ZNRF3-AS1

Summary

ZNRF3-AS1 (ZNRF3 antisense RNA 1, HGNC:41927) is a long non-coding RNA gene on chromosome 22q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41927
Approved symbol	ZNRF3-AS1
Name	ZNRF3 antisense RNA 1
Location	22q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000177993
Ensembl biotype	lncRNA
Entrez	100874123
RNAcentral	URS0000233532 — lncRNA, 2170 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000325660, ENST00000796000, ENST00000796001, ENST00000796002

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000325660 — 3 exons

Exon	Start	End
ENSE00001267818	29024999	29027009
ENSE00001643791	29031084	29031156
ENSE00001718965	29031391	29031476

Expression profiles

Bgee: expression breadth ubiquitous, 103 present calls, max score 77.41.

Top tissues by expression

103 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.41	silver quality
uterine cervix	UBERON:0000002	64.71	silver quality
tonsil	UBERON:0002372	63.67	silver quality
hindlimb stylopod muscle	UBERON:0004252	57.99	silver quality
adrenal tissue	UBERON:0018303	56.91	gold quality
liver	UBERON:0002107	55.17	silver quality
sural nerve	UBERON:0015488	54.72	silver quality
small intestine	UBERON:0002108	53.79	silver quality
muscle tissue	UBERON:0002385	53.14	gold quality
prostate gland	UBERON:0002367	52.86	silver quality
nucleus accumbens	UBERON:0001882	51.85	gold quality
urinary bladder	UBERON:0001255	51.77	silver quality
monocyte	CL:0000576	50.70	silver quality
adrenal gland	UBERON:0002369	50.42	gold quality
bone marrow	UBERON:0002371	50.42	silver quality
blood	UBERON:0000178	49.88	silver quality
muscle of leg	UBERON:0001383	49.56	gold quality
gastrocnemius	UBERON:0001388	49.37	gold quality
lung	UBERON:0002048	49.30	gold quality
right adrenal gland	UBERON:0001233	49.27	gold quality
left adrenal gland cortex	UBERON:0035825	49.27	gold quality
left adrenal gland	UBERON:0001234	49.21	gold quality
kidney	UBERON:0002113	48.62	silver quality
myometrium	UBERON:0001296	48.39	gold quality
islet of Langerhans	UBERON:0000006	48.10	gold quality
calcaneal tendon	UBERON:0003701	48.10	silver quality
prefrontal cortex	UBERON:0000451	47.94	gold quality
corpus callosum	UBERON:0002336	47.82	silver quality
right lobe of liver	UBERON:0001114	47.51	silver quality
right adrenal gland cortex	UBERON:0035827	46.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.40

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.