ZNF436-AS1

Summary

ZNF436-AS1 (ZNF436 antisense RNA 1, HGNC:25122) is a long non-coding RNA gene on chromosome 1p36.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:25122
Approved symbol	ZNF436-AS1
Name	ZNF436 antisense RNA 1
Location	1p36.12
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ90508
Ensembl gene	ENSG00000249087
Ensembl biotype	lncRNA
Entrez	148898
RNAcentral	URS000075B7A5 — lncRNA, 704 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000335648, ENST00000437367, ENST00000454117, ENST00000458053, ENST00000518600, ENST00000518821, ENST00000671509, ENST00000689840, ENST00000690463, ENST00000703050, ENST00000703051, ENST00000724025, ENST00000724026, ENST00000724027, ENST00000724028, ENST00000724029

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000335648 — 1 exons

Exon	Start	End
ENSE00001333537	23369236	23371782

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 87.37.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 4.2781 / max 75.2944, expressed in 1399 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
1343	2.4435	962
1341	1.0484	566
1342	0.7861	374

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primary visual cortex	UBERON:0002436	87.37	gold quality
putamen	UBERON:0001874	87.06	gold quality
substantia nigra	UBERON:0002038	86.72	gold quality
nucleus accumbens	UBERON:0001882	86.61	gold quality
caudate nucleus	UBERON:0001873	86.29	gold quality
amygdala	UBERON:0001876	85.57	gold quality
right frontal lobe	UBERON:0002810	85.53	gold quality
temporal lobe	UBERON:0001871	85.38	gold quality
right hemisphere of cerebellum	UBERON:0014890	85.36	gold quality
right uterine tube	UBERON:0001302	85.34	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	85.25	gold quality
Ammon’s horn	UBERON:0001954	85.01	gold quality
Brodmann (1909) area 9	UBERON:0013540	84.96	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	84.81	gold quality
cerebellar hemisphere	UBERON:0002245	84.70	gold quality
anterior cingulate cortex	UBERON:0009835	84.67	gold quality
cerebellar cortex	UBERON:0002129	84.63	gold quality
cerebellum	UBERON:0002037	84.59	gold quality
superior frontal gyrus	UBERON:0002661	84.39	gold quality
brain	UBERON:0000955	84.38	gold quality
cerebral cortex	UBERON:0000956	84.21	gold quality
hypothalamus	UBERON:0001898	84.10	gold quality
left lobe of thyroid gland	UBERON:0001120	83.87	gold quality
thyroid gland	UBERON:0002046	83.69	gold quality
right lobe of thyroid gland	UBERON:0001119	83.65	gold quality
frontal cortex	UBERON:0001870	83.44	gold quality
prefrontal cortex	UBERON:0000451	82.11	gold quality
left testis	UBERON:0004533	81.98	gold quality
left ovary	UBERON:0002119	81.79	gold quality
right adrenal gland	UBERON:0001233	81.67	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.