ZNF426-DT

Summary

ZNF426-DT (ZNF426 divergent transcript, HGNC:53777) is a long non-coding RNA gene on chromosome 19p13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53777
Approved symbol	ZNF426-DT
Name	ZNF426 divergent transcript
Location	19p13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000278611
Ensembl biotype	lncRNA
Entrez	101928238
RNAcentral	URS0000A7741D — lncRNA, 937 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000613560, ENST00000619671, ENST00000653468, ENST00000702795, ENST00000805118

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000613560 — 2 exons

Exon	Start	End
ENSE00003749304	9538733	9538998
ENSE00003749337	9539406	9539734

Expression profiles

Bgee: expression breadth ubiquitous, 167 present calls, max score 90.54.

FANTOM5 (CAGE): breadth broad, TPM avg 1.2521 / max 22.1598, expressed in 686 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
173698	0.9307	538
173699	0.3214	168

Top tissues by expression

239 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	90.54	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	89.54	gold quality
buccal mucosa cell	CL:0002336	81.86	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.40	gold quality
nucleus accumbens	UBERON:0001882	79.56	gold quality
amygdala	UBERON:0001876	79.29	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	79.07	gold quality
hypothalamus	UBERON:0001898	78.51	gold quality
anterior cingulate cortex	UBERON:0009835	78.22	gold quality
putamen	UBERON:0001874	78.12	gold quality
spinal cord	UBERON:0002240	77.45	gold quality
substantia nigra	UBERON:0002038	77.04	gold quality
caudate nucleus	UBERON:0001873	76.75	gold quality
midbrain	UBERON:0001891	75.29	gold quality
right frontal lobe	UBERON:0002810	74.71	gold quality
oviduct epithelium	UBERON:0004804	74.27	gold quality
Brodmann (1909) area 9	UBERON:0013540	73.46	gold quality
prefrontal cortex	UBERON:0000451	72.58	gold quality
forebrain	UBERON:0001890	72.52	gold quality
colonic epithelium	UBERON:0000397	72.35	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	72.25	gold quality
neocortex	UBERON:0001950	71.93	gold quality
bone marrow cell	CL:0002092	71.92	silver quality
temporal lobe	UBERON:0001871	71.64	gold quality
Ammon’s horn	UBERON:0001954	71.64	gold quality
brain	UBERON:0000955	71.63	gold quality
adenohypophysis	UBERON:0002196	71.11	gold quality
frontal cortex	UBERON:0001870	71.03	gold quality
right testis	UBERON:0004534	70.87	gold quality
tendon of biceps brachii	UBERON:0008188	70.80	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.