ZNF503-AS2

Summary

ZNF503-AS2 (ZNF503 antisense RNA 2, HGNC:23525) is a long non-coding RNA gene on chromosome 10q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:23525
Approved symbol	ZNF503-AS2
Name	ZNF503 antisense RNA 2
Location	10q22.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237149
Ensembl biotype	lncRNA
Entrez	100131213
RNAcentral	URS000075AD5D — lncRNA, 2046 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 19 — 19 lncRNA

ENST00000425916, ENST00000466942, ENST00000484411, ENST00000486015, ENST00000491557, ENST00000527641, ENST00000725121, ENST00000725122, ENST00000725123, ENST00000725124, ENST00000725126, ENST00000725127, ENST00000725130, ENST00000725131, ENST00000725133, ENST00000725135, ENST00000725136, ENST00000725137, ENST00000725138

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425916 — 2 exons

Exon	Start	End
ENSE00001591406	75403054	75403351
ENSE00001759192	75407255	75408982

Expression profiles

Bgee: expression breadth ubiquitous, 197 present calls, max score 90.75.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3185 / max 21.3972, expressed in 93 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
105628	0.1199	51
105627	0.1031	40
105626	0.0954	55

Top tissues by expression

240 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cardiac muscle of right atrium	UBERON:0003379	90.75	gold quality
left ventricle myocardium	UBERON:0006566	89.68	gold quality
kidney epithelium	UBERON:0004819	89.13	silver quality
right adrenal gland	UBERON:0001233	84.17	gold quality
right adrenal gland cortex	UBERON:0035827	83.80	gold quality
nasal cavity epithelium	UBERON:0005384	83.39	gold quality
left adrenal gland cortex	UBERON:0035825	83.07	gold quality
adrenal cortex	UBERON:0001235	82.76	gold quality
left adrenal gland	UBERON:0001234	82.73	gold quality
myocardium	UBERON:0002349	82.53	gold quality
adrenal gland	UBERON:0002369	80.52	gold quality
nucleus accumbens	UBERON:0001882	79.20	gold quality
putamen	UBERON:0001874	78.91	gold quality
right uterine tube	UBERON:0001302	78.79	gold quality
epithelial cell of pancreas	CL:0000083	78.71	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	78.03	gold quality
adult mammalian kidney	UBERON:0000082	78.01	gold quality
lateral nuclear group of thalamus	UBERON:0002736	77.62	silver quality
lateral globus pallidus	UBERON:0002476	77.58	silver quality
caudate nucleus	UBERON:0001873	76.90	gold quality
vastus lateralis	UBERON:0001379	76.88	gold quality
secondary oocyte	CL:0000655	76.80	gold quality
vena cava	UBERON:0004087	76.62	silver quality
layer of synovial tissue	UBERON:0007616	76.46	silver quality
quadriceps femoris	UBERON:0001377	76.33	gold quality
right ovary	UBERON:0002118	76.32	gold quality
lower esophagus mucosa	UBERON:0035834	76.11	gold quality
left ovary	UBERON:0002119	75.94	gold quality
esophagus mucosa	UBERON:0002469	75.81	gold quality
cardia of stomach	UBERON:0001162	75.65	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.21

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.