ZNF497-AS2

Summary

ZNF497-AS2 (ZNF497 antisense RNA 2, HGNC:58325) is a long non-coding RNA gene on chromosome 19q13.43.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58325
Approved symbol	ZNF497-AS2
Name	ZNF497 antisense RNA 2
Location	19q13.43
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000268049
Ensembl biotype	lncRNA
Entrez	139440228
RNAcentral	URS00002DBEEC — lncRNA, 1154 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000599952

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000599952 — 2 exons

Exon	Start	End
ENSE00003071870	58357999	58358238
ENSE00003166145	58358690	58359603

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 86.54.

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.54	gold quality
right uterine tube	UBERON:0001302	74.05	gold quality
cerebellum	UBERON:0002037	73.46	gold quality
cerebellar cortex	UBERON:0002129	73.36	gold quality
cerebellar hemisphere	UBERON:0002245	73.29	gold quality
right hemisphere of cerebellum	UBERON:0014890	72.86	gold quality
stromal cell of endometrium	CL:0002255	71.64	gold quality
cortical plate	UBERON:0005343	70.22	gold quality
pituitary gland	UBERON:0000007	69.89	gold quality
adenohypophysis	UBERON:0002196	69.11	gold quality
prefrontal cortex	UBERON:0000451	68.08	gold quality
frontal cortex	UBERON:0001870	67.70	gold quality
superior frontal gyrus	UBERON:0002661	67.51	gold quality
nucleus accumbens	UBERON:0001882	67.32	gold quality
right frontal lobe	UBERON:0002810	66.98	gold quality
brain	UBERON:0000955	66.69	gold quality
primary visual cortex	UBERON:0002436	66.55	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	66.48	gold quality
cerebral cortex	UBERON:0000956	66.10	gold quality
fallopian tube	UBERON:0003889	66.09	gold quality
Brodmann (1909) area 9	UBERON:0013540	66.01	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	65.84	gold quality
anterior cingulate cortex	UBERON:0009835	65.23	gold quality
islet of Langerhans	UBERON:0000006	64.78	gold quality
myometrium	UBERON:0001296	64.65	gold quality
caudate nucleus	UBERON:0001873	64.59	gold quality
left uterine tube	UBERON:0001303	64.28	gold quality
putamen	UBERON:0001874	64.28	gold quality
temporal lobe	UBERON:0001871	64.14	gold quality
granulocyte	CL:0000094	64.02	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.