ZNF25-DT

Summary

ZNF25-DT (ZNF25 divergent transcript, HGNC:54109) is a long non-coding RNA gene on chromosome 10p11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54109
Approved symbol	ZNF25-DT
Name	ZNF25 divergent transcript
Location	10p11.21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226447
Ensembl biotype	lncRNA
Entrez	105376499
RNAcentral	URS0002A1FC07 — lncRNA, 1106 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000412789, ENST00000722137, ENST00000722138, ENST00000722139, ENST00000722140, ENST00000722141, ENST00000722142

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412789 — 3 exons

Exon	Start	End
ENSE00001780395	37980289	37980410
ENSE00004042468	37976798	37977005
ENSE00004042474	37992327	37992563

Expression profiles

Bgee: expression breadth broad, 61 present calls, max score 93.71.

Top tissues by expression

61 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	93.71	gold quality
left testis	UBERON:0004533	73.41	gold quality
testis	UBERON:0000473	73.00	gold quality
right testis	UBERON:0004534	72.98	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	65.37	gold quality
blood	UBERON:0000178	57.27	gold quality
prefrontal cortex	UBERON:0000451	57.27	gold quality
islet of Langerhans	UBERON:0000006	57.10	gold quality
granulocyte	CL:0000094	56.82	gold quality
multicellular organism	UBERON:0000468	56.19	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.08	gold quality
gall bladder	UBERON:0002110	54.44	gold quality
monocyte	CL:0000576	54.24	gold quality
lymph node	UBERON:0000029	53.37	gold quality
right lobe of liver	UBERON:0001114	51.50	gold quality
gastrocnemius	UBERON:0001388	49.98	gold quality
thoracic aorta	UBERON:0001515	48.72	gold quality
heart left ventricle	UBERON:0002084	48.45	gold quality
tibial artery	UBERON:0007610	47.75	gold quality
ascending aorta	UBERON:0001496	47.26	gold quality
thyroid gland	UBERON:0002046	46.88	gold quality
body of pancreas	UBERON:0001150	46.27	gold quality
left lobe of thyroid gland	UBERON:0001120	45.85	gold quality
tibial nerve	UBERON:0001323	45.85	gold quality
fundus of stomach	UBERON:0001160	45.83	gold quality
lower esophagus muscularis layer	UBERON:0035833	45.70	gold quality
stomach	UBERON:0000945	45.43	gold quality
Brodmann (1909) area 9	UBERON:0013540	45.11	gold quality
body of stomach	UBERON:0001161	44.99	silver quality
left adrenal gland cortex	UBERON:0035825	44.84	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.86

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.