ZNF497-AS1

Summary

ZNF497-AS1 (ZNF497 antisense RNA 1, HGNC:55277) is a long non-coding RNA gene on chromosome 19q13.43.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55277
Approved symbol	ZNF497-AS1
Name	ZNF497 antisense RNA 1
Location	19q13.43
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000269054
Ensembl biotype	lncRNA
Entrez	105372483
RNAcentral	URS0000A76E2F — lncRNA, 736 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000599889, ENST00000663335

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000599889 — 3 exons

Exon	Start	End
ENSE00002988986	58364536	58364599
ENSE00003064707	58366034	58367620
ENSE00003121182	58362569	58362752

Expression profiles

Bgee: expression breadth ubiquitous, 151 present calls, max score 83.44.

Top tissues by expression

237 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	83.44	gold quality
left ovary	UBERON:0002119	70.06	gold quality
right lobe of thyroid gland	UBERON:0001119	68.65	gold quality
right ovary	UBERON:0002118	68.54	gold quality
left lobe of thyroid gland	UBERON:0001120	67.95	gold quality
thyroid gland	UBERON:0002046	66.98	gold quality
body of uterus	UBERON:0009853	66.61	gold quality
adenohypophysis	UBERON:0002196	65.71	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	65.19	gold quality
ventricular zone	UBERON:0003053	65.10	gold quality
left uterine tube	UBERON:0001303	64.88	gold quality
ovary	UBERON:0000992	64.81	gold quality
endocervix	UBERON:0000458	64.34	gold quality
pituitary gland	UBERON:0000007	64.16	gold quality
metanephros cortex	UBERON:0010533	63.36	gold quality
ectocervix	UBERON:0012249	62.63	gold quality
ganglionic eminence	UBERON:0004023	61.50	gold quality
apex of heart	UBERON:0002098	61.27	gold quality
cortical plate	UBERON:0005343	60.98	gold quality
muscle layer of sigmoid colon	UBERON:0035805	60.96	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	60.73	gold quality
lower esophagus muscularis layer	UBERON:0035833	60.71	gold quality
lower esophagus	UBERON:0013473	60.66	gold quality
tibial nerve	UBERON:0001323	60.63	gold quality
left adrenal gland cortex	UBERON:0035825	60.46	gold quality
left adrenal gland	UBERON:0001234	60.38	gold quality
uterine cervix	UBERON:0000002	60.14	gold quality
stromal cell of endometrium	CL:0002255	59.89	gold quality
cortex of kidney	UBERON:0001225	59.61	gold quality
body of pancreas	UBERON:0001150	59.57	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.85

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.