ZNF655

Summary

ZNF655 (zinc finger protein 655, HGNC:30899) is a protein-coding gene on chromosome 7q22.1, encoding Zinc finger protein 655 (Q8N720). Probable transcription factor.

This gene encodes a zinc finger protein. The zinc finger proteins are involved in DNA binding and protein-protein interactions. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Source: NCBI Gene 79027 — RefSeq curated summary.

At a glance

• GWAS associations: 3
• Clinical variants (ClinVar): 86 total
• MANE Select transcript: NM_138494

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:30899
Approved symbol	ZNF655
Name	zinc finger protein 655
Location	7q22.1
Locus type	gene with protein product
Status	Approved
Aliases	VIK-1, VIK
Ensembl gene	ENSG00000197343
Ensembl biotype	protein_coding
OMIM	617891
Entrez	79027

Gene structure

Transcript identifiers

Ensembl transcripts: 32 — 22 protein_coding, 5 retained_intron, 4 nonsense_mediated_decay, 1 protein_coding_CDS_not_defined

ENST00000252713, ENST00000320583, ENST00000357864, ENST00000394163, ENST00000412636, ENST00000416144, ENST00000419215, ENST00000422164, ENST00000422422, ENST00000422647, ENST00000423973, ENST00000424881, ENST00000425063, ENST00000427931, ENST00000440391, ENST00000449244, ENST00000452314, ENST00000454654, ENST00000467680, ENST00000488751, ENST00000489320, ENST00000493277, ENST00000493947, ENST00000494357, ENST00000626122, ENST00000858641, ENST00000858642, ENST00000858643, ENST00000858644, ENST00000858645, ENST00000955592, ENST00000955593

RefSeq mRNA: 11 — MANE Select: NM_138494 NM_001009958, NM_001009960, NM_001083956, NM_001085366, NM_001085367, NM_001085368, NM_001363332, NM_001363333, NM_001363334, NM_024061, NM_138494

CCDS: CCDS34695, CCDS47655, CCDS5669, CCDS5670

Canonical transcript exons

ENST00000252713 — 3 exons

Exon	Start	End
ENSE00001834689	99558642	99558787
ENSE00003643295	99572245	99576453
ENSE00003706428	99560533	99560695

Expression profiles

Bgee: expression breadth ubiquitous, 260 present calls, max score 97.28.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 38.0120 / max 426.5401, expressed in 1716 samples.

FANTOM5 promoters (7 alternative TSS)

Promoter ID	TPM avg	Samples expressed
79887	22.4952	1667
79890	5.6681	1548
79886	2.7573	1309
79888	2.6517	1273
79885	2.2670	1100
79889	1.7938	825
79884	0.3790	167

Top tissues by expression

260 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ileal mucosa	UBERON:0000331	97.28	gold quality
colonic epithelium	UBERON:0000397	97.08	gold quality
upper arm skin	UBERON:0004263	96.77	gold quality
upper leg skin	UBERON:0004262	96.55	gold quality
body of pancreas	UBERON:0001150	96.30	gold quality
mucosa of stomach	UBERON:0001199	96.25	gold quality
kidney epithelium	UBERON:0004819	96.09	gold quality
cardiac muscle of right atrium	UBERON:0003379	95.91	gold quality
thymus	UBERON:0002370	95.72	gold quality
cartilage tissue	UBERON:0002418	95.62	gold quality
small intestine Peyer’s patch	UBERON:0003454	95.43	gold quality
lower esophagus	UBERON:0013473	95.43	gold quality
lower esophagus muscularis layer	UBERON:0035833	95.43	gold quality
muscle layer of sigmoid colon	UBERON:0035805	95.31	gold quality
right lung	UBERON:0002167	95.22	gold quality
vermiform appendix	UBERON:0001154	95.16	gold quality
esophagus	UBERON:0001043	95.14	gold quality
tibialis anterior	UBERON:0001385	95.05	gold quality
granulocyte	CL:0000094	95.04	gold quality
body of stomach	UBERON:0001161	95.04	gold quality
transverse colon	UBERON:0001157	95.03	gold quality
urinary bladder	UBERON:0001255	95.03	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	95.03	gold quality
monocyte	CL:0000576	95.00	gold quality
small intestine	UBERON:0002108	94.99	gold quality
leukocyte	CL:0000738	94.97	gold quality
skin of hip	UBERON:0001554	94.94	gold quality
esophagus mucosa	UBERON:0002469	94.93	gold quality
seminal vesicle	UBERON:0000998	94.92	gold quality
minor salivary gland	UBERON:0001830	94.91	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	9.81
E-MTAB-7249	no	353.30

Regulation

Is transcription factor: no

Upstream regulators (CollecTRI, top): STAT1

miRNA regulators (miRDB)

134 targeting ZNF655, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNA	Max score	Avg score	miRNA target_count
HSA-MIR-6867-5P	100.00	82.21	3464
HSA-MIR-6833-3P	100.00	70.63	3197
HSA-MIR-4768-5P	100.00	69.49	2861
HSA-MIR-190A-3P	100.00	80.35	5520
HSA-MIR-6873-3P	100.00	71.42	2626
HSA-MIR-4262	100.00	73.26	3931
HSA-MIR-3064-3P	100.00	70.09	1254
HSA-MIR-3613-3P	100.00	76.36	7965
HSA-MIR-181A-5P	99.99	72.96	2995
HSA-MIR-181B-5P	99.99	72.97	2996
HSA-MIR-181C-5P	99.99	72.95	2996
HSA-MIR-181D-5P	99.99	73.04	2997
HSA-MIR-5696	99.98	72.36	4487
HSA-MIR-548N	99.98	71.94	4170
HSA-MIR-8075	99.97	67.20	962
HSA-MIR-3148	99.97	75.06	6478
HSA-MIR-23A-3P	99.95	74.24	3163
HSA-MIR-23B-3P	99.95	74.24	3163
HSA-MIR-23C	99.95	73.92	3192
HSA-MIR-548AB	99.95	71.31	3488
HSA-MIR-559	99.95	72.28	3609
HSA-MIR-141-3P	99.94	72.79	2421
HSA-MIR-200A-3P	99.94	72.68	2420
HSA-MIR-548A-5P	99.94	71.27	3482
HSA-MIR-548AD-5P	99.94	71.23	3502
HSA-MIR-548AE-5P	99.94	71.23	3502
HSA-MIR-548AK	99.94	71.24	3488
HSA-MIR-548AM-5P	99.94	71.24	3488
HSA-MIR-548AP-5P	99.94	71.14	3489
HSA-MIR-548AQ-5P	99.94	71.34	3426

Literature-anchored findings (GeneRIF, showing 2)

• ZNF655 is involved in development and progression of non-small-cell lung cancer. (PMID:34144060)
• ZNF655 promotes the progression of hepatocellular carcinoma through PSMB8. (PMID:37272200)

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Zfp655	ENSMUSG00000007812
rattus_norvegicus	Zfp655	ENSRNOG00000060129

Paralogs (176): ZNF195 (ENSG00000005801), ZNF112 (ENSG00000062370), ZNF275 (ENSG00000063587), ZNF37A (ENSG00000075407), ZNF510 (ENSG00000081386), ZNF506 (ENSG00000081665), ZNF268 (ENSG00000090612), MZF1 (ENSG00000099326), ZNF629 (ENSG00000102870), ZNF175 (ENSG00000105497), ZNF85 (ENSG00000105750), ZFP30 (ENSG00000120784), ZNF45 (ENSG00000124459), ZNF391 (ENSG00000124613), ZNF436 (ENSG00000125945), ZNF484 (ENSG00000127081), ZNF835 (ENSG00000127903), ZNF780B (ENSG00000128000), ZSCAN10 (ENSG00000130182), ZNF317 (ENSG00000130803), ZNF331 (ENSG00000130844), ZNF227 (ENSG00000131115), ZNF141 (ENSG00000131127), ZNF132 (ENSG00000131849), ZNF189 (ENSG00000136870), ZIM3 (ENSG00000141946), ZFP14 (ENSG00000142065), ZNF514 (ENSG00000144026), ZNF300 (ENSG00000145908), RBAK (ENSG00000146587), ZNF157 (ENSG00000147117), ZNF182 (ENSG00000147118), ZNF41 (ENSG00000147124), ZNF7 (ENSG00000147789), ZNF117 (ENSG00000152926), ZNF221 (ENSG00000159905), ZNF235 (ENSG00000159917), ZNF714 (ENSG00000160352), ZNF577 (ENSG00000161551), ZNF12 (ENSG00000164631)

Protein

Protein identifiers

Zinc finger protein 655 — Q8N720 (reviewed: Q8N720)

Alternative names: Vav-interacting Krueppel-like protein

All UniProt accessions (11): C9IYG2, C9J0V9, C9J9R2, C9JNK1, C9JS03, C9JUB9, Q8N720, F8WCS2, F8WDU5, F8WE52, F8WEB1

UniProt curated annotations — full annotation on UniProt →

Function. Probable transcription factor.

Subunit / interactions. Interacts with VAV1 and CDK4. Interacts with INTS13; promoting association with the integrator complex.

Subcellular location. Nucleus.

Similarity. Belongs to the krueppel C2H2-type zinc-finger protein family.

Isoforms (4)

UniProt ID	Names	Canonical?
Q8N720-1	1	yes
Q8N720-2	2
Q8N720-3	3
Q8N720-4	4

RefSeq proteins (11): NP_001009958, NP_001009960, NP_001077425, NP_001078835, NP_001078836, NP_001078837, NP_001350261, NP_001350262, NP_001350263, NP_076966, NP_612503* (*=MANE)

Domains & families (InterPro)

ID	Name	Type
IPR013087	Znf_C2H2_type	Domain
IPR036236	Znf_C2H2_sf	Homologous_superfamily
IPR050826	Krueppel_C2H2_ZnFinger	Family

Pfam: PF00096

UniProt features (29 total): mutagenesis site 7, zinc finger region 6, splice variant 5, cross-link 3, helix 2, chain 1, sequence variant 1, sequence conflict 1, modified residue 1, region of interest 1, compositionally biased region 1

Structure

Experimental structures (PDB)

1 structures.

PDB	Method	Resolution (Å)
8PK6	X-RAY DIFFRACTION	3.21

Predicted structure (AlphaFold)

Model	pLDDT	Fraction very-high
AF-Q8N720-F1	54.05	0.00

Functional residue map

Curated UniProt residues grouped by drug-discovery relevance — catalytic, ligand-binding, modification, and mutation-validated positions. Source: UniProtKB sequence features.

Post-translational modifications (4): 190, 201, 60, 77

Mutagenesis-validated functional residues (7):

Position	Phenotype
102–103	decreased interaction with ints13 component of the integrator complex.
102	abolished interaction with ints13 component of the integrator complex.
106–107	decreased interaction with ints13 component of the integrator complex.
106	abolished interaction with ints13 component of the integrator complex.
108	does not affect interaction with ints13 component of the integrator complex.
113	abolished interaction with ints13 component of the integrator complex.
152–153	does not affect interaction with ints13 component of the integrator complex.

Function

Pathways and Gene Ontology

Reactome pathways

1 pathways

ID	Pathway
R-HSA-212436	Generic Transcription Pathway

MSigDB gene sets: 182 (showing top): GSE37336_LY6C_POS_VS_NEG_NAIVE_CD4_TCELL_UP, GSE45365_NK_CELL_VS_BCELL_UP, RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP, ACTACCT_MIR196A_MIR196B, GGTGTGT_MIR329, GCM_ZNF198, GOBP_CELL_CYCLE_PHASE_TRANSITION, LINDGREN_BLADDER_CANCER_CLUSTER_3_DN, AGTCTTA_MIR499, VERNELL_RETINOBLASTOMA_PATHWAY_DN, GOBP_NEGATIVE_REGULATION_OF_CELL_CYCLE_PROCESS, MODULE_239, GOBP_NEGATIVE_REGULATION_OF_CELL_CYCLE, GOBP_REGULATION_OF_CELL_CYCLE, GOBP_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION

GO Biological Process (3): regulation of transcription by RNA polymerase II (GO:0006357), negative regulation of G1/S transition of mitotic cell cycle (GO:2000134), regulation of DNA-templated transcription (GO:0006355)

GO Molecular Function (6): RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978), DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981), zinc ion binding (GO:0008270), DNA binding (GO:0003677), protein binding (GO:0005515), metal ion binding (GO:0046872)

GO Cellular Component (3): nucleus (GO:0005634), nucleolus (GO:0005730), cytoplasm (GO:0005737)

Reactome top-level categories

Rollup of top-1 pathways:

Category	Pathways
RNA Polymerase II Transcription	1

GO top-level categories

Rollup of top GO terms by namespace:

Category	Terms
RNA polymerase II transcription regulatory region sequence-specific DNA binding	2
regulation of DNA-templated transcription	1
transcription by RNA polymerase II	1
G1/S transition of mitotic cell cycle	1
negative regulation of mitotic cell cycle phase transition	1
negative regulation of cell cycle G1/S phase transition	1
regulation of G1/S transition of mitotic cell cycle	1
DNA-templated transcription	1
regulation of gene expression	1
regulation of RNA biosynthetic process	1
cis-regulatory region sequence-specific DNA binding	1
chromatin	1
DNA-binding transcription factor activity	1
regulation of transcription by RNA polymerase II	1
transition metal ion binding	1
nucleic acid binding	1
binding	1
cation binding	1
intracellular membrane-bounded organelle	1
nuclear lumen	1
intracellular membraneless organelle	1
intracellular anatomical structure	1
cellular anatomical structure	1

Protein interactions and networks

STRING

526 interactions, top by confidence (×1000):

Protein A	Protein B	Partner UniProt	Score
ZNF655	ANKHD1	Q8IWZ3	475
ZNF655	VAV1	P15498	461
ZNF655	GAS2L2	Q8NHY3	358
ZNF655	FAM222B	Q8WU58	341
ZNF655	STAU1	O95793	325
ZNF655	TMEM87A	Q8NBN3	324
ZNF655	ABCA7	Q8IZY2	314
ZNF655	ZNF862	O60290	305
ZNF655	SORL1	Q92673	302
ZNF655	UNC5C	O95185	302
ZNF655	C2orf74	A8MZ97	300
ZNF655	SSC4D	Q8WTU2	293
ZNF655	TREM2	Q9NZC2	293
ZNF655	OR8G5	Q8NG78	293
ZNF655	TMEFF2	Q9UIK5	285

IntAct

506 interactions, top by confidence:

A	B	Type	Score
RINT1	ZNF655	psi-mi:“MI:0915”(physical association)	0.670
CBY2	ZNF655	psi-mi:“MI:0915”(physical association)	0.670
ZNF655	RINT1	psi-mi:“MI:0915”(physical association)	0.670
ZNF655	CBY2	psi-mi:“MI:0915”(physical association)	0.670
ZNF655	TRAF2	psi-mi:“MI:0915”(physical association)	0.560
MED21	ZNF655	psi-mi:“MI:0915”(physical association)	0.560
ZNF655	KRT40	psi-mi:“MI:0915”(physical association)	0.560
MAGEA2B	ZNF655	psi-mi:“MI:0915”(physical association)	0.560
KIFC3	ZNF655	psi-mi:“MI:0915”(physical association)	0.560
CARD9	ZNF655	psi-mi:“MI:0915”(physical association)	0.560
KRT40	ZNF655	psi-mi:“MI:0915”(physical association)	0.560
CAPN7	ZNF655	psi-mi:“MI:0915”(physical association)	0.560
USHBP1	ZNF655	psi-mi:“MI:0915”(physical association)	0.560
INTS10	ZNF655	psi-mi:“MI:0915”(physical association)	0.560

BioGRID (202): ZNF655 (Two-hybrid), ZNF655 (Two-hybrid), ZNF655 (Two-hybrid), ZNF655 (Two-hybrid), ZNF655 (Two-hybrid), KRT40 (Two-hybrid), SPERT (Two-hybrid), MAGEA2B (Two-hybrid), ZNF655 (Affinity Capture-MS), ZNF655 (Affinity Capture-MS), ZNF655 (Two-hybrid), ZNF655 (Two-hybrid), ZNF655 (Two-hybrid), ZNF655 (Two-hybrid), KRTAP4-12 (Two-hybrid)

ESM2 similar proteins: A1KXM5, A1YFC1, A1YGK6, A2T7F2, A7KBS4, B2RXC5, E1JH25, G3X9G7, O96001, P16531, P18748, P34307, P88825, Q2EI21, Q3URU2, Q3V0C1, Q4V8E9, Q5JRM2, Q5R7U0, Q5RDG2, Q5RE50, Q5REF1, Q5SRN2, Q5SS00, Q5U4C1, Q6H236, Q6P1M9, Q6ZN11, Q810T2, Q8BUY8, Q8N3K9, Q8N660, Q8N720, Q8N859, Q8R2V3, Q920R4, Q921B4, Q923B3, Q95JY5, Q96D09

Diamond homologs: Q8N720, Q9CZP3

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

86 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	74
Likely benign	6
Benign	1

Top pathogenic / likely-pathogenic (0)

SpliceAI

1553 predictions. Top by Δscore:

Variant	Effect	Δscore
7:99560531:A:AG	acceptor_gain	1.0000
7:99560531:AGT:A	acceptor_gain	1.0000
7:99560532:G:GG	acceptor_gain	1.0000
7:99560532:GTG:G	acceptor_gain	1.0000
7:99560532:GTGAT:G	acceptor_gain	1.0000
7:99560692:GGGG:G	donor_gain	1.0000
7:99560693:GGG:G	donor_gain	1.0000
7:99560693:GGGG:G	donor_gain	1.0000
7:99560694:GG:G	donor_gain	1.0000
7:99560694:GGG:G	donor_gain	1.0000
7:99560695:GG:G	donor_gain	1.0000
7:99562491:CTGGG:C	donor_loss	1.0000
7:99562492:TGGGT:T	donor_loss	1.0000
7:99562493:GGGT:G	donor_loss	1.0000
7:99562495:GT:G	donor_loss	1.0000
7:99562496:T:G	donor_loss	1.0000
7:99558789:T:G	donor_loss	0.9900
7:99558790:GAG:G	donor_loss	0.9900
7:99560528:TGCA:T	acceptor_loss	0.9900
7:99560529:GCA:G	acceptor_loss	0.9900
7:99560530:CA:C	acceptor_loss	0.9900
7:99560532:GT:G	acceptor_gain	0.9900
7:99560532:GTGA:G	acceptor_gain	0.9900
7:99560581:G:GT	donor_gain	0.9900
7:99560684:G:T	donor_gain	0.9900
7:99560694:GGGT:G	donor_loss	0.9900
7:99560695:GGT:G	donor_loss	0.9900
7:99560697:T:A	donor_loss	0.9900
7:99560697:T:TC	donor_loss	0.9900
7:99562493:GG:G	donor_gain	0.9900

AlphaMissense

3327 scored. Top likely-pathogenic:

Variant	Protein change	am_pathogenicity
7:99572853:T:C	F249L	0.995
7:99572855:C:A	F249L	0.995
7:99572855:C:G	F249L	0.995
7:99572769:T:C	F221L	0.993
7:99572771:C:A	F221L	0.993
7:99572771:C:G	F221L	0.993
7:99572798:T:A	H230Q	0.990
7:99572798:T:G	H230Q	0.990
7:99572810:T:A	H234Q	0.990
7:99572810:T:G	H234Q	0.990
7:99572878:G:C	R257P	0.990
7:99572788:T:C	L227P	0.989
7:99572796:C:G	H230D	0.989
7:99572800:A:C	Q231P	0.987
7:99572880:C:G	H258D	0.987
7:99572335:T:C	L76P	0.986
7:99573042:T:C	F312L	0.986
7:99573044:C:A	F312L	0.986
7:99573044:C:G	F312L	0.986
7:99572882:T:A	H258Q	0.985
7:99572882:T:G	H258Q	0.985
7:99572416:T:C	L103P	0.983
7:99572748:T:C	C214R	0.983
7:99572770:T:C	F221S	0.983
7:99572872:T:C	L255P	0.982
7:99572894:C:A	H262Q	0.982
7:99572894:C:G	H262Q	0.982
7:99573273:T:C	F389L	0.982
7:99573275:C:A	F389L	0.982
7:99573275:C:G	F389L	0.982

dbSNP variants (sampled 300 via entrez): RS1000018298 (7:99568666 C>T), RS1000051968 (7:99558820 C>T), RS1000485501 (7:99568284 G>A,T), RS1000654673 (7:99570294 T>G), RS1000722854 (7:99558609 C>T), RS1000776518 (7:99564760 G>A), RS1000829527 (7:99563433 C>T), RS1001075085 (7:99558778 C>G,T), RS1001482796 (7:99574465 A>G), RS1001498757 (7:99565676 C>T), RS1001742771 (7:99573335 A>C,G,T), RS1001783177 (7:99565985 T>C), RS1002127509 (7:99559635 T>A), RS1002159700 (7:99566680 C>G,T), RS1002187295 (7:99566382 A>G)

Disease associations

OMIM: gene MIM:617891 | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

3 associations (top):

Study	Trait	p-value
GCST006249_21	Serum metabolite levels	4.000000e-11
GCST006249_22	Serum metabolite levels	2.000000e-12
GCST006249_46	Serum metabolite levels	4.000000e-21

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

45 total (human), top 30 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Valproic Acid	affects expression, decreases expression, increases expression	3
trichostatin A	affects cotreatment, decreases expression	2
FR900359	increases phosphorylation	1
TAK-243	increases sumoylation	1
geldanamycin	increases expression	1
methylmercuric chloride	decreases expression	1
alpha-pinene	affects cotreatment, increases expression, increases abundance	1
sodium arsenite	increases expression	1
manganese chloride	increases abundance, increases expression	1
methacrylaldehyde	increases expression, increases abundance, affects cotreatment	1
di-n-butylphosphoric acid	affects expression	1
CGP 52608	increases reaction, affects binding	1
K 7174	increases expression	1
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	affects cotreatment, decreases expression	1
torcetrapib	increases expression	1
abrine	increases expression	1
dorsomorphin	affects cotreatment, decreases expression	1
Resveratrol	affects cotreatment, increases expression	1
Temozolomide	affects response to substance	1
Sunitinib	increases expression	1
Acetaminophen	decreases expression	1
Acrolein	affects cotreatment, increases expression, increases abundance	1
Air Pollutants	affects cotreatment, increases abundance, increases expression	1
Arsenic	affects methylation	1
Vehicle Emissions	increases abundance, increases expression	1
Benzene	increases expression	1
Caffeine	decreases phosphorylation	1
Carmustine	affects response to substance	1
Diethylstilbestrol	increases expression	1
Dimethyl Sulfoxide	increases expression	1

Cellosaurus cell lines

4 cell lines: 3 cancer cell line, 1 transformed cell line

First 10 cell lines (id-ordered, not curated):

Cellosaurus	Name	Category	Sex
CVCL_E2PV	HAP1 ZNF655 (-) 1	Cancer cell line	Male
CVCL_E2PW	HAP1 ZNF655 (-) 2	Cancer cell line	Male
CVCL_E2PX	HAP1 ZNF655 (-) 3	Cancer cell line	Male
CVCL_HD37	HEK293 eGFP-ZNF655	Transformed cell line	Female

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.