ZNF516-AS1

Summary

ZNF516-AS1 (ZNF516 antisense RNA 1, HGNC:55324) is a long non-coding RNA gene on chromosome 18q23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55324
Approved symbol	ZNF516-AS1
Name	ZNF516 antisense RNA 1
Location	18q23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000265778
Ensembl biotype	lncRNA
Entrez	101927989
RNAcentral	URS000078837D — lncRNA, 1200 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000581996, ENST00000613453, ENST00000657360, ENST00000793027, ENST00000793028, ENST00000793029

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000581996 — 2 exons

Exon	Start	End
ENSE00002718762	76492757	76493920
ENSE00004175483	76491569	76491689

Expression profiles

Bgee: expression breadth ubiquitous, 135 present calls, max score 87.15.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 1.5370 / max 65.2104, expressed in 989 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
170793	1.1529	808
170795	0.2591	132
170794	0.1249	69

Top tissues by expression

138 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	87.15	gold quality
left testis	UBERON:0004533	85.29	gold quality
right testis	UBERON:0004534	85.15	gold quality
testis	UBERON:0000473	84.48	gold quality
pituitary gland	UBERON:0000007	81.81	gold quality
lower esophagus mucosa	UBERON:0035834	81.25	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.43	gold quality
adenohypophysis	UBERON:0002196	79.79	gold quality
right uterine tube	UBERON:0001302	77.24	gold quality
endometrium	UBERON:0001295	77.14	gold quality
esophagus mucosa	UBERON:0002469	77.14	gold quality
mucosa of transverse colon	UBERON:0004991	77.08	gold quality
fundus of stomach	UBERON:0001160	76.54	gold quality
bone marrow cell	CL:0002092	75.71	gold quality
fallopian tube	UBERON:0003889	75.19	gold quality
bone marrow	UBERON:0002371	74.97	gold quality
blood	UBERON:0000178	74.55	gold quality
urinary bladder	UBERON:0001255	74.35	gold quality
right lobe of liver	UBERON:0001114	74.25	gold quality
endocervix	UBERON:0000458	74.14	gold quality
monocyte	CL:0000576	74.01	gold quality
thymus	UBERON:0002370	73.94	silver quality
esophagus	UBERON:0001043	73.52	gold quality
uterine cervix	UBERON:0000002	73.43	gold quality
leukocyte	CL:0000738	73.39	gold quality
stromal cell of endometrium	CL:0002255	73.36	gold quality
body of stomach	UBERON:0001161	73.33	gold quality
myometrium	UBERON:0001296	72.87	gold quality
adrenal tissue	UBERON:0018303	72.76	gold quality
colonic epithelium	UBERON:0000397	72.66	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.37

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.