ZNF516-DT

Summary

ZNF516-DT (ZNF516 divergent transcript, HGNC:51248) is a long non-coding RNA gene on chromosome 18q23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51248
Approved symbol	ZNF516-DT
Name	ZNF516 divergent transcript
Location	18q23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000275763
Ensembl biotype	lncRNA
Entrez	400658
RNAcentral	URS0000EEAC8E — lncRNA, 2259 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000622985

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000622985 — 2 exons

Exon	Start	End
ENSE00003756455	76496279	76498088
ENSE00003757877	76495521	76495786

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 84.41.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 4.1242 / max 54.3425, expressed in 1335 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
170797	3.9687	1300
170798	0.1555	63

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.41	gold quality
islet of Langerhans	UBERON:0000006	64.76	gold quality
stromal cell of endometrium	CL:0002255	63.78	gold quality
right adrenal gland	UBERON:0001233	61.76	gold quality
left adrenal gland	UBERON:0001234	61.75	gold quality
right adrenal gland cortex	UBERON:0035827	61.50	gold quality
adrenal gland	UBERON:0002369	61.15	gold quality
left adrenal gland cortex	UBERON:0035825	60.99	gold quality
ventricular zone	UBERON:0003053	60.14	gold quality
ganglionic eminence	UBERON:0004023	59.03	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.70	silver quality
pancreas	UBERON:0001264	58.21	gold quality
leukocyte	CL:0000738	56.78	gold quality
monocyte	CL:0000576	56.54	gold quality
bone marrow	UBERON:0002371	56.51	gold quality
cortical plate	UBERON:0005343	56.43	silver quality
granulocyte	CL:0000094	55.79	gold quality
skeletal muscle tissue	UBERON:0001134	54.41	gold quality
blood	UBERON:0000178	53.96	silver quality
endometrium	UBERON:0001295	53.20	gold quality
adrenal tissue	UBERON:0018303	52.52	gold quality
putamen	UBERON:0001874	52.39	gold quality
prefrontal cortex	UBERON:0000451	51.38	gold quality
smooth muscle tissue	UBERON:0001135	50.92	gold quality
caudate nucleus	UBERON:0001873	50.57	gold quality
urinary bladder	UBERON:0001255	50.38	gold quality
liver	UBERON:0002107	50.30	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	50.26	gold quality
nucleus accumbens	UBERON:0001882	50.13	gold quality
duodenum	UBERON:0002114	50.04	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.