ZSCAN31

Summary

ZSCAN31 (zinc finger and SCAN domain containing 31, HGNC:14097) is a protein-coding gene on chromosome 6p22.1, encoding Zinc finger and SCAN domain-containing protein 31 (Q96LW9). May function as a transcription factor.

This gene encodes a protein containing multiple C2H2-type zinc finger motifs. Alternative splicing results in multiple transcript variants.

Source: NCBI Gene 64288 — RefSeq curated summary.

At a glance

• GWAS associations: 30
• Clinical variants (ClinVar): 42 total
• MANE Select transcript: NM_030899

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:14097
Approved symbol	ZSCAN31
Name	zinc finger and SCAN domain containing 31
Location	6p22.1
Locus type	gene with protein product
Status	Approved
Ensembl gene	ENSG00000235109
Ensembl biotype	protein_coding
OMIM	610794
Entrez	64288

Gene structure

Transcript identifiers

Ensembl transcripts: 42 — 40 protein_coding, 2 protein_coding_CDS_not_defined

ENST00000344279, ENST00000396838, ENST00000414429, ENST00000414431, ENST00000426434, ENST00000426756, ENST00000434036, ENST00000435857, ENST00000439158, ENST00000439628, ENST00000439636, ENST00000444081, ENST00000446222, ENST00000446474, ENST00000447021, ENST00000453745, ENST00000476001, ENST00000481934, ENST00000611469, ENST00000881652, ENST00000881653, ENST00000881654, ENST00000881655, ENST00000881656, ENST00000881657, ENST00000881658, ENST00000881659, ENST00000917875, ENST00000917876, ENST00000962705, ENST00000962706, ENST00000962707, ENST00000962708, ENST00000962709, ENST00000962710, ENST00000962711, ENST00000962712, ENST00000962713, ENST00000962714, ENST00000962715, ENST00000962716, ENST00000962717

RefSeq mRNA: 8 — MANE Select: NM_030899 NM_001135215, NM_001135216, NM_001243241, NM_001243242, NM_001243243, NM_001243244, NM_030899, NM_145909

CCDS: CCDS4649, CCDS59001

Canonical transcript exons

ENST00000344279 — 4 exons

Exon	Start	End
ENSE00001715513	28329303	28329778
ENSE00001813641	28336082	28336148
ENSE00001975894	28324737	28326854
ENSE00003660835	28327383	28327533

Expression profiles

Bgee: expression breadth ubiquitous, 243 present calls, max score 89.03.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 3.3296 / max 96.0797, expressed in 1044 samples.

FANTOM5 promoters (8 alternative TSS)

Promoter ID	TPM avg	Samples expressed
72406	0.9797	607
72411	0.9300	366
72410	0.7969	308
72409	0.1893	98
72407	0.1825	69
72412	0.1194	51
72408	0.0992	42
72413	0.0326	12

Top tissues by expression

278 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	89.03	gold quality
right testis	UBERON:0004534	89.02	gold quality
testis	UBERON:0000473	86.90	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.79	gold quality
gall bladder	UBERON:0002110	86.44	gold quality
left ovary	UBERON:0002119	84.02	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.66	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	83.39	gold quality
right lobe of thyroid gland	UBERON:0001119	83.14	gold quality
muscle layer of sigmoid colon	UBERON:0035805	82.82	gold quality
ovary	UBERON:0000992	82.76	gold quality
islet of Langerhans	UBERON:0000006	82.72	gold quality
left lobe of thyroid gland	UBERON:0001120	82.43	gold quality
lower esophagus muscularis layer	UBERON:0035833	82.37	gold quality
lower esophagus	UBERON:0013473	82.36	gold quality
gingiva	UBERON:0001828	82.07	gold quality
hindlimb stylopod muscle	UBERON:0004252	82.06	gold quality
right ovary	UBERON:0002118	81.88	gold quality
thyroid gland	UBERON:0002046	81.60	gold quality
esophagus	UBERON:0001043	81.30	gold quality
body of uterus	UBERON:0009853	81.27	gold quality
body of stomach	UBERON:0001161	81.26	gold quality
gingival epithelium	UBERON:0001949	81.17	gold quality
cerebellar cortex	UBERON:0002129	81.06	gold quality
cerebellar hemisphere	UBERON:0002245	81.04	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	80.94	gold quality
body of pancreas	UBERON:0001150	80.77	gold quality
esophagus mucosa	UBERON:0002469	80.74	gold quality
right hemisphere of cerebellum	UBERON:0014890	80.58	gold quality
pancreas	UBERON:0001264	80.44	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.17

Regulation

Is transcription factor: yes

JASPAR motifs

Motif	Name	Family
MA1722.1	ZSCAN31	More than 3 adjacent zinc fingers
MA1722.2	ZSCAN31	More than 3 adjacent zinc fingers

JASPAR matrix evidence (PMIDs): PMID:27852650

miRNA regulators (miRDB)

72 targeting ZSCAN31, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNA	Max score	Avg score	miRNA target_count
HSA-MIR-3924	100.00	72.09	2394
HSA-MIR-4795-3P	100.00	74.62	4024
HSA-MIR-4531	99.99	69.70	3181
HSA-MIR-103A-3P	99.98	69.14	1595
HSA-MIR-107	99.98	69.14	1595
HSA-MIR-6825-5P	99.96	69.81	3431
HSA-MIR-590-3P	99.96	74.34	6478
HSA-MIR-9718	99.94	68.91	918
HSA-MIR-497-5P	99.92	71.83	2674
HSA-MIR-15A-5P	99.90	72.80	2787
HSA-MIR-15B-5P	99.90	72.78	2798
HSA-MIR-16-5P	99.90	72.80	2780
HSA-MIR-195-5P	99.90	72.81	2805
HSA-MIR-627-3P	99.90	71.42	3316
HSA-MIR-424-5P	99.89	71.90	2641
HSA-MIR-6838-5P	99.89	71.94	2690
HSA-MIR-5582-3P	99.86	72.48	4221
HSA-MIR-3180-5P	99.82	69.12	2422
HSA-MIR-4495	99.82	72.08	3080
HSA-MIR-448	99.79	72.37	2103
HSA-MIR-3150A-3P	99.76	64.44	1640
HSA-MIR-6763-5P	99.76	64.68	1767
HSA-MIR-4320	99.75	65.80	793
HSA-MIR-92A-2-5P	99.75	67.01	2164
HSA-MIR-3059-5P	99.70	69.93	2491
HSA-MIR-580-3P	99.67	69.23	1841
HSA-MIR-3175	99.65	66.30	2031
HSA-MIR-5700	99.64	69.88	2280
HSA-MIR-4328	99.57	71.06	4094
HSA-MIR-4524A-5P	99.57	71.73	1193

Literature-anchored findings (GeneRIF, showing 4)

• role in early human embryonic development (PMID:12147252)
• ZNF323 is a schizophrenia susceptibility gene whose expression may influence schizophrenia risk. (PMID:25759474)
• ZSCAN31 hypermethylation is associated with lung cancer. (PMID:28722770)
• Functional variants fine-mapping and gene function characterization provide insights into the role of ZNF323 in schizophrenia pathogenesis. (PMID:33522098)

Cross-species orthologs

0 orthologs

Paralogs (30): ZNF263 (ENSG00000006194), ZNF213 (ENSG00000085644), ZNF500 (ENSG00000103199), ZKSCAN1 (ENSG00000106261), ZNF205 (ENSG00000122386), ZSCAN9 (ENSG00000137185), PGBD1 (ENSG00000137338), ZNF215 (ENSG00000149054), ZSCAN12 (ENSG00000158691), ZNF394 (ENSG00000160908), ZNF75A (ENSG00000162086), ZSCAN21 (ENSG00000166529), ZNF232 (ENSG00000167840), ZNF24 (ENSG00000172466), ZNF449 (ENSG00000173275), ZSCAN4 (ENSG00000180532), ZSCAN22 (ENSG00000182318), ZNF75D (ENSG00000186376), ZNF396 (ENSG00000186496), ZNF397 (ENSG00000186812), ZSCAN30 (ENSG00000186814), ZKSCAN4 (ENSG00000187626), ZSCAN23 (ENSG00000187987), ZKSCAN3 (ENSG00000189298), ZSCAN16 (ENSG00000196812), ZSCAN25 (ENSG00000197037), ZSCAN26 (ENSG00000197062), ZNF165 (ENSG00000197279), ZKSCAN8 (ENSG00000198315), ZNF853 (ENSG00000236609)

Protein

Protein identifiers

Zinc finger and SCAN domain-containing protein 31 — Q96LW9 (reviewed: Q96LW9)

Alternative names: Zinc finger protein 323

All UniProt accessions (12): Q96LW9, C9IYT1, C9J1X2, C9J423, C9J6S7, C9JAI0, C9JBH3, C9JH14, C9JHB1, C9JIC2, C9JPM5, C9JUE1

UniProt curated annotations — full annotation on UniProt →

Function. May function as a transcription factor. May be involved in the development of multiple embryonic organs.

Subcellular location. Nucleus.

Tissue specificity. Expressed at high levels in the lung, liver, and kidney, while weakly expressed in intestine, brain, muscle, cholecyst, heart, and pancreas.

Similarity. Belongs to the krueppel C2H2-type zinc-finger protein family.

Isoforms (2)

UniProt ID	Names	Canonical?
Q96LW9-1	1	yes
Q96LW9-2	2

RefSeq proteins (8): NP_001128687, NP_001128688, NP_001230170, NP_001230171, NP_001230172, NP_001230173, NP_112161, NP_665916 (=MANE)

Domains & families (InterPro)

ID	Name	Type
IPR003309	SCAN_dom	Domain
IPR013087	Znf_C2H2_type	Domain
IPR036236	Znf_C2H2_sf	Homologous_superfamily
IPR038269	SCAN_sf	Homologous_superfamily

Pfam: PF00096, PF02023

UniProt features (23 total): cross-link 7, zinc finger region 6, sequence variant 5, sequence conflict 2, chain 1, domain 1, splice variant 1

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Model	pLDDT	Fraction very-high
AF-Q96LW9-F1	67.96	0.09

Functional residue map

Curated UniProt residues grouped by drug-discovery relevance — catalytic, ligand-binding, modification, and mutation-validated positions. Source: UniProtKB sequence features.

Post-translational modifications (7): 191, 205, 215, 250, 358, 14, 149

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 97 (showing top): KOBAYASHI_EGFR_SIGNALING_24HR_UP, SENESE_HDAC1_AND_HDAC2_TARGETS_DN, ELK1_01, KIM_WT1_TARGETS_12HR_UP, GOMF_SEQUENCE_SPECIFIC_DNA_BINDING, DODD_NASOPHARYNGEAL_CARCINOMA_DN, GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_UP, KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN, VERHAAK_GLIOBLASTOMA_NEURAL, CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN, ATF2_UP.V1_DN, NOTCH_DN.V1_UP, GOMF_TRANSCRIPTION_REGULATOR_ACTIVITY, CAVIN1_TARGET_GENES, CBX5_TARGET_GENES

GO Biological Process (1): regulation of transcription by RNA polymerase II (GO:0006357)

GO Molecular Function (7): RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978), DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981), zinc ion binding (GO:0008270), sequence-specific double-stranded DNA binding (GO:1990837), DNA binding (GO:0003677), protein binding (GO:0005515), metal ion binding (GO:0046872)

GO Cellular Component (1): nucleus (GO:0005634)

GO top-level categories

Rollup of top GO terms by namespace:

Category	Terms
RNA polymerase II transcription regulatory region sequence-specific DNA binding	2
regulation of DNA-templated transcription	1
transcription by RNA polymerase II	1
cis-regulatory region sequence-specific DNA binding	1
chromatin	1
DNA-binding transcription factor activity	1
regulation of transcription by RNA polymerase II	1
transition metal ion binding	1
double-stranded DNA binding	1
sequence-specific DNA binding	1
nucleic acid binding	1
binding	1
cation binding	1
intracellular membrane-bounded organelle	1

Protein interactions and networks

STRING

488 interactions, top by confidence (×1000):

Protein A	Protein B	Partner UniProt	Score
ZSCAN31	NKAPL	Q5M9Q1	512
ZSCAN31	CCDC38	Q502W7	444
ZSCAN31	ARMC2	Q8NEN0	375
ZSCAN31	C3orf62	Q6ZUJ4	374
ZSCAN31	AS3MT	Q9HBK9	368
ZSCAN31	KNCN	A6PVL3	357
ZSCAN31	GSTCD	Q8NEC7	350
ZSCAN31	TSPAN18	Q96SJ8	348
ZSCAN31	BEND4	Q6ZU67	336
ZSCAN31	OR1C1	Q15619	328
ZSCAN31	GLT8D1	Q68CQ7	325
ZSCAN31	ZNF804A	Q7Z570	324
ZSCAN31	SPATA9	Q9BWV2	323
ZSCAN31	MPV17L	Q2QL34	323
ZSCAN31	H3BMD7	H3BMD7	310

IntAct

7 interactions, top by confidence:

A	B	Type	Score
ZSCAN31	DHX57	psi-mi:“MI:0914”(association)	0.530
CCL1	ZSCAN31	psi-mi:“MI:0915”(physical association)	0.370
DDIT3	ZSCAN31	psi-mi:“MI:0915”(physical association)	0.370
ZSCAN31	PDCD11	psi-mi:“MI:0914”(association)	0.350
ZSCAN31	IPO8	psi-mi:“MI:0914”(association)	0.350
TGIF2	ZNF213	psi-mi:“MI:0914”(association)	0.350

BioGRID (27): MTMR4 (Affinity Capture-MS), PIP5K1A (Affinity Capture-MS), CDKN2AIP (Affinity Capture-MS), DHX57 (Affinity Capture-MS), THAP11 (Affinity Capture-MS), LENG8 (Affinity Capture-MS), RPL26L1 (Affinity Capture-MS), TRMT1L (Affinity Capture-MS), YTHDC2 (Affinity Capture-MS), PDCD11 (Affinity Capture-MS), BBX (Affinity Capture-MS), DHX57 (Affinity Capture-MS), PIP5K1A (Affinity Capture-MS), MTMR4 (Affinity Capture-MS), LENG8 (Affinity Capture-MS)

ESM2 similar proteins: A1YEP8, A1YEV9, A1YFW2, A1YG26, A1YG48, A1YG60, A2T6E3, A2T6V8, A2T712, A2T736, A2T7D2, A2T7F4, A2T7L7, A2T812, A6QNZ0, O14709, O15535, O43296, O43309, P10073, P17023, P17097, P49910, Q07231, Q12901, Q15776, Q16670, Q1LZ87, Q3MJ62, Q53GI3, Q571J5, Q5JNZ3, Q5RAE6, Q5RBX0, Q5RCD9, Q5RJ54, Q7Z7L9, Q86W11, Q8IZ26, Q8NF99

Diamond homologs: A1YEP8, A1YEQ3, A1YEV9, A1YFW2, A1YFW6, A1YG26, A1YG48, A1YG60, A1YGJ4, A1YGK6, A2T6E3, A2T6V8, A2T6W2, A2T712, A2T736, A2T7D2, A2T7D7, A2T7F2, A2T7F4, A2T7L7, A2T812, A6QNZ0, A6QPT6, B2KFW1, O14709, O14771, O14978, O15535, O43309, O60304, O95125, P10073, P17022, P17028, P17029, P17040, P28698, P49910, P51815, P59923

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

42 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	33
Likely benign	2
Benign	1

Top pathogenic / likely-pathogenic (0)

SpliceAI

1387 predictions. Top by Δscore:

Variant	Effect	Δscore
6:28326851:CCAT:C	acceptor_gain	1.0000
6:28326852:CAT:C	acceptor_gain	1.0000
6:28326852:CATC:C	acceptor_gain	1.0000
6:28326854:TCTGG:T	acceptor_loss	1.0000
6:28326855:C:CC	acceptor_gain	1.0000
6:28327379:TTA:T	donor_loss	1.0000
6:28327380:TA:T	donor_loss	1.0000
6:28327381:A:AC	donor_gain	1.0000
6:28327381:ACC:A	donor_loss	1.0000
6:28327382:C:CC	donor_gain	1.0000
6:28327420:T:C	donor_gain	1.0000
6:28327530:GAGCC:G	acceptor_gain	1.0000
6:28327531:AGC:A	acceptor_gain	1.0000
6:28327531:AGCC:A	acceptor_gain	1.0000
6:28327532:GC:G	acceptor_gain	1.0000
6:28327532:GCC:G	acceptor_gain	1.0000
6:28327533:CC:C	acceptor_gain	1.0000
6:28327533:CCT:C	acceptor_gain	1.0000
6:28327534:C:CC	acceptor_gain	1.0000
6:28327542:A:T	acceptor_gain	1.0000
6:28350864:GCTT:G	donor_gain	1.0000
6:28327381:AC:A	donor_gain	0.9900
6:28327382:CC:C	donor_gain	0.9900
6:28327382:CCTTG:C	donor_gain	0.9900
6:28327529:GGAGC:G	acceptor_gain	0.9900
6:28327530:GAGC:G	acceptor_gain	0.9900
6:28327534:C:CA	acceptor_gain	0.9900
6:28327534:C:T	acceptor_gain	0.9900
6:28327535:T:C	acceptor_gain	0.9900
6:28327541:CAGG:C	acceptor_gain	0.9900

AlphaMissense

2697 scored. Top likely-pathogenic:

Variant	Protein change	am_pathogenicity
6:28326475:G:C	F304L	0.998
6:28326475:G:T	F304L	0.998
6:28326477:A:G	F304L	0.998
6:28326559:G:C	F276L	0.998
6:28326559:G:T	F276L	0.998
6:28326561:A:G	F276L	0.998
6:28326307:G:C	F360L	0.995
6:28326307:G:T	F360L	0.995
6:28326309:A:G	F360L	0.995
6:28326391:G:C	F332L	0.995
6:28326391:G:T	F332L	0.995
6:28326393:A:G	F332L	0.995
6:28326643:G:C	F248L	0.995
6:28326643:G:T	F248L	0.995
6:28326645:A:G	F248L	0.995
6:28326280:A:C	H369Q	0.993
6:28326280:A:T	H369Q	0.993
6:28326364:A:C	H341Q	0.992
6:28326364:A:T	H341Q	0.992
6:28326436:G:C	H317Q	0.991
6:28326436:G:T	H317Q	0.991
6:28326450:G:C	H313D	0.991
6:28326520:G:C	H289Q	0.991
6:28326520:G:T	H289Q	0.991
6:28326527:C:G	R287P	0.991
6:28326604:G:C	H261Q	0.991
6:28326604:G:T	H261Q	0.991
6:28326223:A:C	F388L	0.990
6:28326223:A:T	F388L	0.990
6:28326225:A:G	F388L	0.990

dbSNP variants (sampled 300 via entrez): RS1000006131 (6:28344466 C>G), RS1000103709 (6:28354337 G>A), RS1000153942 (6:28330643 A>T), RS1000194106 (6:28330940 A>C), RS1000224610 (6:28331033 A>G), RS1000327745 (6:28346646 G>A), RS1000374837 (6:28338925 C>T), RS1000579281 (6:28333416 C>T), RS1000612277 (6:28346156 T>G), RS1000649330 (6:28331481 T>C), RS1000934909 (6:28332924 A>C), RS1001349275 (6:28327248 T>C), RS1001504420 (6:28356306 T>C), RS1001555425 (6:28348272 A>G), RS1001681080 (6:28354299 T>C)

Disease associations

OMIM: gene MIM:610794 | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

30 associations (top):

Study	Trait	p-value
GCST001251_11	Pulmonary function	2.000000e-10
GCST003997_12	Myopia	1.000000e-12
GCST004521_112	Autism spectrum disorder or schizophrenia	3.000000e-26
GCST004521_115	Autism spectrum disorder or schizophrenia	3.000000e-16
GCST004521_166	Autism spectrum disorder or schizophrenia	4.000000e-24
GCST004521_212	Autism spectrum disorder or schizophrenia	5.000000e-14
GCST004521_23	Autism spectrum disorder or schizophrenia	2.000000e-11
GCST004521_43	Autism spectrum disorder or schizophrenia	2.000000e-27
GCST004521_6	Autism spectrum disorder or schizophrenia	2.000000e-15
GCST004521_7	Autism spectrum disorder or schizophrenia	2.000000e-15
GCST004521_73	Autism spectrum disorder or schizophrenia	8.000000e-11
GCST004521_77	Autism spectrum disorder or schizophrenia	1.000000e-19
GCST004748_92	Lung cancer	2.000000e-12
GCST004749_74	Lung cancer in ever smokers	7.000000e-10
GCST004946_75	Schizophrenia	5.000000e-36
GCST007559_16	Sleep duration (short sleep)	4.000000e-09
GCST008921_4	Asthma and major depressive disorder	2.000000e-11
GCST008921_6	Asthma and major depressive disorder	1.000000e-09
GCST008972_17	Urate levels	7.000000e-15
GCST009600_116	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy)	1.000000e-27
GCST010002_50	Refractive error	4.000000e-34
GCST010142_16	Fish- and plant-related diet	2.000000e-10
GCST010142_19	Fish- and plant-related diet	4.000000e-10
GCST010142_34	Fish- and plant-related diet	7.000000e-09
GCST010142_35	Fish- and plant-related diet	8.000000e-09
GCST010142_42	Fish- and plant-related diet	1.000000e-08
GCST010142_7	Fish- and plant-related diet	3.000000e-12
GCST010204_199	Low density lipoprotein cholesterol levels	4.000000e-16
GCST010702_75	Subcortical volume (MOSTest)	3.000000e-11
GCST010703_272	Brain morphology (MOSTest)	7.000000e-16

EFO canonical traits (6, from GWAS)

EFO ID	Trait name
EFO:0003892	pulmonary function measurement
EFO:0004314	forced expiratory volume
EFO:0004531	urate measurement
EFO:0008111	diet measurement
EFO:0004611	low density lipoprotein cholesterol measurement
EFO:0004346	neuroimaging measurement

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

54 total (human), top 30 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Valproic Acid	affects expression, affects cotreatment, decreases expression	8
sodium arsenite	affects expression, affects splicing, increases expression	3
trichostatin A	decreases expression, affects expression	2
Phenylmercuric Acetate	affects cotreatment, decreases expression	2
Cadmium Chloride	increases expression	2
p-Chloromercuribenzoic Acid	decreases expression, affects cotreatment	2
aristolochic acid I	increases expression	1
GSK-J4	decreases expression	1
TAK-243	increases sumoylation	1
sotorasib	affects cotreatment, increases expression	1
methylmercuric chloride	decreases expression	1
bisphenol A	affects cotreatment, decreases methylation	1
geraniol	increases expression	1
tris(1,3-dichloro-2-propyl)phosphate	increases expression	1
cobaltous chloride	increases expression	1
butyraldehyde	decreases expression	1
ferrous chloride	decreases expression	1
coumarin	increases phosphorylation	1
S-(1,2-dichlorovinyl)cysteine	increases expression, affects response to substance	1
pentanal	decreases expression	1
CGP 52608	affects binding, increases reaction	1
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	affects cotreatment, decreases expression	1
abrine	increases expression	1
dorsomorphin	affects cotreatment, decreases expression	1
jinfukang	affects cotreatment, decreases expression	1
trametinib	affects cotreatment, increases expression	1
(+)-JQ1 compound	decreases expression	1
NVP-BKM120	increases expression, affects cotreatment	1
Irinotecan	decreases expression	1
Arsenic Trioxide	increases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.