ZNF346-IT1

Summary

ZNF346-IT1 (ZNF346 intronic transcript 1, HGNC:41423) is a long non-coding RNA gene on chromosome 5q35.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41423
Approved symbol	ZNF346-IT1
Name	ZNF346 intronic transcript 1
Location	5q35.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251666
Ensembl biotype	lncRNA
Entrez	106480741
RNAcentral	URS00003087EF — lncRNA, 745 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000515264

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000515264 — 2 exons

Exon	Start	End
ENSE00002037577	177051714	177051888
ENSE00002065534	177052394	177052963

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 77.72.

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.72	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.42	silver quality
ganglionic eminence	UBERON:0004023	68.06	gold quality
colonic epithelium	UBERON:0000397	67.55	silver quality
cortical plate	UBERON:0005343	67.29	gold quality
bone marrow cell	CL:0002092	67.00	silver quality
skeletal muscle tissue	UBERON:0001134	66.23	gold quality
superior frontal gyrus	UBERON:0002661	65.31	gold quality
ventricular zone	UBERON:0003053	64.99	gold quality
cerebellar cortex	UBERON:0002129	63.45	gold quality
cerebellum	UBERON:0002037	63.43	gold quality
tonsil	UBERON:0002372	63.31	gold quality
cerebellar hemisphere	UBERON:0002245	63.21	gold quality
right hemisphere of cerebellum	UBERON:0014890	63.15	gold quality
primary visual cortex	UBERON:0002436	63.05	gold quality
muscle tissue	UBERON:0002385	62.44	gold quality
urinary bladder	UBERON:0001255	61.72	gold quality
uterine cervix	UBERON:0000002	61.40	gold quality
descending thoracic aorta	UBERON:0002345	61.18	gold quality
adrenal tissue	UBERON:0018303	61.15	gold quality
endometrium	UBERON:0001295	61.14	gold quality
sural nerve	UBERON:0015488	61.03	silver quality
popliteal artery	UBERON:0002250	60.93	gold quality
tibial artery	UBERON:0007610	60.89	gold quality
myometrium	UBERON:0001296	60.80	gold quality
bone marrow	UBERON:0002371	60.71	gold quality
stromal cell of endometrium	CL:0002255	59.67	gold quality
cortex of kidney	UBERON:0001225	59.59	gold quality
right lobe of thyroid gland	UBERON:0001119	59.35	gold quality
prefrontal cortex	UBERON:0000451	58.98	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.37

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.