ZNF337-AS1

Summary

ZNF337-AS1 (ZNF337 antisense RNA 1, HGNC:40759) is a long non-coding RNA gene on chromosome 20p11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40759
Approved symbol	ZNF337-AS1
Name	ZNF337 antisense RNA 1
Location	20p11.21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000213742
Ensembl biotype	lncRNA
Entrez	102724826
RNAcentral	URS00007E3D08 — lncRNA, 1516 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 26 — 26 lncRNA

ENST00000414393, ENST00000420803, ENST00000421829, ENST00000428254, ENST00000439498, ENST00000455791, ENST00000661376, ENST00000700978, ENST00000701006, ENST00000772092, ENST00000772093, ENST00000772094, ENST00000772095, ENST00000772096, ENST00000772097, ENST00000772098, ENST00000772099, ENST00000772100, ENST00000772101, ENST00000772102, ENST00000772103, ENST00000772104, ENST00000772105, ENST00000772106, ENST00000772107, ENST00000772108

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000414393 — 5 exons

Exon	Start	End
ENSE00001592577	25634729	25634827
ENSE00001608313	25632158	25632288
ENSE00001643032	25624045	25624135
ENSE00001657092	25673852	25678074
ENSE00001744538	25634049	25634170

Expression profiles

Bgee: expression breadth ubiquitous, 136 present calls, max score 90.57.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 5.0361 / max 47.5917, expressed in 1632 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
183941	2.8271	1253
183940	1.2055	836
183939	1.0035	553

Top tissues by expression

138 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
thymus	UBERON:0002370	90.57	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.43	gold quality
right hemisphere of cerebellum	UBERON:0014890	81.31	gold quality
cerebellar hemisphere	UBERON:0002245	81.00	gold quality
cerebellar cortex	UBERON:0002129	80.95	gold quality
cerebellum	UBERON:0002037	80.68	gold quality
right uterine tube	UBERON:0001302	79.73	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.42	gold quality
pituitary gland	UBERON:0000007	79.39	gold quality
endometrium	UBERON:0001295	79.18	gold quality
adenohypophysis	UBERON:0002196	79.02	gold quality
left ovary	UBERON:0002119	78.24	gold quality
ovary	UBERON:0000992	77.86	gold quality
right ovary	UBERON:0002118	77.25	gold quality
lower esophagus muscularis layer	UBERON:0035833	76.95	gold quality
lower esophagus	UBERON:0013473	76.94	gold quality
cortical plate	UBERON:0005343	76.60	gold quality
right lobe of liver	UBERON:0001114	76.48	gold quality
cortex of kidney	UBERON:0001225	76.39	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	76.29	gold quality
right adrenal gland cortex	UBERON:0035827	76.07	gold quality
right adrenal gland	UBERON:0001233	75.93	gold quality
thyroid gland	UBERON:0002046	75.85	gold quality
right lobe of thyroid gland	UBERON:0001119	75.80	gold quality
colonic epithelium	UBERON:0000397	75.75	gold quality
muscle layer of sigmoid colon	UBERON:0035805	75.73	gold quality
body of uterus	UBERON:0009853	75.61	gold quality
left lobe of thyroid gland	UBERON:0001120	75.56	gold quality
mucosa of stomach	UBERON:0001199	75.29	gold quality
liver	UBERON:0002107	75.11	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.71

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.