ZNF84-DT

Summary

ZNF84-DT (ZNF84 divergent transcript, HGNC:53355) is a long non-coding RNA gene on chromosome 12q24.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53355
Approved symbol	ZNF84-DT
Name	ZNF84 divergent transcript
Location	12q24.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000246394
Ensembl biotype	lncRNA
Entrez	101928597
RNAcentral	URS0000125292 — lncRNA, 1151 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000443154, ENST00000592296, ENST00000701176, ENST00000812523

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000443154 — 3 exons

Exon	Start	End
ENSE00001964485	133034053	133034103
ENSE00004211632	133032659	133033304
ENSE00004211633	133036769	133037252

Expression profiles

Bgee: expression breadth ubiquitous, 104 present calls, max score 81.12.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0718 / max 17.5923, expressed in 24 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
134264	0.0718	24

Top tissues by expression

198 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.12	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.74	gold quality
buccal mucosa cell	CL:0002336	74.26	silver quality
left testis	UBERON:0004533	68.96	gold quality
right uterine tube	UBERON:0001302	68.63	gold quality
right testis	UBERON:0004534	68.20	gold quality
testis	UBERON:0000473	67.69	gold quality
ganglionic eminence	UBERON:0004023	61.47	gold quality
mucosa of paranasal sinus	UBERON:0005030	58.63	gold quality
secondary oocyte	CL:0000655	57.18	gold quality
monocyte	CL:0000576	56.69	gold quality
leukocyte	CL:0000738	56.61	silver quality
myocardium	UBERON:0002349	56.49	gold quality
fallopian tube	UBERON:0003889	56.47	gold quality
oocyte	CL:0000023	55.84	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.09	gold quality
nasal cavity epithelium	UBERON:0005384	53.06	gold quality
bronchial epithelial cell	CL:0002328	52.90	silver quality
bone marrow	UBERON:0002371	52.81	gold quality
vermiform appendix	UBERON:0001154	52.58	gold quality
prefrontal cortex	UBERON:0000451	52.07	gold quality
skin of hip	UBERON:0001554	51.66	silver quality
gastrocnemius	UBERON:0001388	50.59	gold quality
islet of Langerhans	UBERON:0000006	50.50	gold quality
trabecular bone tissue	UBERON:0002483	50.45	gold quality
pigmented layer of retina	UBERON:0001782	50.37	gold quality
blood	UBERON:0000178	49.98	gold quality
lower lobe of lung	UBERON:0008949	49.79	silver quality
mammalian vulva	UBERON:0000997	49.78	gold quality
medial globus pallidus	UBERON:0002477	48.56	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.