ZNF350-AS1

Summary

ZNF350-AS1 (ZNF350 antisense RNA 1, HGNC:48598) is a long non-coding RNA gene on chromosome 19q13.41.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48598
Approved symbol	ZNF350-AS1
Name	ZNF350 antisense RNA 1
Location	19q13.41
Locus type	RNA, long non-coding
Status	Approved
Aliases	uc002pyc
Ensembl gene	ENSG00000269235
Ensembl biotype	lncRNA
Entrez	101669766
RNAcentral	URS000075DEC7 — lncRNA, 726 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000595010, ENST00000600253, ENST00000658402, ENST00000661211, ENST00000692818, ENST00000797553, ENST00000797554, ENST00000797555, ENST00000797556, ENST00000797557, ENST00000797558, ENST00000797559, ENST00000797560

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000595010 — 3 exons

Exon	Start	End
ENSE00003118732	51976391	51976573
ENSE00004184355	51949112	51949235
ENSE00004184360	51980927	51981374

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 85.02.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4845 / max 71.7681, expressed in 150 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
177280	0.3523	134
177281	0.1243	51
177282	0.0080	3

Top tissues by expression

136 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	85.02	gold quality
testis	UBERON:0000473	84.19	gold quality
right testis	UBERON:0004534	83.91	gold quality
nucleus accumbens	UBERON:0001882	82.26	gold quality
cortical plate	UBERON:0005343	80.88	gold quality
caudate nucleus	UBERON:0001873	80.17	gold quality
placenta	UBERON:0001987	79.61	gold quality
putamen	UBERON:0001874	79.36	gold quality
cerebellum	UBERON:0002037	78.93	gold quality
cerebellar cortex	UBERON:0002129	78.92	gold quality
cerebellar hemisphere	UBERON:0002245	78.86	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.62	gold quality
prostate gland	UBERON:0002367	78.62	gold quality
right hemisphere of cerebellum	UBERON:0014890	78.34	gold quality
left lobe of thyroid gland	UBERON:0001120	76.80	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.67	gold quality
thyroid gland	UBERON:0002046	76.40	gold quality
adult mammalian kidney	UBERON:0000082	75.76	gold quality
amygdala	UBERON:0001876	75.45	gold quality
ganglionic eminence	UBERON:0004023	75.44	gold quality
temporal lobe	UBERON:0001871	75.34	gold quality
right lobe of thyroid gland	UBERON:0001119	75.04	gold quality
brain	UBERON:0000955	74.93	gold quality
tibial artery	UBERON:0007610	74.70	gold quality
popliteal artery	UBERON:0002250	74.66	gold quality
Ammon’s horn	UBERON:0001954	74.45	gold quality
bone marrow	UBERON:0002371	74.41	gold quality
right uterine tube	UBERON:0001302	74.18	gold quality
hypothalamus	UBERON:0001898	74.00	gold quality
kidney	UBERON:0002113	73.58	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.72

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.