ZNRF3-IT1

Summary

ZNRF3-IT1 (ZNRF3 intronic transcript 1, HGNC:41440) is a long non-coding RNA gene on chromosome 22q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41440
Approved symbol	ZNRF3-IT1
Name	ZNRF3 intronic transcript 1
Location	22q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235786
Ensembl biotype	lncRNA
Entrez	100874339
RNAcentral	URS00001D20A3 — lncRNA, 674 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000412798

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412798 — 2 exons

Exon	Start	End
ENSE00001595182	29018164	29018620
ENSE00001659048	28992721	28992937

Expression profiles

Bgee: expression breadth ubiquitous, 104 present calls, max score 92.73.

Top tissues by expression

104 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.73	gold quality
sural nerve	UBERON:0015488	86.72	gold quality
colonic epithelium	UBERON:0000397	76.34	gold quality
tonsil	UBERON:0002372	68.97	gold quality
skeletal muscle tissue	UBERON:0001134	67.42	gold quality
urinary bladder	UBERON:0001255	66.89	gold quality
uterine cervix	UBERON:0000002	66.52	gold quality
hindlimb stylopod muscle	UBERON:0004252	66.11	gold quality
liver	UBERON:0002107	61.76	gold quality
adrenal tissue	UBERON:0018303	61.50	gold quality
kidney	UBERON:0002113	56.59	gold quality
lung	UBERON:0002048	56.09	gold quality
placenta	UBERON:0001987	53.79	gold quality
superior frontal gyrus	UBERON:0002661	53.03	gold quality
monocyte	CL:0000576	52.57	gold quality
blood	UBERON:0000178	51.94	gold quality
primary visual cortex	UBERON:0002436	51.80	gold quality
islet of Langerhans	UBERON:0000006	51.67	gold quality
adult mammalian kidney	UBERON:0000082	51.59	gold quality
ovary	UBERON:0000992	51.53	gold quality
vermiform appendix	UBERON:0001154	51.34	gold quality
calcaneal tendon	UBERON:0003701	51.24	silver quality
endometrium	UBERON:0001295	51.23	silver quality
muscle of leg	UBERON:0001383	50.54	gold quality
prefrontal cortex	UBERON:0000451	49.37	gold quality
corpus callosum	UBERON:0002336	49.31	gold quality
adrenal gland	UBERON:0002369	49.31	gold quality
cortex of kidney	UBERON:0001225	48.94	gold quality
right lobe of liver	UBERON:0001114	48.84	silver quality
pancreas	UBERON:0001264	48.83	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.