ZNF594-DT

Summary

ZNF594-DT (ZNF594 divergent transcript, HGNC:55347) is a long non-coding RNA gene on chromosome 17p13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55347
Approved symbol	ZNF594-DT
Name	ZNF594 divergent transcript
Location	17p13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261879
Ensembl biotype	lncRNA
Entrez	100130950
RNAcentral	URS0000CCE08B — lncRNA, 2172 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 21 — 21 lncRNA

ENST00000571689, ENST00000573772, ENST00000575601, ENST00000649359, ENST00000656594, ENST00000663434, ENST00000667038, ENST00000669386, ENST00000671211, ENST00000702138, ENST00000780146, ENST00000780147, ENST00000780148, ENST00000780149, ENST00000780150, ENST00000780151, ENST00000780152, ENST00000780153, ENST00000780154, ENST00000780155, ENST00000780156

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000571689 — 8 exons

Exon	Start	End
ENSE00002633803	5209750	5209895
ENSE00002649880	5214050	5214209
ENSE00002656228	5223317	5223484
ENSE00002672036	5192104	5192163
ENSE00002673927	5233824	5233942
ENSE00002678536	5234593	5234811
ENSE00002682637	5234948	5235643
ENSE00004151157	5215147	5215293

Expression profiles

Bgee: expression breadth ubiquitous, 160 present calls, max score 89.76.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 3.8902 / max 79.7076, expressed in 1334 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
159022	2.7563	1148
159020	0.6223	302
159021	0.5116	254

Top tissues by expression

244 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	89.76	gold quality
right hemisphere of cerebellum	UBERON:0014890	84.41	gold quality
cerebellar hemisphere	UBERON:0002245	84.29	gold quality
cerebellar cortex	UBERON:0002129	84.20	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.28	gold quality
adenohypophysis	UBERON:0002196	82.61	gold quality
left ovary	UBERON:0002119	81.86	gold quality
colonic epithelium	UBERON:0000397	81.71	gold quality
cerebellum	UBERON:0002037	81.43	gold quality
right lobe of thyroid gland	UBERON:0001119	81.31	gold quality
right ovary	UBERON:0002118	81.29	gold quality
left lobe of thyroid gland	UBERON:0001120	80.70	gold quality
pituitary gland	UBERON:0000007	79.61	gold quality
body of uterus	UBERON:0009853	79.35	gold quality
thyroid gland	UBERON:0002046	79.34	gold quality
apex of heart	UBERON:0002098	78.41	gold quality
endocervix	UBERON:0000458	78.26	gold quality
cortical plate	UBERON:0005343	77.95	gold quality
ventricular zone	UBERON:0003053	77.13	gold quality
metanephros cortex	UBERON:0010533	76.76	gold quality
right frontal lobe	UBERON:0002810	76.73	gold quality
stromal cell of endometrium	CL:0002255	76.72	gold quality
ectocervix	UBERON:0012249	76.40	gold quality
body of pancreas	UBERON:0001150	76.38	gold quality
Brodmann (1909) area 9	UBERON:0013540	76.05	gold quality
muscle layer of sigmoid colon	UBERON:0035805	75.89	gold quality
ganglionic eminence	UBERON:0004023	75.85	gold quality
left testis	UBERON:0004533	75.84	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	75.49	gold quality
left uterine tube	UBERON:0001303	75.46	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	7.48
E-ANND-3	yes	4.33

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.