ZNF649-AS1

Summary

ZNF649-AS1 (ZNF649 antisense RNA 1, HGNC:51285) is a long non-coding RNA gene on chromosome 19q13.41.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51285
Approved symbol	ZNF649-AS1
Name	ZNF649 antisense RNA 1
Location	19q13.41
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000268095
Ensembl biotype	lncRNA
Entrez	101928571
RNAcentral	URS000075D7B0 — lncRNA, 580 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000600329, ENST00000808742

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000600329 — 3 exons

Exon	Start	End
ENSE00003148775	51896161	51896296
ENSE00004203809	51900123	51900475
ENSE00004203811	51888023	51888126

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 92.90.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0818 / max 33.3803, expressed in 16 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
177278	0.0777	16
177277	0.0040	2

Top tissues by expression

229 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	92.90	gold quality
left testis	UBERON:0004533	90.63	gold quality
right testis	UBERON:0004534	90.59	gold quality
testis	UBERON:0000473	87.82	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.93	gold quality
adult organism	UBERON:0007023	75.64	gold quality
ganglionic eminence	UBERON:0004023	68.47	gold quality
sural nerve	UBERON:0015488	64.15	silver quality
epithelial cell of pancreas	CL:0000083	62.18	gold quality
medial globus pallidus	UBERON:0002477	62.08	gold quality
granulocyte	CL:0000094	60.46	gold quality
smooth muscle tissue	UBERON:0001135	57.50	gold quality
islet of Langerhans	UBERON:0000006	57.45	gold quality
globus pallidus	UBERON:0001875	57.45	gold quality
monocyte	CL:0000576	56.76	gold quality
tendon of biceps brachii	UBERON:0008188	56.51	gold quality
lower lobe of lung	UBERON:0008949	55.70	silver quality
vena cava	UBERON:0004087	55.27	gold quality
pancreatic ductal cell	CL:0002079	54.93	silver quality
cardiac muscle of right atrium	UBERON:0003379	54.85	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
calcaneal tendon	UBERON:0003701	53.88	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
prefrontal cortex	UBERON:0000451	52.80	gold quality
pancreas	UBERON:0001264	52.58	gold quality
vermiform appendix	UBERON:0001154	51.81	gold quality
tibialis anterior	UBERON:0001385	51.38	silver quality
lymph node	UBERON:0000029	51.34	gold quality
myocardium	UBERON:0002349	50.46	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.