ZNF34

Summary

ZNF34 (zinc finger protein 34, HGNC:13098) is a protein-coding gene on chromosome 8q24.3, encoding Zinc finger protein 34 (Q8IZ26). May be involved in transcriptional regulation.

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm.

Source: NCBI Gene 80778 — RefSeq curated summary.

At a glance

• GWAS associations: 6
• Clinical variants (ClinVar): 71 total
• MANE Select transcript: NM_001286769

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:13098
Approved symbol	ZNF34
Name	zinc finger protein 34
Location	8q24.3
Locus type	gene with protein product
Status	Approved
Aliases	KOX32
Ensembl gene	ENSG00000196378
Ensembl biotype	protein_coding
OMIM	194526
Entrez	80778

Gene structure

Transcript identifiers

Ensembl transcripts: 39 — 38 protein_coding, 1 retained_intron

ENST00000343459, ENST00000429371, ENST00000527740, ENST00000534337, ENST00000534445, ENST00000714360, ENST00000714361, ENST00000714362, ENST00000714363, ENST00000714364, ENST00000714365, ENST00000714366, ENST00000714367, ENST00000714368, ENST00000714369, ENST00000870740, ENST00000870741, ENST00000870742, ENST00000870743, ENST00000870744, ENST00000870745, ENST00000870746, ENST00000870747, ENST00000924812, ENST00000924813, ENST00000924814, ENST00000924815, ENST00000924816, ENST00000924817, ENST00000924818, ENST00000924819, ENST00000965277, ENST00000965278, ENST00000965279, ENST00000965280, ENST00000965281, ENST00000965282, ENST00000965283, ENST00000965284

RefSeq mRNA: 6 — MANE Select: NM_001286769 NM_001286769, NM_001286770, NM_001378027, NM_001378028, NM_001378029, NM_030580

CCDS: CCDS69562

Canonical transcript exons

ENST00000429371 — 6 exons

Exon	Start	End
ENSE00001372181	144777458	144777577
ENSE00001648939	144787279	144787317
ENSE00002395826	144778038	144778164
ENSE00002733376	144780228	144780280
ENSE00003596553	144778439	144778525
ENSE00003902455	144772224	144774605

Expression profiles

Bgee: expression breadth ubiquitous, 203 present calls, max score 84.91.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 2.7080 / max 45.4777, expressed in 1282 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
95714	2.6839	1276
95710	0.0241	5

Top tissues by expression

274 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
tibial artery	UBERON:0007610	84.91	gold quality
popliteal artery	UBERON:0002250	84.90	gold quality
cerebellar hemisphere	UBERON:0002245	84.31	gold quality
right hemisphere of cerebellum	UBERON:0014890	84.24	gold quality
cerebellar cortex	UBERON:0002129	84.19	gold quality
cerebellum	UBERON:0002037	82.88	gold quality
cortical plate	UBERON:0005343	82.49	gold quality
aorta	UBERON:0000947	82.28	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.01	gold quality
ganglionic eminence	UBERON:0004023	81.89	gold quality
mucosa of stomach	UBERON:0001199	80.39	gold quality
tibial nerve	UBERON:0001323	80.13	gold quality
descending thoracic aorta	UBERON:0002345	80.01	gold quality
endocervix	UBERON:0000458	79.94	gold quality
muscle layer of sigmoid colon	UBERON:0035805	79.94	gold quality
left uterine tube	UBERON:0001303	79.79	gold quality
left ovary	UBERON:0002119	79.76	gold quality
right coronary artery	UBERON:0001625	79.69	gold quality
calcaneal tendon	UBERON:0003701	79.59	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	79.57	gold quality
body of uterus	UBERON:0009853	79.40	gold quality
lower esophagus muscularis layer	UBERON:0035833	79.40	gold quality
lower esophagus	UBERON:0013473	79.34	gold quality
left coronary artery	UBERON:0001626	79.31	gold quality
ventricular zone	UBERON:0003053	79.27	gold quality
thoracic aorta	UBERON:0001515	79.18	gold quality
ascending aorta	UBERON:0001496	79.08	gold quality
right ovary	UBERON:0002118	78.71	gold quality
adenohypophysis	UBERON:0002196	78.54	gold quality
ectocervix	UBERON:0012249	78.49	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.80

Regulation

Is transcription factor: no

miRNA regulators (miRDB)

59 targeting ZNF34, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNA	Max score	Avg score	miRNA target_count
HSA-MIR-4795-3P	100.00	74.62	4024
HSA-MIR-3925-3P	100.00	69.95	1237
HSA-MIR-6833-3P	100.00	70.63	3197
HSA-MIR-3662	99.99	73.82	5684
HSA-MIR-12136	99.98	72.81	5713
HSA-MIR-5696	99.98	72.36	4487
HSA-MIR-8068	99.98	73.85	2376
HSA-MIR-3658	99.96	73.87	4379
HSA-MIR-570-3P	99.96	72.41	4910
HSA-MIR-128-3P	99.95	71.17	2484
HSA-MIR-216A-3P	99.95	71.19	2505
HSA-MIR-338-5P	99.92	72.34	2951
HSA-MIR-4302	99.89	67.94	1187
HSA-MIR-3140-3P	99.88	68.47	2069
HSA-MIR-3681-3P	99.88	70.46	2254
HSA-MIR-4698	99.84	71.41	4303
HSA-MIR-4495	99.82	72.08	3080
HSA-MIR-3121-3P	99.82	71.96	3630
HSA-MIR-1299	99.77	71.24	2389
HSA-MIR-6794-5P	99.76	66.38	1048
HSA-MIR-4524A-3P	99.72	66.85	2406
HSA-MIR-4716-3P	99.69	66.73	1022
HSA-MIR-4729	99.69	72.18	4233
HSA-MIR-5093	99.67	69.26	2291
HSA-MIR-4743-3P	99.62	68.12	2095
HSA-MIR-4672	99.50	71.58	2893
HSA-MIR-3915	99.45	68.49	1905
HSA-MIR-4762-3P	99.43	69.72	2363
HSA-MIR-513A-3P	99.39	70.63	3620
HSA-MIR-513C-3P	99.39	70.63	3620

Literature-anchored findings (GeneRIF, showing 1)

• genes encoding transcription factors expressed in the brain might be an important group of major depressive disorder candidate genes. (PMID:26823146)

Cross-species orthologs

39 orthologs

Organism	Symbol	Gene ID
mus_musculus	Zfp944	ENSMUSG00000033972
mus_musculus	Gm21411	ENSMUSG00000045699
mus_musculus	Zfp943	ENSMUSG00000053347
mus_musculus	Zfp981	ENSMUSG00000056300
mus_musculus	Zfp980	ENSMUSG00000058186
mus_musculus	Zfp945	ENSMUSG00000059142
mus_musculus	Zfp534	ENSMUSG00000062518
mus_musculus	Zfp993	ENSMUSG00000063245
mus_musculus	Zfp947	ENSMUSG00000063383
mus_musculus	Zfp985	ENSMUSG00000065999
mus_musculus	Zfp979	ENSMUSG00000066000
mus_musculus	Zfp987	ENSMUSG00000066009
mus_musculus	Zfp991	ENSMUSG00000067916
mus_musculus	Rex2	ENSMUSG00000067919
mus_musculus	Zfp760	ENSMUSG00000067928
mus_musculus	Zfp820	ENSMUSG00000069743
mus_musculus	Zfp992	ENSMUSG00000070605
mus_musculus	Zfp946	ENSMUSG00000071266
mus_musculus	Zfp942	ENSMUSG00000071267
mus_musculus	Zfp984	ENSMUSG00000078495
mus_musculus	Zfp978	ENSMUSG00000078497
mus_musculus	Zfp988	ENSMUSG00000078498
mus_musculus	Zfp990	ENSMUSG00000078503
mus_musculus	Zfp995	ENSMUSG00000078546
mus_musculus	Zfp989	ENSMUSG00000086147
mus_musculus	Zfp994	ENSMUSG00000096433
mus_musculus	Gm7072	ENSMUSG00000117284
rattus_norvegicus	Zfp943	ENSRNOG00000026569
rattus_norvegicus	Zfp945l1	ENSRNOG00000028767
rattus_norvegicus	Zfp534l2	ENSRNOG00000033792
rattus_norvegicus	AABR07001923.1	ENSRNOG00000047884
rattus_norvegicus	Zfp600	ENSRNOG00000051867
rattus_norvegicus	Rex2l4	ENSRNOG00000059160
rattus_norvegicus	Zfp945	ENSRNOG00000061533
rattus_norvegicus	Rex2l2	ENSRNOG00000062461
rattus_norvegicus	Zfp534l1	ENSRNOG00000063088
rattus_norvegicus		ENSRNOG00000065823
rattus_norvegicus		ENSRNOG00000066546
rattus_norvegicus		ENSRNOG00000068796

Paralogs (51): WIZ (ENSG00000011451), ZNF416 (ENSG00000083817), MYNN (ENSG00000085274), PRDM4 (ENSG00000110851), PRDM2 (ENSG00000116731), ZBTB17 (ENSG00000116809), ZNF644 (ENSG00000122482), GZF1 (ENSG00000125812), ZNF426 (ENSG00000130818), ZNF287 (ENSG00000141040), ZNF697 (ENSG00000143067), ZNF687 (ENSG00000143373), ZNF214 (ENSG00000149050), ZNF547 (ENSG00000152433), ZNF776 (ENSG00000152443), ZNF230 (ENSG00000159882), ZNF222 (ENSG00000159885), ZNF233 (ENSG00000159915), ZNF333 (ENSG00000160961), ZNF319 (ENSG00000166188), ZNF592 (ENSG00000166716), ZNF646 (ENSG00000167395), ZNF507 (ENSG00000168813), ZNF768 (ENSG00000169957), ZNF417 (ENSG00000173480), ZNF408 (ENSG00000175213), ZBTB41 (ENSG00000177888), ZNF223 (ENSG00000178386), ZNF852 (ENSG00000178917), ZNF784 (ENSG00000179922), ZNF572 (ENSG00000180938), ZNF707 (ENSG00000181135), ZNF746 (ENSG00000181220), ZNF467 (ENSG00000181444), ZNF530 (ENSG00000183647), ZNF17 (ENSG00000186272), ZNF527 (ENSG00000189164), ZKSCAN7 (ENSG00000196345), ZNF774 (ENSG00000196391), ZNF777 (ENSG00000196453)

Protein

Protein identifiers

Zinc finger protein 34 — Q8IZ26 (reviewed: Q8IZ26)

Alternative names: Zinc finger protein KOX32

All UniProt accessions (3): A0A0C4DG42, Q8IZ26, E9PNZ6

UniProt curated annotations — full annotation on UniProt →

Function. May be involved in transcriptional regulation.

Subcellular location. Nucleus.

Similarity. Belongs to the krueppel C2H2-type zinc-finger protein family.

RefSeq proteins (6): NP_001273698, NP_001273699, NP_001364956, NP_001364957, NP_001364958, NP_085057 (=MANE)

Domains & families (InterPro)

ID	Name	Type
IPR001909	KRAB	Domain
IPR013087	Znf_C2H2_type	Domain
IPR036051	KRAB_dom_sf	Homologous_superfamily
IPR036236	Znf_C2H2_sf	Homologous_superfamily
IPR050589	Ikaros_C2H2-ZF	Family

Pfam: PF00096, PF01352

UniProt features (16 total): zinc finger region 12, chain 1, domain 1, region of interest 1, modified residue 1

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Model	pLDDT	Fraction very-high
AF-Q8IZ26-F1	70.46	0.18

Functional residue map

Curated UniProt residues grouped by drug-discovery relevance — catalytic, ligand-binding, modification, and mutation-validated positions. Source: UniProtKB sequence features.

Post-translational modifications (1): 113

Function

Pathways and Gene Ontology

Reactome pathways

1 pathways

ID	Pathway
R-HSA-212436	Generic Transcription Pathway

MSigDB gene sets: 79 (showing top): GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_MCMV_INFECTION_UP, SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A5, PARENT_MTOR_SIGNALING_UP, KIM_WT1_TARGETS_DN, NIKOLSKY_BREAST_CANCER_8Q23_Q24_AMPLICON, GOMF_SEQUENCE_SPECIFIC_DNA_BINDING, MARTENS_TRETINOIN_RESPONSE_UP, chr8q24, MTOR_UP.N4.V1_DN, GOMF_TRANSCRIPTION_REGULATOR_ACTIVITY, EBNA1BP2_TARGET_GENES, GUCY1B1_TARGET_GENES, SETD7_TARGET_GENES, SFMBT1_TARGET_GENES, SNRNP70_TARGET_GENES

GO Biological Process (2): regulation of transcription by RNA polymerase II (GO:0006357), regulation of DNA-templated transcription (GO:0006355)

GO Molecular Function (6): RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978), DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981), zinc ion binding (GO:0008270), DNA binding (GO:0003677), protein binding (GO:0005515), metal ion binding (GO:0046872)

GO Cellular Component (3): nucleus (GO:0005634), nucleoplasm (GO:0005654), cytosol (GO:0005829)

Reactome top-level categories

Rollup of top-1 pathways:

Category	Pathways
RNA Polymerase II Transcription	1

GO top-level categories

Rollup of top GO terms by namespace:

Category	Terms
RNA polymerase II transcription regulatory region sequence-specific DNA binding	2
cellular anatomical structure	2
regulation of DNA-templated transcription	1
transcription by RNA polymerase II	1
DNA-templated transcription	1
regulation of gene expression	1
regulation of RNA biosynthetic process	1
cis-regulatory region sequence-specific DNA binding	1
chromatin	1
DNA-binding transcription factor activity	1
regulation of transcription by RNA polymerase II	1
transition metal ion binding	1
nucleic acid binding	1
binding	1
cation binding	1
intracellular membrane-bounded organelle	1
nuclear lumen	1
cytoplasm	1

Protein interactions and networks

STRING

476 interactions, top by confidence (×1000):

Protein A	Protein B	Partner UniProt	Score
ZNF34	NKPD1	Q17RQ9	584
ZNF34	ARMH2	H3BNL8	570
ZNF34	MROH1	Q8NDA8	474
ZNF34	ZMYND12	Q9H0C1	449
ZNF34	TMEM276	P0DTL5	446
ZNF34	MYC	P01106	436
ZNF34	COMMD5	Q9GZQ3	393
ZNF34	CCDC150	Q8NCX0	380
ZNF34	ZBTB21	Q9ULJ3	369
ZNF34	MAF1	Q9H063	353
ZNF34	CCDC30	Q5VVM6	352
ZNF34	LRRC24	Q50LG9	351
ZNF34	TTK	P33981	350
ZNF34	KAT14	Q9H8E8	349
ZNF34	PHF8	Q9UPP1	346

IntAct

16 interactions, top by confidence:

A	B	Type	Score
ZNF34	VAC14	psi-mi:“MI:0915”(physical association)	0.670
VAC14	ZNF34	psi-mi:“MI:0915”(physical association)	0.670
KRTAP10-5	ZNF34	psi-mi:“MI:0915”(physical association)	0.560
TRIM28	ZNF316	psi-mi:“MI:0914”(association)	0.530
TRIM28	ZNF320	psi-mi:“MI:0914”(association)	0.530
PB2		psi-mi:“MI:0914”(association)	0.350
ZNF34	IPO8	psi-mi:“MI:0914”(association)	0.350
ZNF34	LRP4	psi-mi:“MI:0914”(association)	0.350
FMR1	ZNF34	psi-mi:“MI:0915”(physical association)	0.000
RSPH1	ZNF34	psi-mi:“MI:0915”(physical association)	0.000
TIAM1	ZNF34	psi-mi:“MI:0915”(physical association)	0.000

BioGRID (53): ZNF34 (Two-hybrid), ZNF34 (Two-hybrid), ZNF34 (Two-hybrid), KRTAP10-5 (Two-hybrid), ZNF34 (Affinity Capture-MS), ZNF34 (Two-hybrid), ZNF34 (Two-hybrid), ZNF34 (Two-hybrid), ZNF34 (Two-hybrid), ZNF34 (Two-hybrid), ZNF34 (Two-hybrid), ZNF34 (Two-hybrid), ZNF34 (Two-hybrid), ZNF34 (Two-hybrid), ZNF34 (Two-hybrid)

ESM2 similar proteins: A0A087WUV0, A0JNB1, A2VDP4, B2RUI1, P0CG31, P10072, P17025, P17036, P17097, P18733, P51814, Q08ER8, Q09FC8, Q0VGE8, Q14590, Q15937, Q16600, Q2M3X9, Q4V8A8, Q5CZA5, Q5R8G9, Q5RBX0, Q5VIY5, Q68DI1, Q6J6I6, Q6NX49, Q6P1L6, Q6PG37, Q6ZMS4, Q6ZMW2, Q80YP6, Q86UD4, Q86Y25, Q8IZ26, Q8N184, Q8NB42, Q8NEK5, Q8TAF7, Q8TF47, Q8WXB4

Diamond homologs: A2A761, A2VDP4, A3KN32, A6QLU5, A6QPT6, A7MBI1, A8MT65, B4DU55, E9PYI1, O60765, O95780, P15622, P17014, P17032, P17098, P21506, P51508, P51814, P52736, P52738, P52742, Q02975, Q06730, Q06732, Q0VCB0, Q14587, Q16587, Q2KI58, Q2M3W8, Q3V080, Q49AA0, Q4R6C2, Q4V8A8, Q571J5, Q5HYK9, Q5JUW0, Q5JVG2, Q5MCW4, Q5MYW4, Q5R4K8

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

71 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	62
Likely benign	4
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

1004 predictions. Top by Δscore:

Variant	Effect	Δscore
8:144774602:AGAG:A	acceptor_gain	1.0000
8:144774603:GAG:G	acceptor_gain	1.0000
8:144774603:GAGC:G	acceptor_loss	1.0000
8:144774604:AGCT:A	acceptor_loss	1.0000
8:144774605:GCTGA:G	acceptor_loss	1.0000
8:144774606:C:CC	acceptor_gain	1.0000
8:144774606:CTGAA:C	acceptor_loss	1.0000
8:144777455:CA:C	donor_loss	1.0000
8:144777457:C:A	donor_loss	1.0000
8:144777575:CTC:C	acceptor_gain	1.0000
8:144777578:C:CC	acceptor_gain	1.0000
8:144777578:CTGGG:C	acceptor_loss	1.0000
8:144778032:CCTTA:C	donor_loss	1.0000
8:144778033:CTTA:C	donor_loss	1.0000
8:144778034:TTACC:T	donor_loss	1.0000
8:144778035:TACCC:T	donor_loss	1.0000
8:144778036:A:AC	donor_gain	1.0000
8:144778036:AC:A	donor_gain	1.0000
8:144778037:C:A	donor_loss	1.0000
8:144778037:C:CC	donor_gain	1.0000
8:144778037:CC:C	donor_gain	1.0000
8:144778037:CCCA:C	donor_gain	1.0000
8:144780281:C:CC	acceptor_gain	1.0000
8:144774601:AAGAG:A	acceptor_gain	0.9900
8:144774604:AG:A	acceptor_gain	0.9900
8:144777573:TACTC:T	acceptor_gain	0.9900
8:144778036:ACC:A	donor_gain	0.9900
8:144778037:CCC:C	donor_gain	0.9900
8:144778037:CCCAG:C	donor_gain	0.9900
8:144778077:C:A	donor_gain	0.9900

AlphaMissense

3590 scored. Top likely-pathogenic:

Variant	Protein change	am_pathogenicity
8:144773665:G:C	F428L	0.999
8:144773665:G:T	F428L	0.999
8:144773667:A:G	F428L	0.999
8:144773749:A:C	F400L	0.999
8:144773749:A:T	F400L	0.999
8:144773751:A:G	F400L	0.999
8:144773801:C:G	R383P	0.999
8:144773833:G:C	F372L	0.999
8:144773833:G:T	F372L	0.999
8:144773835:A:G	F372L	0.999
8:144773413:G:C	F512L	0.998
8:144773413:G:T	F512L	0.998
8:144773415:A:G	F512L	0.998
8:144773497:G:C	F484L	0.998
8:144773497:G:T	F484L	0.998
8:144773499:A:G	F484L	0.998
8:144773581:G:C	F456L	0.998
8:144773581:G:T	F456L	0.998
8:144773583:A:G	F456L	0.998
8:144773750:A:G	F400S	0.998
8:144773900:A:G	L350P	0.998
8:144773917:A:C	F344L	0.998
8:144773917:A:T	F344L	0.998
8:144773919:A:G	F344L	0.998
8:144774001:G:C	F316L	0.998
8:144774001:G:T	F316L	0.998
8:144774003:A:G	F316L	0.998
8:144773329:G:C	F540L	0.997
8:144773329:G:T	F540L	0.997
8:144773331:A:G	F540L	0.997

dbSNP variants (sampled 300 via entrez): RS1000245254 (8:144773198 G>A,C), RS1000484896 (8:144787528 G>A), RS1000587579 (8:144783106 C>A,T), RS1000747224 (8:144781088 T>C), RS1000769741 (8:144777896 C>G,T), RS1000807965 (8:144781386 A>C), RS1000847271 (8:144771799 T>C), RS1001178211 (8:144781258 T>C), RS1001260740 (8:144785532 C>T), RS1001304599 (8:144780344 T>G), RS1001328183 (8:144776509 A>C), RS1001441281 (8:144780669 A>G), RS1001649620 (8:144781584 C>T), RS1001692038 (8:144785341 G>A), RS1002045216 (8:144786550 C>T)

Disease associations

OMIM: gene MIM:194526 | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

6 associations (top):

Study	Trait	p-value
GCST006867_73	Type 2 diabetes	2.000000e-08
GCST006879_12	Blood metabolite levels	4.000000e-10
GCST006879_13	Blood metabolite levels	2.000000e-09
GCST006879_14	Blood metabolite levels	2.000000e-11
GCST006879_5	Blood metabolite levels	2.000000e-12
GCST007005_4	Logical memory (immediate recall) in normal cognition	2.000000e-07

EFO canonical traits (1, from GWAS)

EFO ID	Trait name
EFO:0004874	memory performance

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

23 total (human), top 23 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
sodium arsenite	affects expression, affects cotreatment, increases abundance, increases expression	2
Valproic Acid	decreases expression, increases methylation	2
FR900359	increases phosphorylation	1
tris(1,3-dichloro-2-propyl)phosphate	increases expression	1
manganese chloride	increases abundance, increases expression, affects cotreatment	1
cupric oxide	increases expression	1
abrine	increases expression	1
(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II)	decreases expression	1
Decitabine	affects expression	1
Leflunomide	increases expression	1
Arsenic	affects cotreatment, increases abundance, increases expression	1
Benzo(a)pyrene	affects methylation, decreases methylation	1
Cisplatin	affects expression	1
Copper	affects binding, decreases expression	1
Dieldrin	increases expression	1
Disulfiram	affects binding, decreases expression	1
Manganese	increases abundance, increases expression, affects cotreatment	1
Methyl Methanesulfonate	increases expression	1
Smoke	decreases expression	1
Tunicamycin	increases expression	1
Vanadates	increases expression	1
Cyclosporine	increases expression	1
Particulate Matter	decreases expression	1

Cellosaurus cell lines

1 cell lines: 1 transformed cell line

First 10 cell lines (id-ordered, not curated):

Cellosaurus	Name	Category	Sex
CVCL_XW34	HEK293 eGFP-ZNF34	Transformed cell line	Female

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.