skin of leg	UBERON:0001511	58.13	gold quality
thyroid gland	UBERON:0002046	58.08	gold quality
right lobe of thyroid gland	UBERON:0001119	58.04	gold quality
zone of skin	UBERON:0000014	57.96	gold quality
right adrenal gland	UBERON:0001233	57.88	gold quality
left lobe of thyroid gland	UBERON:0001120	57.83	gold quality
skin of abdomen	UBERON:0001416	57.69	gold quality
right adrenal gland cortex	UBERON:0035827	57.59	gold quality
vermiform appendix	UBERON:0001154	57.45	gold quality
lymph node	UBERON:0000029	57.44	gold quality
muscle layer of sigmoid colon	UBERON:0035805	57.31	gold quality
adrenal gland	UBERON:0002369	57.27	gold quality
liver	UBERON:0002107	57.23	gold quality
left adrenal gland	UBERON:0001234	57.22	gold quality
right lobe of liver	UBERON:0001114	56.96	gold quality
duodenum	UBERON:0002114	56.95	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.23

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• H3K27 acetylation activated long noncoding RNA RP11-162G10.5 promotes breast cancer progression via the YBX1/GLO1 axis. (PMID:36576700)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.