ZNF252P-AS1

Summary

ZNF252P-AS1 (ZNF252P antisense RNA 1, HGNC:27821) is a long non-coding RNA gene on chromosome 8q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27821
Approved symbol	ZNF252P-AS1
Name	ZNF252P antisense RNA 1
Location	8q24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255559
Ensembl biotype	lncRNA
Entrez	286103
RNAcentral	URS000075D0B3 — lncRNA, 3250 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000527067, ENST00000734270, ENST00000734271, ENST00000734272, ENST00000734273

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000527067 — 1 exons

Exon	Start	End
ENSE00002185566	145002811	145006046

Expression profiles

Bgee: expression breadth ubiquitous, 147 present calls, max score 69.46.

Top tissues by expression

229 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
oviduct epithelium	UBERON:0004804	69.46	gold quality
right uterine tube	UBERON:0001302	68.98	gold quality
adrenal tissue	UBERON:0018303	63.46	gold quality
ventricular zone	UBERON:0003053	59.61	silver quality
duodenum	UBERON:0002114	58.68	gold quality
mucosa of transverse colon	UBERON:0004991	58.59	gold quality
germinal epithelium of ovary	UBERON:0001304	57.88	silver quality
right adrenal gland cortex	UBERON:0035827	57.85	gold quality
right hemisphere of cerebellum	UBERON:0014890	57.65	gold quality
left adrenal gland cortex	UBERON:0035825	57.62	gold quality
fallopian tube	UBERON:0003889	57.47	gold quality
left adrenal gland	UBERON:0001234	57.44	gold quality
cerebellar hemisphere	UBERON:0002245	57.39	gold quality
cerebellar cortex	UBERON:0002129	57.24	gold quality
metanephros cortex	UBERON:0010533	57.05	gold quality
adrenal gland	UBERON:0002369	56.71	gold quality
ganglionic eminence	UBERON:0004023	56.63	silver quality
apex of heart	UBERON:0002098	56.52	gold quality
adrenal cortex	UBERON:0001235	56.44	gold quality
cerebellum	UBERON:0002037	56.07	gold quality
right adrenal gland	UBERON:0001233	56.02	gold quality
body of pancreas	UBERON:0001150	55.64	gold quality
spleen	UBERON:0002106	54.95	gold quality
stromal cell of endometrium	CL:0002255	54.61	silver quality
body of stomach	UBERON:0001161	54.07	gold quality
pancreas	UBERON:0001264	53.68	gold quality
sural nerve	UBERON:0015488	53.20	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	53.05	gold quality
calcaneal tendon	UBERON:0003701	53.00	silver quality
lymph node	UBERON:0000029	52.97	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.07

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• Down-regulation of ZNF252P-AS1 alleviates ovarian cancer progression by binding miR-324-3p to downregulate LY6K. (PMID:34980214)
• LncRNA-ZNF252P-AS1/miR-15b-5p promotes the proliferation of keloid fibroblast by regulating the BTF3-STAT3 signaling pathway. (PMID:36641250)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.