ZNF560
gene geneOn this page
Also known as FLJ31986
Summary
ZNF560 (zinc finger protein 560, HGNC:26484) is a protein-coding gene on chromosome 19p13.2, encoding Zinc finger protein 560 (Q96MR9). May be involved in transcriptional regulation.
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus.
Source: NCBI Gene 147741 — RefSeq curated summary.
At a glance
- Clinical variants (ClinVar): 134 total
- MANE Select transcript:
NM_152476
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:26484 |
| Approved symbol | ZNF560 |
| Name | zinc finger protein 560 |
| Location | 19p13.2 |
| Locus type | gene with protein product |
| Status | Approved |
| Aliases | FLJ31986 |
| Ensembl gene | ENSG00000198028 |
| Ensembl biotype | protein_coding |
| Entrez | 147741 |
Gene structure
Transcript identifiers
Ensembl transcripts: 2 — 1 protein_coding, 1 retained_intron
ENST00000301480, ENST00000585974
RefSeq mRNA: 2 — MANE Select: NM_152476
NM_001351678, NM_152476
CCDS: CCDS12214
Canonical transcript exons
ENST00000301480 — 10 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001117061 | 9470392 | 9470518 |
| ENSE00001117063 | 9474199 | 9474325 |
| ENSE00001117068 | 9469630 | 9469710 |
| ENSE00001117071 | 9471296 | 9471378 |
| ENSE00001136484 | 9498128 | 9498215 |
| ENSE00001136490 | 9498538 | 9498616 |
| ENSE00001136502 | 9475284 | 9475369 |
| ENSE00001412956 | 9466355 | 9468334 |
| ENSE00001780373 | 9473179 | 9473259 |
| ENSE00003650186 | 9469105 | 9469187 |
Expression profiles
Bgee: expression breadth broad, 47 present calls, max score 83.14.
FANTOM5 (CAGE): breadth broad, TPM avg 0.6844 / max 51.5336, expressed in 241 samples.
FANTOM5 promoters (2 alternative TSS)
| Promoter ID | TPM avg | Samples expressed |
|---|---|---|
| 179006 | 0.5756 | 223 |
| 179005 | 0.1088 | 47 |
Top tissues by expression
192 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 83.14 | gold quality |
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 77.98 | gold quality |
| right testis | UBERON:0004534 | 75.37 | gold quality |
| left testis | UBERON:0004533 | 74.25 | gold quality |
| testis | UBERON:0000473 | 72.33 | gold quality |
| stromal cell of endometrium | CL:0002255 | 68.20 | gold quality |
| secondary oocyte | CL:0000655 | 61.19 | silver quality |
| cortical plate | UBERON:0005343 | 56.48 | gold quality |
| ventricular zone | UBERON:0003053 | 56.12 | gold quality |
| ganglionic eminence | UBERON:0004023 | 55.96 | gold quality |
| placenta | UBERON:0001987 | 45.91 | gold quality |
| oocyte | CL:0000023 | 43.93 | gold quality |
| lower esophagus mucosa | UBERON:0035834 | 43.55 | silver quality |
| skeletal muscle tissue of rectus abdominis | UBERON:0004511 | 43.37 | gold quality |
| granulocyte | CL:0000094 | 42.89 | silver quality |
| vastus lateralis | UBERON:0001379 | 41.41 | gold quality |
| quadriceps femoris | UBERON:0001377 | 41.37 | gold quality |
| superficial temporal artery | UBERON:0001614 | 41.33 | gold quality |
| palpebral conjunctiva | UBERON:0001812 | 41.10 | gold quality |
| mucosa of paranasal sinus | UBERON:0005030 | 40.98 | gold quality |
| amniotic fluid | UBERON:0000173 | 40.69 | gold quality |
| jejunal mucosa | UBERON:0000399 | 40.59 | gold quality |
| biceps brachii | UBERON:0001507 | 40.57 | gold quality |
| epithelium of nasopharynx | UBERON:0001951 | 40.45 | gold quality |
| myocardium | UBERON:0002349 | 40.45 | gold quality |
| gingival epithelium | UBERON:0001949 | 40.43 | gold quality |
| germinal epithelium of ovary | UBERON:0001304 | 40.33 | gold quality |
| esophagus squamous epithelium | UBERON:0006920 | 40.29 | gold quality |
| skeletal muscle tissue of biceps brachii | UBERON:0004502 | 40.27 | gold quality |
| jejunum | UBERON:0002115 | 40.18 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 1.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | yes | 4.08 |
Regulation
Is transcription factor: no
miRNA regulators (miRDB)
15 targeting ZNF560, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):
| miRNA | Max score | Avg score | miRNA target_count |
|---|---|---|---|
| HSA-MIR-3692-3P | 99.98 | 70.27 | 2139 |
| HSA-MIR-493-5P | 99.96 | 72.47 | 2382 |
| HSA-MIR-6508-5P | 99.92 | 70.67 | 2465 |
| HSA-MIR-4302 | 99.89 | 67.94 | 1187 |
| HSA-MIR-139-5P | 99.80 | 69.50 | 1399 |
| HSA-MIR-4255 | 99.72 | 67.70 | 1541 |
| HSA-MIR-3685 | 99.62 | 68.83 | 1621 |
| HSA-MIR-3120-3P | 99.54 | 70.28 | 2669 |
| HSA-MIR-3915 | 99.45 | 68.49 | 1905 |
| HSA-MIR-4666A-5P | 99.41 | 69.72 | 1887 |
| HSA-MIR-1253 | 99.12 | 67.08 | 1688 |
| HSA-MIR-519A-2-5P | 98.78 | 71.74 | 1401 |
| HSA-MIR-520B-5P | 98.78 | 71.74 | 1401 |
| HSA-MIR-4684-5P | 98.29 | 67.99 | 1650 |
| HSA-MIR-12116 | 97.94 | 68.91 | 595 |
Cross-species orthologs
5 orthologs
| Organism | Symbol | Gene ID |
|---|---|---|
| mus_musculus | Zfp78 | ENSMUSG00000055150 |
| rattus_norvegicus | ENSRNOG00000083797 | |
| drosophila_melanogaster | CG2712 | FBGN0024975 |
| drosophila_melanogaster | Phs | FBGN0036522 |
| drosophila_melanogaster | CG3281 | FBGN0260741 |
Paralogs (62): ZNF582 (ENSG00000018869), ZNF264 (ENSG00000083844), ZNF343 (ENSG00000088876), ZNF684 (ENSG00000117010), ZNF133 (ENSG00000125846), ZNF557 (ENSG00000130544), ZNF337 (ENSG00000130684), ZNF20 (ENSG00000132010), ZFP37 (ENSG00000136866), ZNF614 (ENSG00000142556), KRBOX4 (ENSG00000147121), ZNF599 (ENSG00000153896), ZNF19 (ENSG00000157429), ZNF589 (ENSG00000164048), PRDM9 (ENSG00000164256), ZNF180 (ENSG00000167384), ZNF558 (ENSG00000167785), ZNF35 (ENSG00000169981), ZNF778 (ENSG00000170100), ZNF439 (ENSG00000171291), ZNF440 (ENSG00000171295), ZNF556 (ENSG00000172000), ZNF554 (ENSG00000172006), ZNF596 (ENSG00000172748), ZNF80 (ENSG00000174255), ZNF266 (ENSG00000174652), ZNF25 (ENSG00000175395), ZNF77 (ENSG00000175691), ZNF169 (ENSG00000175787), ZNF404 (ENSG00000176222), ZNF491 (ENSG00000177599), ZNF620 (ENSG00000177842), ZNF619 (ENSG00000177873), ZNF875 (ENSG00000181666), ZNF329 (ENSG00000181894), ZFP90 (ENSG00000184939), ZNF566 (ENSG00000186017), ZNF529 (ENSG00000186020), ZNF749 (ENSG00000186230), ZNF555 (ENSG00000186300)
Protein
Protein identifiers
Zinc finger protein 560 — Q96MR9 (reviewed: Q96MR9)
All UniProt accessions (1): Q96MR9
UniProt curated annotations — full annotation on UniProt →
Function. May be involved in transcriptional regulation.
Subcellular location. Nucleus.
Similarity. Belongs to the krueppel C2H2-type zinc-finger protein family.
RefSeq proteins (2): NP_001338607, NP_689689* (*=MANE)
Domains & families (InterPro)
| ID | Name | Type |
|---|---|---|
| IPR001909 | KRAB | Domain |
| IPR013087 | Znf_C2H2_type | Domain |
| IPR036051 | KRAB_dom_sf | Homologous_superfamily |
| IPR036236 | Znf_C2H2_sf | Homologous_superfamily |
| IPR050589 | Ikaros_C2H2-ZF | Family |
Pfam: PF00096, PF01352, PF13912
UniProt features (21 total): zinc finger region 15, domain 2, sequence variant 2, chain 1, sequence conflict 1
Structure
Experimental structures (PDB)
0 structures.
Predicted structure (AlphaFold)
| Model | pLDDT | Fraction very-high |
|---|---|---|
| AF-Q96MR9-F1 | 64.24 | 0.00 |
Function
Pathways and Gene Ontology
Reactome pathways
1 pathways
| ID | Pathway |
|---|---|
| R-HSA-212436 | Generic Transcription Pathway |
MSigDB gene sets: 36 (showing top):
GARCIA_TARGETS_OF_FLI1_AND_DAX1_DN, chr19p13, GOMF_SEQUENCE_SPECIFIC_DNA_BINDING, FIGUEROA_AML_METHYLATION_CLUSTER_1_UP, FIGUEROA_AML_METHYLATION_CLUSTER_2_UP, FIGUEROA_AML_METHYLATION_CLUSTER_3_UP, FIGUEROA_AML_METHYLATION_CLUSTER_4_UP, FIGUEROA_AML_METHYLATION_CLUSTER_6_UP, FIGUEROA_AML_METHYLATION_CLUSTER_7_UP, GOBP_NEGATIVE_REGULATION_OF_TRANSCRIPTION_BY_RNA_POLYMERASE_II, GOBP_NEGATIVE_REGULATION_OF_NUCLEOBASE_CONTAINING_COMPOUND_METABOLIC_PROCESS, RATTENBACHER_BOUND_BY_CELF1, GOMF_TRANSCRIPTION_REGULATOR_ACTIVITY, MIR493_5P, GSE14308_TH1_VS_TH17_DN
GO Biological Process (3): negative regulation of transcription by RNA polymerase II (GO:0000122), regulation of transcription by RNA polymerase II (GO:0006357), regulation of DNA-templated transcription (GO:0006355)
GO Molecular Function (6): RNA polymerase II transcription regulatory region sequence-specific DNA binding (GO:0000977), DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981), zinc ion binding (GO:0008270), DNA binding (GO:0003677), sequence-specific DNA binding (GO:0043565), metal ion binding (GO:0046872)
GO Cellular Component (1): nucleus (GO:0005634)
Reactome top-level categories
Rollup of top-1 pathways:
| Category | Pathways |
|---|---|
| RNA Polymerase II Transcription | 1 |
GO top-level categories
Rollup of top GO terms by namespace:
| Category | Terms |
|---|---|
| regulation of transcription by RNA polymerase II | 2 |
| transcription by RNA polymerase II | 2 |
| negative regulation of DNA-templated transcription | 1 |
| regulation of DNA-templated transcription | 1 |
| DNA-templated transcription | 1 |
| regulation of gene expression | 1 |
| regulation of RNA biosynthetic process | 1 |
| transcription cis-regulatory region binding | 1 |
| chromatin | 1 |
| RNA polymerase II transcription regulatory region sequence-specific DNA binding | 1 |
| DNA-binding transcription factor activity | 1 |
| transition metal ion binding | 1 |
| nucleic acid binding | 1 |
| DNA binding | 1 |
| cation binding | 1 |
| intracellular membrane-bounded organelle | 1 |
Protein interactions and networks
STRING
310 interactions, top by confidence (×1000):
| Protein A | Protein B | Partner UniProt | Score |
|---|---|---|---|
| ZNF560 | HMX2 | A2RU54 | 380 |
| ZNF560 | LRRIQ3 | A6PVS8 | 349 |
| ZNF560 | DBNDD2 | Q9BQY9 | 348 |
| ZNF560 | NALF2 | O75949 | 323 |
| ZNF560 | SCML4 | Q8N228 | 318 |
| ZNF560 | C19orf33 | Q9GZP8 | 312 |
| ZNF560 | KRTAP8-1 | Q8IUC2 | 312 |
| ZNF560 | NRIP2 | Q9BQI9 | 310 |
| ZNF560 | CSAG1 | Q6PB30 | 305 |
| ZNF560 | CCNQ | Q8N1B3 | 305 |
| ZNF560 | TMEM130 | Q8N3G9 | 300 |
| ZNF560 | CYYR1 | Q96J86 | 297 |
| ZNF560 | SPESP1 | Q6UW49 | 296 |
| ZNF560 | TLCD4 | Q96MV1 | 293 |
| ZNF560 | GAS2L1 | Q99501 | 291 |
IntAct
0 interactions, top by confidence:
ESM2 similar proteins: A0JPL0, A6NK53, E7ETH6, E9Q8G5, O14628, P21506, P51508, Q09FC8, Q13360, Q2M218, Q2M3X9, Q2VY69, Q3KQV3, Q3SY52, Q4R882, Q5HY98, Q5REN4, Q5RES8, Q68DI1, Q6NX49, Q6P280, Q6PG37, Q6V9R5, Q6ZMW2, Q7Z340, Q86XU0, Q8IYI8, Q8N587, Q8N720, Q8N859, Q8NB42, Q8NDW4, Q8NEK5, Q8WXB4, Q96MR9, Q96MU6, Q96NG8, Q96NJ3, Q96SR6, Q9BR84
Diamond homologs: A0A1W2PQL4, A0JNB1, A0JPL0, A6NK53, A6QLU5, A6QPT6, A7MBI1, A8MT65, A8MUV8, A8MWA4, B2RXC5, B4DU55, B4DX44, E9PYI1, O14628, O75346, P0CH99, P0CI00, P17014, P17030, P17032, P17098, P51786, P85977, Q02386, Q06730, Q06732, Q0VAW7, Q12901, Q13360, Q14586, Q14588, Q14590, Q16587, Q2M3X9, Q2VY69, Q32M78, Q3ZCX4, Q49AA0, Q4R6J4
SIGNOR signaling
0 interactions.
Disease & clinical
Clinical variants and AI predictions
ClinVar
134 variants total. Per-class counts are floors (≥ shown; pagination cap):
| Classification | Count (floor) |
|---|---|
| Pathogenic | 0 |
| Likely pathogenic | 0 |
| Uncertain significance | 118 |
| Likely benign | 6 |
| Benign | 0 |
Top pathogenic / likely-pathogenic (0)
SpliceAI
1597 predictions. Top by Δscore:
| Variant | Effect | Δscore |
|---|---|---|
| 19:9468333:GC:G | acceptor_gain | 1.0000 |
| 19:9468334:CC:C | acceptor_gain | 1.0000 |
| 19:9468335:C:CA | acceptor_loss | 1.0000 |
| 19:9468335:C:CC | acceptor_gain | 1.0000 |
| 19:9468336:T:A | acceptor_loss | 1.0000 |
| 19:9468342:C:CT | acceptor_gain | 1.0000 |
| 19:9468344:C:CT | acceptor_gain | 1.0000 |
| 19:9468345:A:T | acceptor_gain | 1.0000 |
| 19:9469104:CCAA:C | donor_gain | 1.0000 |
| 19:9469142:T:C | donor_gain | 1.0000 |
| 19:9469626:TCA:T | donor_loss | 1.0000 |
| 19:9469627:CA:C | donor_loss | 1.0000 |
| 19:9469628:A:AC | donor_gain | 1.0000 |
| 19:9469628:A:AG | donor_loss | 1.0000 |
| 19:9469629:C:CC | donor_gain | 1.0000 |
| 19:9469629:C:CT | donor_loss | 1.0000 |
| 19:9469707:TAAC:T | acceptor_gain | 1.0000 |
| 19:9469708:AAC:A | acceptor_gain | 1.0000 |
| 19:9469709:AC:A | acceptor_gain | 1.0000 |
| 19:9469710:CC:C | acceptor_gain | 1.0000 |
| 19:9469711:C:CC | acceptor_gain | 1.0000 |
| 19:9469713:G:C | acceptor_gain | 1.0000 |
| 19:9469713:G:GC | acceptor_gain | 1.0000 |
| 19:9470387:CTTA:C | donor_loss | 1.0000 |
| 19:9470390:A:AC | donor_gain | 1.0000 |
| 19:9470390:A:T | donor_loss | 1.0000 |
| 19:9470390:AC:A | donor_gain | 1.0000 |
| 19:9470391:C:CG | donor_gain | 1.0000 |
| 19:9470391:CC:C | donor_gain | 1.0000 |
| 19:9470391:CCT:C | donor_gain | 1.0000 |
AlphaMissense
5237 scored. Top likely-pathogenic:
| Variant | Protein change | am_pathogenicity |
|---|---|---|
| 19:9467204:G:C | F581L | 0.994 |
| 19:9467204:G:T | F581L | 0.994 |
| 19:9467206:A:G | F581L | 0.994 |
| 19:9467708:A:C | F413L | 0.993 |
| 19:9467708:A:T | F413L | 0.993 |
| 19:9467710:A:G | F413L | 0.993 |
| 19:9467288:G:C | F553L | 0.987 |
| 19:9467288:G:T | F553L | 0.987 |
| 19:9467290:A:G | F553L | 0.987 |
| 19:9467792:G:C | F385L | 0.987 |
| 19:9467792:G:T | F385L | 0.987 |
| 19:9467794:A:G | F385L | 0.987 |
| 19:9467120:G:C | F609L | 0.983 |
| 19:9467120:G:T | F609L | 0.983 |
| 19:9467122:A:G | F609L | 0.983 |
| 19:9466616:A:C | F777L | 0.980 |
| 19:9466616:A:T | F777L | 0.980 |
| 19:9466618:A:G | F777L | 0.980 |
| 19:9467765:A:C | H394Q | 0.979 |
| 19:9467765:A:T | H394Q | 0.979 |
| 19:9467456:A:C | F497L | 0.978 |
| 19:9467456:A:T | F497L | 0.978 |
| 19:9467458:A:G | F497L | 0.978 |
| 19:9467681:A:C | H422Q | 0.978 |
| 19:9467681:A:T | H422Q | 0.978 |
| 19:9470483:G:C | F119L | 0.978 |
| 19:9470483:G:T | F119L | 0.978 |
| 19:9470485:A:G | F119L | 0.978 |
| 19:9467187:A:G | L587P | 0.977 |
| 19:9467429:A:C | H506Q | 0.977 |
dbSNP variants (sampled 300 via entrez): RS1000002683 (19:9469416 A>C), RS1000020831 (19:9456136 A>C), RS1000110503 (19:9475810 G>A), RS1000156887 (19:9497727 A>G), RS1000186586 (19:9496839 G>A), RS1000194164 (19:9457770 G>A,T), RS1000203338 (19:9463438 T>C,G), RS1000222117 (19:9479148 C>G,T), RS1000242385 (19:9490004 T>G), RS1000294627 (19:9490304 C>A), RS1000315752 (19:9459022 G>A), RS1000317637 (19:9463145 G>A), RS1000516620 (19:9480026 G>A), RS1000564375 (19:9459365 C>G), RS1000628734 (19:9491421 C>T)
Disease associations
OMIM: gene `` | disease phenotypes:
GenCC curated gene-disease
Mondo (1): prostate cancer (MONDO:0008315)
Orphanet (1): Familial prostate cancer (Orphanet:1331)
HPO phenotypes
0 total (0 of 0 shown, HPO-id order):
GWAS associations
0 associations (top):
MeSH disease descriptors (1)
| Descriptor | Name | Tree numbers |
|---|---|---|
| D011471 | Prostatic Neoplasms | C04.588.945.440.770; C12.100.500.260.750; C12.100.500.565.625; C12.200.294.260.750; C12.200.294.565.625; C12.200.758.409.750; C12.900.619.750 |
Drugs & pharmacology
Drug and pharmacology data
Is drug target: no
PharmGKB: 1 entry (VIP=true, CPIC=false)
CTD chemical–gene interactions
8 total (human), top 8 by PubMed support.
| Chemical | Actions (top 5) | PubMed papers |
|---|---|---|
| aristolochic acid I | increases expression | 1 |
| arsenite | decreases expression, increases methylation | 1 |
| bisphenol S | decreases methylation | 1 |
| Arsenic | affects methylation | 1 |
| Benzo(a)pyrene | affects methylation | 1 |
| Tobacco Smoke Pollution | increases expression | 1 |
| Tretinoin | increases expression | 1 |
| Aflatoxin B1 | increases methylation | 1 |
Cellosaurus cell lines
1 cell lines: 1 transformed cell line
First 10 cell lines (id-ordered, not curated):
| Cellosaurus | Name | Category | Sex |
|---|---|---|---|
| CVCL_XW64 | HEK293 eGFP-ZNF560 | Transformed cell line | Female |
Clinical trials (associated diseases)
300 trials via MONDO — disease-level, not drug-specific.
| Trial | Phase | Status | Title |
|---|---|---|---|
| NCT00029224 | PHASE4 | COMPLETED | Treatment With Zoledronic Acid in Patients With Breast Cancer, Multiple Myeloma, and Prostate Cancer With Cancer Related Bone Lesions |
| NCT00035997 | PHASE4 | COMPLETED | Open-label Trial on the Effect of I.V. Zoledronic Acid 4 mg on Bone Density in Hormone Sensitive Prostate Cancer Patients With Bone Metastasis |
| NCT00063609 | PHASE4 | COMPLETED | The Effect of Zoledronic Acid on Bone Loss in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy |
| NCT00103623 | PHASE4 | SUSPENDED | The Plenaxis® Experience Study |
| NCT00106392 | PHASE4 | COMPLETED | A Safety and Efficacy Study of Prograf in the Prevention of Erectile Dysfunction After Radical Prostatectomy |
| NCT00185029 | PHASE4 | UNKNOWN | MR-Lymphography and Lymph Node Staging in Prostate Cancer |
| NCT00199485 | PHASE4 | COMPLETED | Angelica Sinensis for the Treatment of Hot Flashes in Men Undergoing LHRH Therapy for Prostate Cancer |
| NCT00219219 | PHASE4 | COMPLETED | Zoledronic Acid in the Prevention of Skeletal-related Events in Hormone Refractory and Hormone-sensitive Prostate Cancer Patients With Bone Metastases |
| NCT00219271 | PHASE4 | COMPLETED | Effect Of Zoledronic Acid On Circulating And Bone Marrow-Residing Prostate Cancer Cells In Patients With Clinically Localized Prostate Cancer |
| NCT00237146 | PHASE4 | COMPLETED | Study to Evaluate Zoledronic Acid on Quality of Life and Skeletal-related Events as Adjuvant Treatment in Patients With Hormone-naïve Prostate Cancer and Bone Metastasis Who Have Undergone Orchiectomy |
| NCT00242554 | PHASE4 | COMPLETED | Open-label Phase IV Clinical Trial to Evaluate the Safety and Tolerability of Zoledronic Acid in Patients With Prostate Cancer and Bone Metastases |
| NCT00280098 | PHASE4 | COMPLETED | Docetaxel in the Treatment of Hormone Refractory Prostate Cancer |
| NCT00293696 | PHASE4 | COMPLETED | Casodex/Zoladex Biomarkers in Localised Prostate Cancer |
| NCT00334139 | PHASE4 | COMPLETED | Effect of Zoledronic Acid on Bone Metabolism in Patients With Bone Metastasis and Prostate or Breast Cancer |
| NCT00375765 | PHASE4 | COMPLETED | Effects On Dihydrotestosterone Regulated Gene Expression In Benign Prostatic Hyperplasia Or Prostate Cancer |
| NCT00391690 | PHASE4 | COMPLETED | Evaluation of Bone Markers as Diagnostic Tools for Early Detection of Bone Metastases in Patients With High Risk Prostate Cancer |
| NCT00422708 | PHASE4 | COMPLETED | Local Anesthesia for Prostate Biopsy |
| NCT00526331 | PHASE4 | COMPLETED | Evaluation of Arterial Pressure Based Cardiac Output for Goal-Directed Perioperative Therapy |
| NCT00590213 | PHASE4 | COMPLETED | Compare the Value of Prophylactic Versus Therapeutic Breast Radiotherapy in CASODEX |
| NCT00629330 | PHASE4 | TERMINATED | Dissemination of Prostate Cancer Screening to PCP’s in African American Communities |
| NCT00771966 | PHASE4 | COMPLETED | Radical Prostatectomy and Perioperative Fluid Therapy |
| NCT00805701 | PHASE4 | COMPLETED | Study Assessing The Efficacy And Safety Of Avodart (Dutasteride) At Improving Urinary Symptoms In Men With Prostate Cancer Who Are Undergoing Seed Implantation |
| NCT00859027 | PHASE4 | COMPLETED | Effect Of Risedronate On Bone Mass In Older Men Receiving Neoadjuvant Therapy For Prostate Cancer |
| NCT00906269 | PHASE4 | UNKNOWN | Can Hyperbaric Oxygen Improve Erectile Function Following Surgery for Prostate Cancer |
| NCT00953277 | PHASE4 | COMPLETED | Study of Nerve Reconstruction Using AVANCE in Subjects Who Undergo Robotic Assisted Prostatectomy for Treatment of Prostate Cancer |
| NCT00982800 | PHASE4 | COMPLETED | Does Postoperative Gabapentin Reduce Pain, Opioid Consumption and Anxiety and Have a Positive Effect on Health Related Quality of Life After Radical Prostatectomy? |
| NCT01083199 | PHASE4 | COMPLETED | Global Performance Evaluation of the AMS CONTINUUM™ Device |
| NCT01136226 | PHASE4 | COMPLETED | Evaluate Recovery of Testosterone for Patients Using Eligard |
| NCT01161563 | PHASE4 | COMPLETED | Randomized Crossover Trial to Assess the Tolerability of Gonadotropin Releasing Hormone (GnRH) Analogue Administration |
| NCT01230905 | PHASE4 | COMPLETED | Study to Monitor the Effects of Androgen Suppression Treatment on the Heart |
| NCT01296672 | PHASE4 | COMPLETED | 3 Month Finasteride Challenge Test Can Significantly Improve the Performance of Screening for Prostate Cancer |
| NCT01365143 | PHASE4 | TERMINATED | Prospective Randomized Trial Comparing Robotic Versus Open Radical Prostatectomy |
| NCT01379742 | PHASE4 | UNKNOWN | Comparison of Between ThinSeed™ and OncoSeed™ for Permanent Prostate Brachytherapy |
| NCT01486563 | PHASE4 | COMPLETED | Hydroxyethyl Starch and Renal Function After Radical Prostatectomy |
| NCT01511874 | PHASE4 | COMPLETED | Efficacy and Safety Study of ELIGARD 22.5mg With Prostate Cancer |
| NCT01512472 | PHASE4 | TERMINATED | Firmagon (Degarelix) Intermittent Therapy |
| NCT01547416 | PHASE4 | COMPLETED | The Effect of Combined General/Epidural Anesthesia Versus General Anesthesia on Diaphragmatic Function |
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