ZNF366

Summary

ZNF366 (zinc finger protein 366, HGNC:18316) is a protein-coding gene on chromosome 5q13.1, encoding Zinc finger protein 366 (Q8N895). Has transcriptional repression activity.

Enables nuclear estrogen receptor binding activity and transcription corepressor activity. Involved in negative regulation of intracellular estrogen receptor signaling pathway; negative regulation of transcription by RNA polymerase II; and response to estrogen. Located in nucleoplasm.

Source: NCBI Gene 167465 — RefSeq curated summary.

At a glance

• GWAS associations: 23
• Clinical variants (ClinVar): 145 total
• MANE Select transcript: NM_152625

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:18316
Approved symbol	ZNF366
Name	zinc finger protein 366
Location	5q13.1
Locus type	gene with protein product
Status	Approved
Aliases	FLJ39796
Ensembl gene	ENSG00000178175
Ensembl biotype	protein_coding
OMIM	610159
Entrez	167465

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 4 protein_coding, 1 protein_coding_CDS_not_defined

ENST00000318442, ENST00000414109, ENST00000514477, ENST00000867840, ENST00000964997

RefSeq mRNA: 1 — MANE Select: NM_152625 NM_152625

CCDS: CCDS4015

Canonical transcript exons

ENST00000318442 — 5 exons

Exon	Start	End
ENSE00001258349	72447243	72447417
ENSE00001258356	72456404	72456595
ENSE00001258377	72439903	72444291
ENSE00001258386	72460165	72461510
ENSE00002028089	72507251	72507410

Expression profiles

Bgee: expression breadth ubiquitous, 157 present calls, max score 76.26.

FANTOM5 (CAGE): breadth broad, TPM avg 2.3596 / max 165.5908, expressed in 371 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
62040	2.3248	369
203585	0.0348	9

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	76.26	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.58	gold quality
colonic epithelium	UBERON:0000397	73.42	gold quality
smooth muscle tissue	UBERON:0001135	73.06	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.93	gold quality
apex of heart	UBERON:0002098	71.98	gold quality
omental fat pad	UBERON:0010414	70.68	gold quality
peritoneum	UBERON:0002358	70.60	gold quality
vermiform appendix	UBERON:0001154	70.39	gold quality
heart left ventricle	UBERON:0002084	69.88	gold quality
adipose tissue of abdominal region	UBERON:0007808	69.09	gold quality
cardiac ventricle	UBERON:0002082	68.94	gold quality
lymph node	UBERON:0000029	68.05	gold quality
subcutaneous adipose tissue	UBERON:0002190	68.02	gold quality
muscle of leg	UBERON:0001383	67.88	gold quality
monocyte	CL:0000576	67.74	gold quality
leukocyte	CL:0000738	67.41	gold quality
gall bladder	UBERON:0002110	67.29	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.26	gold quality
gastrocnemius	UBERON:0001388	67.16	gold quality
body of uterus	UBERON:0009853	66.90	gold quality
heart	UBERON:0000948	66.62	gold quality
right atrium auricular region	UBERON:0006631	66.41	gold quality
upper lobe of left lung	UBERON:0008952	65.53	gold quality
cardiac atrium	UBERON:0002081	65.34	gold quality
right lung	UBERON:0002167	65.33	gold quality
right lobe of thyroid gland	UBERON:0001119	64.91	gold quality
calcaneal tendon	UBERON:0003701	64.75	gold quality
upper lobe of lung	UBERON:0008948	64.63	gold quality
caecum	UBERON:0001153	63.89	gold quality

Single-cell (SCXA)

Detected in 3 experiment(s), a significant marker in 3.

Experiment	Marker?	Max mean expression
E-MTAB-9801	yes	8.36
E-MTAB-6678	yes	7.54
E-ANND-3	yes	4.59

Regulation

Is transcription factor: no

miRNA regulators (miRDB)

135 targeting ZNF366, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNA	Max score	Avg score	miRNA target_count
HSA-MIR-5011-5P	100.00	83.46	5820
HSA-MIR-190A-3P	100.00	80.35	5520
HSA-MIR-29A-3P	100.00	73.11	1835
HSA-MIR-29B-3P	100.00	73.18	1833
HSA-MIR-29C-3P	100.00	73.15	1833
HSA-MIR-200B-3P	100.00	73.31	2693
HSA-MIR-200C-3P	100.00	73.35	2685
HSA-MIR-429	100.00	73.44	2698
HSA-MIR-4455	100.00	65.48	1587
HSA-MIR-186-5P	99.99	70.83	3707
HSA-MIR-6759-5P	99.99	66.54	785
HSA-MIR-513B-5P	99.99	69.96	2150
HSA-MIR-3688-3P	99.97	72.02	2834
HSA-MIR-6793-5P	99.97	65.95	758
HSA-MIR-3148	99.97	75.06	6478
HSA-MIR-7152-3P	99.97	67.47	849
HSA-MIR-1250-3P	99.96	70.04	4038
HSA-MIR-590-3P	99.96	74.34	6478
HSA-MIR-5688	99.96	73.23	4504
HSA-MIR-6778-3P	99.96	67.29	2693
HSA-MIR-495-3P	99.96	72.81	4197
HSA-MIR-551B-5P	99.96	71.28	3493
HSA-MIR-3912-5P	99.95	66.11	925
HSA-MIR-767-5P	99.95	70.85	993
HSA-MIR-6835-3P	99.93	70.49	2904
HSA-MIR-335-3P	99.93	73.36	4958
HSA-MIR-450B-5P	99.92	71.48	3175
HSA-MIR-498-3P	99.91	71.27	1114
HSA-MIR-1305	99.91	71.43	3443
HSA-MIR-8063	99.91	69.76	3146

Literature-anchored findings (GeneRIF, showing 10)

• DC-SCRIPT consists of a proline-rich region, 11 C2H2-type zinc fingers, and an acidic region. Localization studies reveal that DC-SCRIPT resides in the nucleus and that nuclear localization is critically dependent on the zinc fingers. (DC-SCRIPT) (PMID:16393996)
• Results indicate that ZNF366 may play an important role in regulating the expression of genes in response to estrogen. (PMID:17085477)
• Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study (PMID:19525478)
• DC-SCRIPT can act as a tumor suppressor in breast cancer development.[review] (PMID:20478364)
• study provides a higher level of evidence that DC-SCRIPT is indeed an independent, pure prognostic, factor for primary breast cancer and shows that DC-SCRIPT mRNA expression is most informative for either ESR1-positive and/or ESR2-low pT1 tumors (PMID:21122099)
• DC-SCRIPT is a key regulator of androgen receptor and vitamin d receptor that play an opposite role in prostate cancer etiology and loss of DC-SCRIPT may be involved in the onset of prostate cancer. (PMID:22473304)
• DC-SCRIPT has a primary role in the regulation of interleukin (IL)-10 production by monocytes. (PMID:22615205)
• DC-SCRIPT serves an important role in regulating GR function in DCs, corepressing GR-dependent upregulation of the tolerance-inducing transcription factor GILZ. (PMID:23440419)
• these data show that DC-SCRIPT acts as a novel regulator of CDKN2B and induces cell cycle arrest in ESR1-positive breast cancer cells. (PMID:25663546)
• These data demonstrate that besides nuclear receptor regulation, DC-SCRIPT also modulates activation of NF-kappaBp65 after TLR activation in human DCs. (PMID:26170389)

Cross-species orthologs

6 orthologs

Organism	Symbol	Gene ID
danio_rerio	znf366	ENSDARG00000040116
mus_musculus	Zfp366	ENSMUSG00000050919
rattus_norvegicus	Zfp366	ENSRNOG00000017249
drosophila_melanogaster	CG11902	FBGN0028647
drosophila_melanogaster	CG11696	FBGN0030314
drosophila_melanogaster	CG10631	FBGN0032817

Paralogs (7): ZNF671 (ENSG00000083814), ZNF710 (ENSG00000140548), ZNF212 (ENSG00000170260), ZNF662 (ENSG00000182983), ZNF667 (ENSG00000198046), ZNF783 (ENSG00000204946), ZNF865 (ENSG00000261221)

Protein

Protein identifiers

Zinc finger protein 366 — Q8N895 (reviewed: Q8N895)

Alternative names: Dendritic cell-specific transcript protein

All UniProt accessions (2): Q8N895, F8W732

UniProt curated annotations — full annotation on UniProt →

Function. Has transcriptional repression activity. Acts as a corepressor of ESR1; the function seems to involve CTBP1 and histone deacetylases.

Subunit / interactions. Interacts with ESR1 and NRIP1. Interacts (via PXDLS motif) with CTBP1.

Subcellular location. Nucleus.

Tissue specificity. Expressed in immature and mature dendritic cells (DCs). Not detected in other blood cell types.

RefSeq proteins (1): NP_689838* (*=MANE)

Domains & families (InterPro)

ID	Name	Type
IPR013087	Znf_C2H2_type	Domain
IPR036236	Znf_C2H2_sf	Homologous_superfamily
IPR050636	C2H2-ZF_domain-containing	Family

Pfam: PF00096, PF13912

UniProt features (25 total): zinc finger region 11, mutagenesis site 6, region of interest 4, chain 1, short sequence motif 1, compositionally biased region 1, sequence variant 1

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Model	pLDDT	Fraction very-high
AF-Q8N895-F1	57.54	0.15

Functional residue map

Curated UniProt residues grouped by drug-discovery relevance — catalytic, ligand-binding, modification, and mutation-validated positions. Source: UniProtKB sequence features.

Mutagenesis-validated functional residues (6):

Position	Phenotype
590	abolishes interaction with ctbp1 and in part relieves transcription repression; when associated with a-592.
592	abolishes interaction with ctbp1 and in part relieves transcription repression; when associated with a-590.
593	abolishes interaction with ctbp1. abolishes interaction with ctbp1; when associated with a-648.
645	decreases interaction with ctbp1; when associated with a-647.
647	decreases interaction with ctbp1; when associated with a-645.
648	no effect on interaction with ctbp1. abolishes interaction with ctbp1; when associated with a-593.

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 91 (showing top): GSE18804_BRAIN_VS_COLON_TUMORAL_MACROPHAGE_DN, GOBP_CELLULAR_RESPONSE_TO_LIPID, GOBP_NEGATIVE_REGULATION_OF_INTRACELLULAR_ESTROGEN_RECEPTOR_SIGNALING_PATHWAY, GOBP_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY, FOXO4_01, LHX3_01, FOXO1_01, GOBP_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION, GOBP_HORMONE_MEDIATED_SIGNALING_PATHWAY, CCANNAGRKGGC_UNKNOWN, GOBP_NEGATIVE_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY, GOBP_REGULATION_OF_INTRACELLULAR_ESTROGEN_RECEPTOR_SIGNALING_PATHWAY, GOBP_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS, GOBP_RESPONSE_TO_ESTROGEN, OCT1_06

GO Biological Process (3): negative regulation of transcription by RNA polymerase II (GO:0000122), negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147), response to estrogen (GO:0043627)

GO Molecular Function (8): RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978), DNA-binding transcription factor activity (GO:0003700), transcription corepressor activity (GO:0003714), zinc ion binding (GO:0008270), nuclear estrogen receptor binding (GO:0030331), DNA binding (GO:0003677), protein binding (GO:0005515), metal ion binding (GO:0046872)

GO Cellular Component (2): nucleus (GO:0005634), nucleoplasm (GO:0005654)

GO top-level categories

Rollup of top GO terms by namespace:

Category	Terms
negative regulation of DNA-templated transcription	2
regulation of transcription by RNA polymerase II	1
transcription by RNA polymerase II	1
estrogen receptor signaling pathway	1
negative regulation of intracellular steroid hormone receptor signaling pathway	1
regulation of intracellular estrogen receptor signaling pathway	1
response to hormone	1
RNA polymerase II transcription regulatory region sequence-specific DNA binding	1
cis-regulatory region sequence-specific DNA binding	1
transcription cis-regulatory region binding	1
regulation of DNA-templated transcription	1
transcription regulator activity	1
transcription coregulator activity	1
transition metal ion binding	1
nuclear receptor binding	1
nucleic acid binding	1
binding	1
cation binding	1
intracellular membrane-bounded organelle	1
nuclear lumen	1
cellular anatomical structure	1

Protein interactions and networks

STRING

806 interactions, top by confidence (×1000):

Protein A	Protein B	Partner UniProt	Score
ZNF366	CTBP1	Q13363	775
ZNF366	TMEM171	Q8WVE6	537
ZNF366	OR5M8	Q8NGP6	474
ZNF366	UBOX5	O94941	458
ZNF366	ZNF654	Q8IZM8	456
ZNF366	LZTS3	O60299	448
ZNF366	NRIP1	P48552	441
ZNF366	TMEM174	Q8WUU8	430
ZNF366	THNSL2	Q86YJ6	428
ZNF366	DDRGK1	Q96HY6	426
ZNF366	BTBD9	Q96Q07	426
ZNF366	DCLK3	Q9C098	415
ZNF366	TADA3	O75528	400
ZNF366	HLX	Q14774	393
ZNF366	SMYD1	Q8NB12	393

IntAct

127 interactions, top by confidence:

A	B	Type	Score
ZNF366	CEP70	psi-mi:“MI:0915”(physical association)	0.830
CEP70	ZNF366	psi-mi:“MI:0915”(physical association)	0.830
PSMA3	ZNF366	psi-mi:“MI:0915”(physical association)	0.740
ESR1	ZNF366	psi-mi:“MI:0915”(physical association)	0.630
ZNF366	ESR1	psi-mi:“MI:0915”(physical association)	0.630
ESR1	ZNF366	psi-mi:“MI:0407”(direct interaction)	0.630
CTBP1	ZNF366	psi-mi:“MI:0407”(direct interaction)	0.630
CTBP1	ZNF366	psi-mi:“MI:0915”(physical association)	0.630
ZNF366	CTBP1	psi-mi:“MI:0915”(physical association)	0.630
ZNF366	ESR1	psi-mi:“MI:0407”(direct interaction)	0.630
TARDBP	ZNF366	psi-mi:“MI:0915”(physical association)	0.610
ZNF366	CARD10	psi-mi:“MI:0915”(physical association)	0.560
ZNF366	AKAP8L	psi-mi:“MI:0915”(physical association)	0.560
ZNF366	A2M	psi-mi:“MI:0915”(physical association)	0.560
ZNF366	APBB2	psi-mi:“MI:0915”(physical association)	0.560

BioGRID (9): ZNF366 (Two-hybrid), ZNF366 (Two-hybrid), PSMA3 (Two-hybrid), ZNF366 (Two-hybrid), ZNF366 (Two-hybrid), ZNF366 (Two-hybrid), ZNF366 (Two-hybrid), KLHL15 (Affinity Capture-MS), UBE3A (Affinity Capture-MS)

ESM2 similar proteins: A0JPB4, A0PJY2, A1YPR0, A2A935, A4IFJ6, B0K011, B7ZRM8, B7ZRU9, O13089, O15090, O57415, O75626, P14404, P41182, P41183, P86413, Q03112, Q03267, Q05516, Q08DS3, Q0VDQ9, Q13422, Q15911, Q5XJQ7, Q60636, Q61329, Q62255, Q66JF8, Q6DBW0, Q6NS86, Q86UP3, Q86V15, Q8C208, Q8I7Z8, Q8K083, Q8N895, Q8TAX0, Q8VCZ7, Q8VDL9, Q90277

Diamond homologs: Q3U288, Q6NS86, Q8N1W2, Q8N895

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

145 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	131
Likely benign	4
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

1306 predictions. Top by Δscore:

Variant	Effect	Δscore
5:72447239:TTACC:T	donor_loss	1.0000
5:72447240:TACCT:T	donor_loss	1.0000
5:72447241:ACCTT:A	donor_loss	1.0000
5:72447242:CCTT:C	donor_loss	1.0000
5:72447413:CAAAG:C	acceptor_gain	1.0000
5:72447416:AG:A	acceptor_gain	1.0000
5:72447417:GC:G	acceptor_loss	1.0000
5:72447418:C:CA	acceptor_loss	1.0000
5:72444291:CCTG:C	acceptor_loss	0.9900
5:72444292:C:CC	acceptor_gain	0.9900
5:72444292:CTGCA:C	acceptor_loss	0.9900
5:72444293:T:C	acceptor_loss	0.9900
5:72447414:AAAG:A	acceptor_gain	0.9900
5:72447415:AAG:A	acceptor_gain	0.9900
5:72447418:C:CC	acceptor_gain	0.9900
5:72447421:T:C	acceptor_gain	0.9900
5:72447421:T:TC	acceptor_gain	0.9900
5:72448034:C:CT	acceptor_gain	0.9900
5:72448035:A:T	acceptor_gain	0.9900
5:72448038:C:CT	acceptor_gain	0.9900
5:72456399:CCCA:C	donor_loss	0.9900
5:72456400:CCA:C	donor_loss	0.9900
5:72456401:CAC:C	donor_loss	0.9900
5:72456402:A:C	donor_loss	0.9900
5:72456421:T:TA	donor_gain	0.9900
5:72456421:TC:T	donor_gain	0.9900
5:72456592:CACC:C	acceptor_gain	0.9900
5:72456594:CC:C	acceptor_gain	0.9900
5:72456595:CC:C	acceptor_gain	0.9900
5:72456595:CCTG:C	acceptor_loss	0.9900

AlphaMissense

4975 scored. Top likely-pathogenic:

Variant	Protein change	am_pathogenicity
5:72447289:G:C	H551Q	1.000
5:72447289:G:T	H551Q	1.000
5:72447291:G:C	H551D	1.000
5:72447299:A:G	L548P	1.000
5:72447301:G:C	N547K	1.000
5:72447301:G:T	N547K	1.000
5:72447305:C:T	G546E	1.000
5:72447306:C:G	G546R	1.000
5:72447306:C:T	G546R	1.000
5:72447311:A:G	L544P	1.000
5:72447316:G:C	F542L	1.000
5:72447316:G:T	F542L	1.000
5:72447317:A:G	F542S	1.000
5:72447318:A:G	F542L	1.000
5:72447328:G:C	C538W	1.000
5:72447330:A:G	C538R	1.000
5:72447337:G:C	C535W	1.000
5:72447339:A:G	C535R	1.000
5:72447343:G:C	F533L	1.000
5:72447343:G:T	F533L	1.000
5:72447345:A:G	F533L	1.000
5:72447361:G:C	H527Q	1.000
5:72447361:G:T	H527Q	1.000
5:72447363:G:C	H527D	1.000
5:72447365:A:G	L526P	1.000
5:72447373:G:C	H523Q	1.000
5:72447373:G:T	H523Q	1.000
5:72447374:T:C	H523R	1.000
5:72447375:G:C	H523D	1.000
5:72447375:G:T	H523N	1.000

dbSNP variants (sampled 300 via entrez): RS1000032618 (5:72502034 A>C,G), RS1000051475 (5:72459258 C>G), RS1000084919 (5:72466143 T>A), RS1000118851 (5:72503384 T>C), RS1000173744 (5:72462946 T>A), RS1000180850 (5:72504348 C>G), RS1000256759 (5:72465021 G>A), RS1000279346 (5:72492005 G>A), RS1000468800 (5:72442141 C>T), RS1000507729 (5:72461910 C>A,T), RS1000518171 (5:72457669 T>C), RS1000623866 (5:72461480 T>C), RS1000671216 (5:72508804 T>G), RS1000751351 (5:72490064 G>A), RS1000785411 (5:72509077 C>A,G,T)

Disease associations

OMIM: gene MIM:610159 | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

23 associations (top):

Study	Trait	p-value
GCST000101_10	Hip geometry	6.000000e-07
GCST003654_8	Bone mineral density (Ward’s triangle area)	2.000000e-06
GCST004625_13	Monocyte count	4.000000e-10
GCST005580_261	Intraocular pressure	2.000000e-10
GCST005580_84	Intraocular pressure	3.000000e-11
GCST006291_97	Spherical equivalent or myopia (age of diagnosis)	7.000000e-09
GCST006979_105	Heel bone mineral density	5.000000e-10
GCST007843_8	Rheumatoid arthritis	3.000000e-10
GCST007995_22	Asthma (childhood onset)	5.000000e-08
GCST008508_1	Stress sensitivity (neuroticism score x major depressive disorder status interaction)	3.000000e-06
GCST010002_30	Refractive error	1.000000e-12
GCST010243_1	Apolipoprotein B levels	4.000000e-15
GCST010245_109	LDL cholesterol levels	1.000000e-13
GCST90002389_205	Lymphocyte percentage of white cells	5.000000e-17
GCST90002389_206	Lymphocyte percentage of white cells	9.000000e-14
GCST90002393_151	Monocyte count	8.000000e-14
GCST90002393_152	Monocyte count	5.000000e-09
GCST90002398_468	Neutrophil count	1.000000e-24
GCST90002398_469	Neutrophil count	9.000000e-12
GCST90002399_393	Neutrophil percentage of white cells	2.000000e-21
GCST90002407_459	White blood cell count	4.000000e-28
GCST90013406_140	Liver enzyme levels (alkaline phosphatase)	3.000000e-14
GCST90020029_1263	Waist circumference adjusted for body mass index	6.000000e-09

EFO canonical traits (14, from GWAS)

EFO ID	Trait name
EFO:0004685	hip geometry
EFO:0007785	femoral neck bone mineral density
EFO:0005091	monocyte count
EFO:0004695	intraocular pressure measurement
EFO:0004847	age at onset
EFO:0009270	heel bone mineral density
EFO:0007660	neuroticism measurement
EFO:0004615	apolipoprotein B measurement
EFO:0004611	low density lipoprotein cholesterol measurement
EFO:0007993	lymphocyte percentage of leukocytes
EFO:0004833	neutrophil count
EFO:0007990	neutrophil percentage of leukocytes
EFO:0004533	alkaline phosphatase measurement
EFO:0007789	BMI-adjusted waist circumference

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

10 total (human), top 10 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
GW 1929	increases reaction, affects binding, increases activity	1
bisphenol S	increases methylation	1
Troglitazone	increases activity, increases reaction, affects binding	1
Arsenic	affects methylation	1
Benzo(a)pyrene	affects methylation	1
Estradiol	decreases reaction, increases activity	1
Progesterone	decreases reaction, increases activity	1
Promegestone	decreases reaction, increases activity	1
Tobacco Smoke Pollution	increases expression	1
Tretinoin	affects binding, increases activity, increases reaction	1

Cellosaurus cell lines

1 cell lines: 1 transformed cell line

First 10 cell lines (id-ordered, not curated):

Cellosaurus	Name	Category	Sex
CVCL_XW38	HEK293 eGFP-ZNF366	Transformed cell line	Female

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.