ZNF460-AS1

Summary

ZNF460-AS1 (ZNF460 antisense RNA 1, HGNC:53774) is a long non-coding RNA gene on chromosome 19q13.43.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53774
Approved symbol	ZNF460-AS1
Name	ZNF460 antisense RNA 1
Location	19q13.43
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267871
Ensembl biotype	lncRNA
Entrez	105372476
RNAcentral	URS0000A773C1 — lncRNA, 782 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000597601, ENST00000601567, ENST00000669944, ENST00000671172, ENST00000804658, ENST00000804659, ENST00000804660, ENST00000804661, ENST00000804662, ENST00000804663, ENST00000804664, ENST00000804665

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000597601 — 3 exons

Exon	Start	End
ENSE00003003388	57276935	57277056
ENSE00004196157	57267188	57267712
ENSE00004196167	57280279	57280412

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 95.34.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0565 / max 10.3419, expressed in 25 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
208948	0.0565	25

Top tissues by expression

136 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
thymus	UBERON:0002370	95.34	gold quality
cerebellar vermis	UBERON:0004720	86.19	gold quality
quadriceps femoris	UBERON:0001377	82.28	gold quality
right uterine tube	UBERON:0001302	76.07	gold quality
gastrocnemius	UBERON:0001388	76.02	gold quality
muscle of leg	UBERON:0001383	75.55	gold quality
right lobe of thyroid gland	UBERON:0001119	73.72	gold quality
nucleus accumbens	UBERON:0001882	73.66	gold quality
thyroid gland	UBERON:0002046	73.53	gold quality
left lobe of thyroid gland	UBERON:0001120	73.39	gold quality
pituitary gland	UBERON:0000007	73.11	gold quality
putamen	UBERON:0001874	72.66	gold quality
adenohypophysis	UBERON:0002196	72.64	gold quality
caudate nucleus	UBERON:0001873	72.36	gold quality
lower esophagus muscularis layer	UBERON:0035833	71.93	gold quality
prostate gland	UBERON:0002367	71.92	gold quality
substantia nigra	UBERON:0002038	71.89	gold quality
lower esophagus	UBERON:0013473	71.89	gold quality
popliteal artery	UBERON:0002250	71.87	gold quality
tibial artery	UBERON:0007610	71.85	gold quality
muscle layer of sigmoid colon	UBERON:0035805	71.83	gold quality
hindlimb stylopod muscle	UBERON:0004252	71.82	gold quality
apex of heart	UBERON:0002098	71.76	gold quality
skeletal muscle tissue	UBERON:0001134	71.61	gold quality
amygdala	UBERON:0001876	71.53	gold quality
Ammon’s horn	UBERON:0001954	71.42	gold quality
temporal lobe	UBERON:0001871	71.40	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	71.35	gold quality
islet of Langerhans	UBERON:0000006	71.20	gold quality
anterior cingulate cortex	UBERON:0009835	71.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.69

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.