ZNF687-AS1

Summary

ZNF687-AS1 (ZNF687 antisense RNA 1, HGNC:54048) is a long non-coding RNA gene on chromosome 1q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54048
Approved symbol	ZNF687-AS1
Name	ZNF687 antisense RNA 1
Location	1q21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232671
Ensembl biotype	lncRNA
Entrez	100507670
RNAcentral	URS0000A76C56 — lncRNA, 641 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000447795, ENST00000494138, ENST00000660511, ENST00000661167, ENST00000814157, ENST00000814158, ENST00000814159, ENST00000814160, ENST00000814161

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000447795 — 2 exons

Exon	Start	End
ENSE00001686367	151281543	151281929
ENSE00003756841	151280024	151280258

Expression profiles

Bgee: expression breadth ubiquitous, 156 present calls, max score 85.79.

FANTOM5 (CAGE): breadth broad, TPM avg 0.9390 / max 50.1962, expressed in 387 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
14419	0.3373	173
14421	0.3308	110
14420	0.2709	112

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.79	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.53	gold quality
bone marrow cell	CL:0002092	75.10	gold quality
granulocyte	CL:0000094	71.30	gold quality
monocyte	CL:0000576	70.91	gold quality
parotid gland	UBERON:0001831	70.85	gold quality
leukocyte	CL:0000738	70.67	gold quality
cortical plate	UBERON:0005343	70.48	gold quality
ventricular zone	UBERON:0003053	68.21	gold quality
hindlimb stylopod muscle	UBERON:0004252	66.99	gold quality
right adrenal gland cortex	UBERON:0035827	66.83	gold quality
right adrenal gland	UBERON:0001233	66.44	gold quality
ganglionic eminence	UBERON:0004023	66.24	gold quality
stromal cell of endometrium	CL:0002255	65.11	gold quality
left adrenal gland	UBERON:0001234	64.78	gold quality
left adrenal gland cortex	UBERON:0035825	64.53	gold quality
prefrontal cortex	UBERON:0000451	63.61	gold quality
adrenal cortex	UBERON:0001235	63.28	gold quality
right lobe of liver	UBERON:0001114	63.03	gold quality
adrenal gland	UBERON:0002369	62.93	gold quality
islet of Langerhans	UBERON:0000006	62.70	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	62.32	gold quality
secondary oocyte	CL:0000655	62.24	gold quality
gall bladder	UBERON:0002110	62.15	gold quality
blood	UBERON:0000178	62.09	gold quality
muscle of leg	UBERON:0001383	61.86	gold quality
mucosa of transverse colon	UBERON:0004991	61.77	gold quality
adenohypophysis	UBERON:0002196	61.75	gold quality
gastrocnemius	UBERON:0001388	61.37	gold quality
pancreas	UBERON:0001264	61.12	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.73

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.