ZNF529-AS1

Summary

ZNF529-AS1 (ZNF529 antisense RNA 1, HGNC:51275) is a long non-coding RNA gene on chromosome 19q13.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51275
Approved symbol	ZNF529-AS1
Name	ZNF529 antisense RNA 1
Location	19q13.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233527
Ensembl biotype	lncRNA
Entrez	101927599
RNAcentral	URS00022AE7EC — lncRNA, 754 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 28 — 28 lncRNA

ENST00000448373, ENST00000475219, ENST00000494214, ENST00000592880, ENST00000670019, ENST00000670806, ENST00000687100, ENST00000729490, ENST00000729491, ENST00000729492, ENST00000729495, ENST00000729496, ENST00000729497, ENST00000729498, ENST00000729499, ENST00000729500, ENST00000729501, ENST00000729502, ENST00000729503, ENST00000729504, ENST00000729505, ENST00000729506, ENST00000729507, ENST00000729508, ENST00000729509, ENST00000729510, ENST00000729511, ENST00000729512

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000448373 — 3 exons

Exon	Start	End
ENSE00001602570	36573377	36573525
ENSE00001737325	36577141	36577915
ENSE00002748267	36574821	36574900

Expression profiles

Bgee: expression breadth ubiquitous, 184 present calls, max score 88.31.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 7.8492 / max 100.8505, expressed in 1750 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
175519	4.4249	1647
175520	3.2813	1442
175518	0.1430	62

Top tissues by expression

241 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	88.31	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.26	gold quality
adenohypophysis	UBERON:0002196	82.64	gold quality
cerebellar hemisphere	UBERON:0002245	81.41	gold quality
cerebellar cortex	UBERON:0002129	81.27	gold quality
right hemisphere of cerebellum	UBERON:0014890	81.17	gold quality
left lobe of thyroid gland	UBERON:0001120	80.92	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	80.23	gold quality
right lobe of thyroid gland	UBERON:0001119	80.16	gold quality
lower esophagus muscularis layer	UBERON:0035833	79.82	gold quality
anterior cingulate cortex	UBERON:0009835	79.81	gold quality
lower esophagus	UBERON:0013473	79.78	gold quality
thyroid gland	UBERON:0002046	79.75	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	79.39	gold quality
pituitary gland	UBERON:0000007	79.27	gold quality
apex of heart	UBERON:0002098	79.23	gold quality
left ovary	UBERON:0002119	79.17	gold quality
cerebellum	UBERON:0002037	79.16	gold quality
Brodmann (1909) area 9	UBERON:0013540	78.90	gold quality
nucleus accumbens	UBERON:0001882	78.83	gold quality
metanephros cortex	UBERON:0010533	78.83	gold quality
putamen	UBERON:0001874	78.81	gold quality
muscle layer of sigmoid colon	UBERON:0035805	78.76	gold quality
popliteal artery	UBERON:0002250	78.74	gold quality
tibial artery	UBERON:0007610	78.74	gold quality
caudate nucleus	UBERON:0001873	78.67	gold quality
right coronary artery	UBERON:0001625	78.54	gold quality
right lung	UBERON:0002167	78.46	gold quality
stromal cell of endometrium	CL:0002255	78.16	gold quality
mucosa of stomach	UBERON:0001199	78.08	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.38

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LincRNA ZNF529-AS1 inhibits hepatocellular carcinoma via FBXO31 and predicts the prognosis of hepatocellular carcinoma patients. (PMID:36803542)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.