ZNF385D-AS1

Summary

ZNF385D-AS1 (ZNF385D antisense RNA 1, HGNC:41136) is a long non-coding RNA gene on chromosome 3p24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41136
Approved symbol	ZNF385D-AS1
Name	ZNF385D antisense RNA 1
Location	3p24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225542
Ensembl biotype	lncRNA
Entrez	100874216
RNAcentral	URS000075BDA9 — lncRNA, 732 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000412369, ENST00000662195

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412369 — 3 exons

Exon	Start	End
ENSE00001640687	21579628	21579959
ENSE00001748840	21542816	21542995
ENSE00001803786	21579189	21579381

Expression profiles

Bgee: expression breadth broad, 99 present calls, max score 93.25.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4216 / max 44.8696, expressed in 98 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
35684	0.1622	62
35685	0.1257	55
35683	0.0832	44
35686	0.0504	30

Top tissues by expression

99 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	93.25	gold quality
sural nerve	UBERON:0015488	86.70	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.37	gold quality
calcaneal tendon	UBERON:0003701	63.80	gold quality
colonic epithelium	UBERON:0000397	63.70	silver quality
skeletal muscle tissue	UBERON:0001134	63.52	gold quality
monocyte	CL:0000576	60.54	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.22	gold quality
adult mammalian kidney	UBERON:0000082	55.83	gold quality
prefrontal cortex	UBERON:0000451	54.35	gold quality
lymph node	UBERON:0000029	54.21	gold quality
blood	UBERON:0000178	53.81	gold quality
primary visual cortex	UBERON:0002436	53.66	gold quality
muscle of leg	UBERON:0001383	52.53	gold quality
bone marrow	UBERON:0002371	51.90	silver quality
endometrium	UBERON:0001295	51.74	silver quality
vermiform appendix	UBERON:0001154	51.73	gold quality
kidney	UBERON:0002113	51.58	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	51.28	gold quality
placenta	UBERON:0001987	50.76	gold quality
adrenal tissue	UBERON:0018303	50.76	silver quality
right uterine tube	UBERON:0001302	49.96	gold quality
urinary bladder	UBERON:0001255	48.95	silver quality
descending thoracic aorta	UBERON:0002345	48.75	gold quality
uterine cervix	UBERON:0000002	48.49	gold quality
thoracic mammary gland	UBERON:0005200	48.27	gold quality
islet of Langerhans	UBERON:0000006	48.09	gold quality
endocervix	UBERON:0000458	47.65	gold quality
stomach	UBERON:0000945	47.62	gold quality
cortex of kidney	UBERON:0001225	47.31	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.16

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.