ZNF454-DT

Summary

ZNF454-DT (ZNF454 divergent transcript, HGNC:55213) is a long non-coding RNA gene on chromosome 5q35.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55213
Approved symbol	ZNF454-DT
Name	ZNF454 divergent transcript
Location	5q35.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00009823
Ensembl gene	ENSG00000272431
Ensembl biotype	lncRNA
Entrez	118568820
RNAcentral	URS00026A204A — lncRNA, 2340 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000606195, ENST00000789536, ENST00000789538

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000606195 — 1 exons

Exon	Start	End
ENSE00003699431	178938677	178939223

Expression profiles

Bgee: expression breadth ubiquitous, 120 present calls, max score 86.50.

Top tissues by expression

120 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.50	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.87	silver quality
ventricular zone	UBERON:0003053	66.48	gold quality
ganglionic eminence	UBERON:0004023	64.64	gold quality
lymph node	UBERON:0000029	62.00	gold quality
apex of heart	UBERON:0002098	59.53	gold quality
cerebellar hemisphere	UBERON:0002245	57.73	gold quality
cerebellar cortex	UBERON:0002129	57.65	gold quality
cerebellum	UBERON:0002037	57.63	gold quality
primary visual cortex	UBERON:0002436	56.92	gold quality
right coronary artery	UBERON:0001625	56.91	gold quality
body of uterus	UBERON:0009853	56.61	gold quality
right hemisphere of cerebellum	UBERON:0014890	56.53	gold quality
ovary	UBERON:0000992	56.09	gold quality
pituitary gland	UBERON:0000007	55.92	gold quality
left ovary	UBERON:0002119	55.92	gold quality
monocyte	CL:0000576	55.58	gold quality
right ovary	UBERON:0002118	55.31	gold quality
myometrium	UBERON:0001296	54.86	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	54.79	gold quality
substantia nigra	UBERON:0002038	54.58	gold quality
metanephros cortex	UBERON:0010533	54.33	gold quality
prefrontal cortex	UBERON:0000451	53.80	gold quality
islet of Langerhans	UBERON:0000006	53.79	gold quality
vermiform appendix	UBERON:0001154	53.52	gold quality
prostate gland	UBERON:0002367	53.46	gold quality
mucosa of transverse colon	UBERON:0004991	53.45	gold quality
descending thoracic aorta	UBERON:0002345	53.12	gold quality
brain	UBERON:0000955	52.96	gold quality
adenohypophysis	UBERON:0002196	52.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.32

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.