ZNF8-DT

Summary

ZNF8-DT (ZNF8 divergent transcript, HGNC:55280) is a long non-coding RNA gene on chromosome 19q13.43.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55280
Approved symbol	ZNF8-DT
Name	ZNF8 divergent transcript
Location	19q13.43
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000268516
Ensembl biotype	lncRNA
Entrez	105372482
RNAcentral	URS00026A1F98 — lncRNA, 2639 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000597230, ENST00000693494, ENST00000759878, ENST00000759879, ENST00000759880, ENST00000759881, ENST00000759882, ENST00000759883, ENST00000759884, ENST00000759885, ENST00000759887, ENST00000759888

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000597230 — 2 exons

Exon	Start	End
ENSE00004113028	58257270	58259691
ENSE00004113034	58278523	58278857

Expression profiles

Bgee: expression breadth ubiquitous, 161 present calls, max score 93.32.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 6.3804 / max 80.1642, expressed in 1703 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
182940	1.8922	1149
182942	1.7307	922
182941	1.7037	816
182939	1.0539	655

Top tissues by expression

248 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cardiac muscle of right atrium	UBERON:0003379	93.32	gold quality
left ventricle myocardium	UBERON:0006566	92.92	gold quality
kidney epithelium	UBERON:0004819	89.22	gold quality
buccal mucosa cell	CL:0002336	86.93	gold quality
upper arm skin	UBERON:0004263	84.46	gold quality
tendon of biceps brachii	UBERON:0008188	80.18	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.73	gold quality
epithelial cell of pancreas	CL:0000083	79.43	gold quality
sural nerve	UBERON:0015488	76.44	gold quality
medial globus pallidus	UBERON:0002477	75.94	silver quality
superficial temporal artery	UBERON:0001614	75.04	gold quality
globus pallidus	UBERON:0001875	74.81	silver quality
vastus lateralis	UBERON:0001379	74.60	gold quality
secondary oocyte	CL:0000655	74.29	silver quality
gingival epithelium	UBERON:0001949	74.29	gold quality
quadriceps femoris	UBERON:0001377	73.66	gold quality
apex of heart	UBERON:0002098	73.27	gold quality
vena cava	UBERON:0004087	72.98	gold quality
heart right ventricle	UBERON:0002080	72.85	gold quality
mucosa of paranasal sinus	UBERON:0005030	72.42	gold quality
cardiac ventricle	UBERON:0002082	72.00	gold quality
cardiac atrium	UBERON:0002081	71.96	gold quality
heart left ventricle	UBERON:0002084	71.94	gold quality
lower lobe of lung	UBERON:0008949	71.61	silver quality
colonic epithelium	UBERON:0000397	71.53	gold quality
heart	UBERON:0000948	71.42	gold quality
muscle tissue	UBERON:0002385	71.13	gold quality
gingiva	UBERON:0001828	70.93	gold quality
cardia of stomach	UBERON:0001162	70.83	gold quality
right atrium auricular region	UBERON:0006631	70.80	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.71

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.