ZNF474-AS1

Summary

ZNF474-AS1 (ZNF474 antisense RNA 1, HGNC:41019) is a long non-coding RNA gene on chromosome 5q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41019
Approved symbol	ZNF474-AS1
Name	ZNF474 antisense RNA 1
Location	5q23.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249610
Ensembl biotype	lncRNA
Entrez	107986445
RNAcentral	URS00001BD2F9 — lncRNA, 428 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000505209

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000505209 — 2 exons

Exon	Start	End
ENSE00002032482	122155933	122156015
ENSE00002061245	122154496	122154840

Expression profiles

Bgee: expression breadth ubiquitous, 102 present calls, max score 88.86.

Top tissues by expression

102 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.86	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	87.18	gold quality
right uterine tube	UBERON:0001302	86.35	gold quality
ventricular zone	UBERON:0003053	75.17	gold quality
cortical plate	UBERON:0005343	73.29	gold quality
calcaneal tendon	UBERON:0003701	70.49	gold quality
fallopian tube	UBERON:0003889	69.94	gold quality
stromal cell of endometrium	CL:0002255	64.22	gold quality
monocyte	CL:0000576	58.75	gold quality
endometrium	UBERON:0001295	58.51	gold quality
gall bladder	UBERON:0002110	58.13	gold quality
corpus callosum	UBERON:0002336	56.87	gold quality
islet of Langerhans	UBERON:0000006	56.69	gold quality
endocervix	UBERON:0000458	56.57	gold quality
prefrontal cortex	UBERON:0000451	55.98	gold quality
blood	UBERON:0000178	55.71	gold quality
muscle of leg	UBERON:0001383	55.23	gold quality
right lung	UBERON:0002167	55.20	gold quality
left testis	UBERON:0004533	54.88	gold quality
testis	UBERON:0000473	54.79	gold quality
right testis	UBERON:0004534	54.51	gold quality
lung	UBERON:0002048	53.95	gold quality
smooth muscle tissue	UBERON:0001135	53.62	gold quality
amygdala	UBERON:0001876	53.09	gold quality
hypothalamus	UBERON:0001898	52.85	gold quality
right lobe of thyroid gland	UBERON:0001119	52.49	gold quality
liver	UBERON:0002107	52.20	gold quality
lower esophagus muscularis layer	UBERON:0035833	51.99	gold quality
heart left ventricle	UBERON:0002084	51.72	gold quality
gastrocnemius	UBERON:0001388	51.64	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.